Dissociation of body mass index, excess weight loss and body fat percentage trajectories after 3 years of gastric bypass: relationship with metabolic outcomes

2017 ◽  
Vol 41 (9) ◽  
pp. 1379-1387 ◽  
Author(s):  
J Gómez-Ambrosi ◽  
P Andrada ◽  
V Valentí ◽  
F Rotellar ◽  
C Silva ◽  
...  
2020 ◽  
Vol 2020 ◽  
pp. 1-6 ◽  
Author(s):  
Mohsen Mahmoudieh ◽  
Behrouz Keleidari ◽  
Naser Afshin ◽  
Masoud Sayadi Shahraki ◽  
Shahab Shahabi Shahmiri ◽  
...  

Introduction. Obesity is among the newest health matters that human beings are struggling with. Length of bypassed intestine is important in achievement of most weight loss and least nutritional and absorptive disorders. This study has aimed to assess short-term metabolic and nutritional effects of laparoscopic mini-gastric bypass/one anastomosis gastric bypass (MGB/OAGB) with a loop bypass length of 180 centimeters (cm) and compare these factors among patients with a body mass index (BMI) of 40–45 and 45–50 kilograms per square meter (kg/m2). Methods. 25 patients were put in group 1 (BMI = 40–45 kg/m2) and 25 patients in group 2 (BMI = 45–50 kg/m2). Patients’ BMI, postoperative weight, excess weight loss, and laboratory tests including fasting blood sugar (FBS), lipid profile, serum iron (Fe), ferritin, total iron-binding capacity (TIBC), 25-OH vitamin D, vitamin B12, liver function tests, and albumin were recorded preoperatively and within 3- and 6-month follow-up. Results. Weight loss and BMI reduction was significantly more in patients with higher BMI level (P=0.007), and excess weight loss was higher in patients with lower preoperative BMI level (P=0.007). Six-month follow-up showed statistically significant reduction in total cholesterol, total triglyceride, Fe, and vitamin B12 among patients with higher BMI level (P value <0.05). Conclusion. Based on this study, 180-cm intestinal bypassed length works for patients with a BMI level of 40–45 and 45–50 kg/m2, according to their significant decrease in weight, BMI, and improving glycolipid profile.


2019 ◽  
Vol 30 (3) ◽  
pp. 1086-1092 ◽  
Author(s):  
Daniel Eriksson Hogling ◽  
Jesper Bäckdahl ◽  
Anders Thorell ◽  
Mikael Rydén ◽  
Daniel P. Andersson

Abstract Background/Objective Body mass index (BMI) is central when evaluating treatment effect after gastric bypass. The metabolic impact of BMI-independent differences in body fat percentage (BF%) after gastric bypass is not fully understood. We compared metabolic and adipose tissue characteristics in women with high versus low BF% independent of BMI after obesity remission following gastric bypass. Subjects/Methods A cohort of 215 women was included at baseline. A total of 166 women were re-examined 2 years after gastric bypass, whereof 130 had obesity remission (BMI < 30 kg/m2). Anthropometric parameters, blood pressure, and lipids were measured. Total and regional body fat mass was determined by dual-energy X-ray absorptiometry. Insulin sensitivity was assessed by homeostasis model assessment of insulin resistance (HOMA-IR) and hyperinsulinemic euglycemic clamp (M value). Adipocyte size and number were determined. Results Of the 130 women with obesity remission, 64 had BF% ≥ 35 and 65 < 35. Independent of BMI, high BF% were associated with higher HOMA-IR (P = 0.021), lower M value (P = 0.0046), higher triglycerides (P = 0.013), higher visceral/total and android/gynoid fat mass ratios (P = 0.0032 and 0.0003 respectively), and larger subcutaneous fat cell volume (P < 0.0001) 2 years after gastric bypass. No differences in anthropometric measures, glucose, blood pressure, or fat cell number were observed. Conclusions Independent of BMI, patients with higher BF% displayed lower insulin sensitivity, higher triglyceride levels, central fat distribution, and larger subcutaneous adipocytes 2 years after gastric bypass. Thus, determination of BF% provides additional information of metabolic characteristics at follow-up of non-obese patients after gastric bypass.


2015 ◽  
Vol 11 (6) ◽  
pp. S98-S99
Author(s):  
Tara Mokhtari ◽  
Sayantan Deb ◽  
Lindsey Voller ◽  
Sophia Koontz ◽  
Dan Azagury ◽  
...  

2011 ◽  
Vol 7 (3) ◽  
pp. 388-389
Author(s):  
Hugo Sánchez ◽  
Rocío Durán ◽  
Florencia Vargas ◽  
Vianey Anduaga ◽  
Maureen Mosti ◽  
...  

BMJ ◽  
2021 ◽  
pp. n365
Author(s):  
Buyun Liu ◽  
Yang Du ◽  
Yuxiao Wu ◽  
Linda G Snetselaar ◽  
Robert B Wallace ◽  
...  

AbstractObjectiveTo examine the trends in obesity and adiposity measures, including body mass index, waist circumference, body fat percentage, and lean mass, by race or ethnicity among adults in the United States from 2011 to 2018.DesignPopulation based study.SettingNational Health and Nutrition Examination Survey (NHANES), 2011-18.ParticipantsA nationally representative sample of US adults aged 20 years or older.Main outcome measuresWeight, height, and waist circumference among adults aged 20 years or older were measured by trained technicians using standardized protocols. Obesity was defined as body mass index of 30 or higher for non-Asians and 27.5 or higher for Asians. Abdominal obesity was defined as a waist circumference of 102 cm or larger for men and 88 cm or larger for women. Body fat percentage and lean mass were measured among adults aged 20-59 years by using dual energy x ray absorptiometry.ResultsThis study included 21 399 adults from NHANES 2011-18. Body mass index was measured for 21 093 adults, waist circumference for 20 080 adults, and body fat percentage for 10 864 adults. For the overall population, age adjusted prevalence of general obesity increased from 35.4% (95% confidence interval 32.5% to 38.3%) in 2011-12 to 43.4% (39.8% to 47.0%) in 2017-18 (P for trend<0.001), and age adjusted prevalence of abdominal obesity increased from 54.5% (51.2% to 57.8%) in 2011-12 to 59.1% (55.6% to 62.7%) in 2017-18 (P for trend=0.02). Age adjusted mean body mass index increased from 28.7 (28.2 to 29.1) in 2011-12 to 29.8 (29.2 to 30.4) in 2017-18 (P for trend=0.001), and age adjusted mean waist circumference increased from 98.4 cm (97.4 to 99.5 cm) in 2011-12 to 100.5 cm (98.9 to 102.1 cm) in 2017-18 (P for trend=0.01). Significant increases were observed in body mass index and waist circumference among the Hispanic, non-Hispanic white, and non-Hispanic Asian groups (all P for trend<0.05), but not for the non-Hispanic black group. For body fat percentage, a significant increase was observed among non-Hispanic Asians (30.6%, 29.8% to 31.4% in 2011-12; 32.7%, 32.0% to 33.4% in 2017-18; P for trend=0.001), but not among other racial or ethnic groups. The age adjusted mean lean mass decreased in the non-Hispanic black group and increased in the non-Hispanic Asian group, but no statistically significant changes were found in other racial or ethnic groups.ConclusionsAmong US adults, an increasing trend was found in obesity and adiposity measures from 2011 to 2018, although disparities exist among racial or ethnic groups.


Medicine ◽  
2017 ◽  
Vol 96 (39) ◽  
pp. e8126 ◽  
Author(s):  
Yiu-Hua Cheng ◽  
Yu-Chung Tsao ◽  
I-Shiang Tzeng ◽  
Hai-Hua Chuang ◽  
Wen-Cheng Li ◽  
...  

2021 ◽  
pp. 1-18
Author(s):  
Matheus Pacheco ◽  
José Roberto de Maio Godoi Filho ◽  
José Nunes da Silva Filho ◽  
Josivana Pontes dos Santos ◽  
Edson Souza Farias

2019 ◽  
Vol 69 (12) ◽  
pp. 490-498 ◽  
Author(s):  
Yvonne Mühlig ◽  
Miriam Remy ◽  
Rolf Holle ◽  
André Scherag ◽  
Martin Wabitsch ◽  
...  

Zusammenfassung Einleitung Soziale Benachteiligung stellt eine Behandlungsbarriere für Jugendliche mit (extremer) Adipositas dar. Mit der Implementierung einer Spezialambulanz in Kooperation mit fünf Job-Centern sollte geprüft werden, ob arbeitslose Jugendliche mit Adipositas Interesse an einer Behandlung ihrer Adipositas haben und welche Teilnahmeraten sie in einem mehrstufigen Behandlungsprogramm aufweisen. Material und Methoden Jugendliche (15,0–24,9 Jahre) mit einem Body-Mass-Index (BMI) ≥30 kg/m2 erhielten das Angebot zur Beratung bzgl. Behandlungsmöglichkeiten der Adipositas im Job-Center. Interessierte Jugendliche wurden nach einer psychologischen Diagnostik in ein multimodales Behandlungsprogramm (6 Sitzungen) aufgenommen. Bei Interesse und bewiesener Adhärenz (Teilnahme an ≥5 Sitzungen) folgte ein Informationskurs (4 Sitzungen) und eine Indikationsprüfung für eine adipositaschirurgische Maßnahme. Ergebnisse Von 2012–2017 wurden 83 Jugendliche (im Mittel 21,1 Jahre, BMI 48,1 kg/m2, BMI 35,0–39,9 kg/m2: N=7, ≥ 40 kg/m2: N=71) eingeschlossen. 34 bewiesen ihre Adhärenz (≥5/6 Sitzungen in der multimodalen Adipositasintervention), 20 interessierten sich für einen adipositaschirurgischen Eingriff. Bisher wurden 11 Jugendliche operiert mit einer mittleren BMI-Reduktion von 14,3 kg/m2 3–36 Monate nach der Operation („Excess Weight Loss“ 27,3%) im Vergleich zu 3,8 kg/m2 6–48 Monate nach Behandlungsbeginn bei den nicht-operierten Jugendlichen. 13 Teilnehmer wurden auf dem ersten Arbeitsmarkt integriert. Diskussion Einige arbeitslose Jugendliche nahmen das Behandlungsangebot gut an und zeigten eine positive gesundheitliche und berufliche Entwicklung im Verlauf ihrer Teilnahme. Schlussfolgerung Die Implementierung einer Spezialambulanz für arbeitslose Jugendliche mit Adipositas in deutschen Job-Centern erweist sich als eine erfolgreiche Strategie, um diese oft unbehandelte Hochrisikogruppe zu charakterisieren und den individuellen Behandlungsbedarf zu ermitteln. Dieser Befund muss an einer größeren Stichprobe im Langzeitverlauf bestätigt werden.


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