scholarly journals Prevalence and characteristics of hypoxic hepatitis in the largest single-centre cohort of avian influenza A(H7N9) virus-infected patients with severe liver impairment in the intensive care unit

2016 ◽  
Vol 5 (1) ◽  
pp. 1-7 ◽  
Author(s):  
YiMin Zhang ◽  
JiMin Liu ◽  
Liang Yu ◽  
Ning Zhou ◽  
Wei Ding ◽  
...  
2021 ◽  
pp. 175114372110121
Author(s):  
Emanuele Russo ◽  
Giuliano Bolondi ◽  
Emiliano Gamberini ◽  
Domenico Pietro Santonastaso ◽  
Alessandro Circelli ◽  
...  

2017 ◽  
Vol 22 (19) ◽  
Author(s):  
Wenfei Zhu ◽  
Jianfang Zhou ◽  
Zi Li ◽  
Lei Yang ◽  
Xiyan Li ◽  
...  

With no or low virulence in poultry, avian influenza A(H7N9) virus has caused severe infections in humans. In the current fifth epidemic wave, a highly pathogenic avian influenza (HPAI) H7N9 virus emerged. The insertion of four amino acids (KRTA) at the haemagglutinin (HA) cleavage site enabled trypsin-independent infectivity of this virus. Although maintaining dual receptor-binding preference, its HA antigenicity was distinct from low-pathogenic avian influenza A(H7N9). The neuraminidase substitution R292K conferred a multidrug resistance phenotype.


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