scholarly journals Blockade of glucocorticoid receptors with RU486 attenuates cardiac damage and adipose tissue inflammation in a rat model of metabolic syndrome

2015 ◽  
Vol 38 (11) ◽  
pp. 741-750 ◽  
Author(s):  
Yuuri Takeshita ◽  
Shogo Watanabe ◽  
Takuya Hattori ◽  
Kai Nagasawa ◽  
Natsumi Matsuura ◽  
...  
2018 ◽  
Vol 16 ◽  
pp. 180-190 ◽  
Author(s):  
Simone Renner ◽  
Andreas Blutke ◽  
Britta Dobenecker ◽  
Georg Dhom ◽  
Timo D. Müller ◽  
...  

2017 ◽  
Vol 240 ◽  
pp. 332-338 ◽  
Author(s):  
Yuichiro Yamada ◽  
Shino Takeuchi ◽  
Mamoru Yoneda ◽  
Shogo Ito ◽  
Yusuke Sano ◽  
...  

Author(s):  
Marilia C.L. Seelaender ◽  
Miguel Luiz Batista

AbstractAdipose tissue inflammation plays a role in the etiology of many chronic diseases, and has been the focus of much attention in the context of obesity and metabolic syndrome. Similarly, during cancer cachexia, a syndrome that markedly increases cancer-associated morbidity and mortality, local adipose inflammation is reported in animal models and in patients, potentially contributing to the chronic systemic inflammation that constitutes the hallmark of this condition. We discuss, on the basis of information generated by obesity-related studies, the possible relation between adipose tissue inflammation and compromised steroid hormone secretion and action in cachexia.


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