Systematic Analysis Underlying the Quality of the Scientific Evidence and Conflicts of Interest in Gastroenterology Practice Guidelines

2013 ◽  
Vol 108 (11) ◽  
pp. 1686-1693 ◽  
Author(s):  
Joseph D Feuerstein ◽  
Anne E Gifford ◽  
Mona Akbari ◽  
Jonathan Goldman ◽  
Daniel A Leffler ◽  
...  
2013 ◽  
Vol 144 (5) ◽  
pp. S-578
Author(s):  
Joseph D. Feuerstein ◽  
Mona Akbari ◽  
Daniel A. Leffler ◽  
Sunil Sheth ◽  
Adam S. S. Cheifetz

2014 ◽  
Vol 89 (1) ◽  
pp. 16-24 ◽  
Author(s):  
Joseph D. Feuerstein ◽  
Mona Akbari ◽  
Anne E. Gifford ◽  
Christine M. Hurley ◽  
Daniel A. Leffler ◽  
...  

2016 ◽  
Vol 5 (1) ◽  
pp. 9-10 ◽  
Author(s):  
Kerstin Stenius

Stenius, K. (2016). Addiction journals and the management of conflicts of interest. The International Journal Of Alcohol And Drug Research, 5(1), 9-10. doi:http://dx.doi.org/10.7895/ijadr.v5i1.233Scientific journals are crucial for a critical and open exchange of new research findings and as guardians of the quality of science. Today, as policy makers increasingly justify decision-making with references to scientific evidence, and research articles form the basis for evidence for specific measures, journals also have an indirect responsibility for how political decisions will be shaped.


PEDIATRICS ◽  
1995 ◽  
Vol 96 (4) ◽  
pp. 831-835 ◽  
Author(s):  
David A. Bergman

The past two decades have brought about major health care changes that have been driven by an ever-increasing cost of health care, practice variability, and medical malpractice litigation. These changes pose a challenge to pediatricians to contain costs, to reduce inappropriate use of health care services, and to demonstrate improved health care outcomes. To meet this challenge, a new "clinical tool kit" is required, one that will allow the pediatrician to analyze current practices and to document effective interventions. Two of the major tools in this kit are practice guidelines and outcomes assessment instruments. Practice guidelines are optimal care specifications that provide an analytic framework for defining high-quality care and measuring health care outcomes. Ideally, these guidelines should be developed from scientific evidence. In practice, however, scientific evidence to support the majority of recommendations made in guidelines is insufficient. Consequently, these recommendations are instead developed by expert consensus. Measurement of health outcomes includes clinical outcomes, patient satisfaction, cost and use, and quality of life. Health care organizations have become very sophisticated in measuring cost and use, but considerably less work has been done in the patient-centered areas of satisfaction and quality of life. This is particularly true for children, because measures are dependent on the viewpoint chosen (parent, child, or teacher), the age of the child, and the adjustment for severity of illness. Analyzing practice patterns and improving health outcomes will not be easy tasks to accomplish. For the pediatrician to use these tools in an efficient and effective manner, a new research agenda and new skills will be required.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Yosuke Hatakeyama ◽  
Kanako Seto ◽  
Rebeka Amin ◽  
Takefumi Kitazawa ◽  
Shigeru Fujita ◽  
...  

Abstract Background The Appraisal of Guidelines for Research & Evaluation (AGREE) II has been widely used to evaluate the quality of clinical practice guidelines (CPGs). While the relationship between the overall assessment of CPGs and scores of six domains were reported in previous studies, the relationship between items constituting these domains and the overall assessment has not been analyzed. This study aims to investigate the relationship between the score of each item and the overall assessment and identify items that could influence the overall assessment. Methods All Japanese CPGs developed using the evidence-based medicine method and published from 2011 to 2015 were used. They were independently evaluated by three appraisers using AGREE II. The evaluation results were analyzed using regression analysis to evaluate the influence of 6 domains and 23 items on the overall assessment. Results A total of 206 CPGs were obtained. All domains and all items except one were significantly correlated to the overall assessment. Regression analysis revealed that Domain 3 (Rigour of Development), Domain 4 (Clarity of Presentation), Domain 5 (Applicability), and Domain 6 (Editorial Independence) had influence on the overall assessment. Additionally, four items of AGREE II, clear selection of evidence (Item 8), specific/unambiguous recommendations (Item 15), advice/tools for implementing recommendations (Item 19), and conflicts of interest (Item 22), significantly influenced the overall assessment and explained 72.1% of the variance. Conclusions These four items may highlight the areas for improvement in developing CPGs.


2020 ◽  
Vol 11 ◽  
pp. 204062232092201
Author(s):  
Yang Zhao ◽  
Yanyan Li ◽  
Junwei Li ◽  
Weijuan Song ◽  
Jun Zhao ◽  
...  

Aim: The aim of this study was to evaluate the reporting quality of chronic kidney disease (CKD) guidelines. Methods: PubMed, EMBASE, and guideline-related websites were searched from 2008 to 2019. The CKD guidelines were included. Two reviewers used the RIGHT (Reporting Items for Practice Guidelines in Healthcare) checklist to assess the quality of guidelines and calculate the reporting proportion of each guideline. Results: We included 13 guidelines, of which 30.8% (4/13) were developed in Europe and about two-thirds (8/13) were published on their own website. The average quality of the 13 guidelines was 68.57%. The reporting proportion of the seven domains (i.e. basic information; background; evidence; recommendations; review and quality assurance; funding and declaration and management of interests; other information) were 65.39%, 81.73%, 63.08%, 69.23%, 53.85%, 63.46%, and 61.54%, respectively. Conclusion: CKD guidelines had moderate reporting quality in some domains, but guideline developers should increase the reporting items in basic information, guideline evidence, and recommendations. The RIGHT checklist would be a useful tool to improve the reporting quality of guidelines.


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