Characteristics and Survival of Interval and Sporadic Colorectal Cancer Patients: A Nationwide Population-Based Cohort Study

2013 ◽  
Vol 108 (8) ◽  
pp. 1332-1340 ◽  
Author(s):  
Rune Erichsen ◽  
John A Baron ◽  
Elena M Stoffel ◽  
Søren Laurberg ◽  
Robert S Sandler ◽  
...  
2009 ◽  
Vol 52 (1) ◽  
pp. 71-78 ◽  
Author(s):  
Lene H. Iversen ◽  
Mette Nørgaard ◽  
Jacob Jacobsen ◽  
Søren Laurberg ◽  
Henrik T. Sørensen

2020 ◽  
Vol 129 ◽  
pp. 4-14
Author(s):  
Miguel A. Luque-Fernandez ◽  
Karen Gonçalves ◽  
Elena Salamanca-Fernández ◽  
Daniel Redondo-Sanchez ◽  
Shing F. Lee ◽  
...  

2014 ◽  
Vol 45 (2) ◽  
pp. 160-168 ◽  
Author(s):  
W.-Y. Chiou ◽  
C.-M. Chang ◽  
K.-C. Tseng ◽  
S.-K. Hung ◽  
H.-Y. Lin ◽  
...  

Metabolites ◽  
2018 ◽  
Vol 8 (4) ◽  
pp. 91 ◽  
Author(s):  
Paul Wood ◽  
Michelle Donohue ◽  
John Cebak ◽  
Taylor Beckmann ◽  
Márcia Messias ◽  
...  

Background: There are currently no blood-based biomarkers for early diagnosis of colorectal cancer. Previous research has suggested that very-long-chain dicarboxylic acid (VLCDCA) 28:4 might be such a biomarker. Methods: Using high-resolution mass spectrometry, we analyzed VLCDCA 28:4 in the plasma of colorectal cancer patients in Italian [n = 62] and Brazilian [n = 52] cohorts. Additionally, we investigated individuals diagnosed with familial adenomatous polyposis (FAP; n = 27), one of the most important clinical forms of inherited susceptibility to colorectal cancer. Results: Decrements in plasma levels of VLCDCA 28:4 were monitored in colorectal cancer patients. These decreases were independent of the stage of tumor development and the individual’s age. However, no decrements in VLCDCA 28:4 were monitored in FAP patients. Conclusions: The plasma levels of VLCDCA 28:4 represent a potential biomarker of sporadic colorectal cancer. In addition, it is possible that resupply of this anti-inflammatory lipid may represent a new therapeutic strategy for CRC and inflammatory disorders.


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