The relationship of brachial-ankle pulse wave velocity to future cardiovascular disease events in the general Japanese population: the Takashima Study

Background: Studying the adherence of the population to the Atlantic Diet (AD) could be simplified by an easy and quickly applied dietary index. The aim of this study is to analyse the relationship of an index measuring compliance with recommendations regarding the Atlantic diet and physical activity with cardiovascular disease risk factors, cardiovascular risk factors, obesity indexes and arterial stiffness markers. Methods: We included 791 individuals from the EVIDENT study (lifestyles and arterial ageing), (52.3 ± 12 years, 61.7% women) without cardiovascular disease. Compliance with recommendations on AD was collected through the responses to a food frequency questionnaire, while physical activity was measured by accelerometer. The number of recommendations being met was estimated using a global scale between 0 and 14 points (a higher score representing greater adherence). Blood pressure, plasma lipid and glucose values and obesity rates were measured. Cardiovascular risk was estimated with the Framingham equation. Results: In the overall sample, 184 individuals (23.3%) scored between 0–3 on the 14-point index we created, 308 (38.9%) between 4 and 5 points, and 299 (37.8%) 6 or more points. The results of multivariate analysis yield a common tendency in which the group with an adherence score of at least 6 points shows lower figures for total cholesterol (p = 0.007) and triglycerides (p = 0.002). Similarly, overall cardiovascular risk in this group is the lowest (p < 0.001), as is pulse wave velocity (p = 0.050) and the mean values of the obesity indexes studied (p < 0.05 in all cases). Conclusion: The rate of compliance with the Atlantic diet and physical activity shows that greater adherence to these recommendations is linked to lower cardiovascular risk, lower total cholesterol and triglycerides, lower rates of obesity and lower pulse wave velocity values.

Download Full-text

The Relationship Between Level of End-Products of Tissue Glycation and Pulse Wave Velocity in Non-diabetic Patients With Cardiovascular Disease

Kardiologiia ◽

10.18565/cardio.2015.6.63-67 ◽

2015 ◽

Vol 6_2015 ◽

pp. 63-67 ◽

Cited By ~ 1

Author(s):

F.T. Ageev Ageev ◽

M.V. Vitsenia Vitsenia ◽

M.D. Smirnova Smirnova ◽

G.V. Mihailov Mihailov ◽

Keyword(s):

Cardiovascular Disease ◽

Pulse Wave Velocity ◽

Wave Velocity ◽

Pulse Wave ◽

Diabetic Patients ◽

End Products ◽

The Relationship

Download Full-text

P6.01 THE METHOD OF DISTANCE MEASUREMENT AND TORSO LENGTH INFLUENCES THE RELATIONSHIP OF PULSE WAVE VELOCITY TO CARDIOVASCULAR MORTALITY

Artery Research ◽

10.1016/j.artres.2011.10.087 ◽

2011 ◽

Vol 5 (4) ◽

pp. 171

Author(s):

J. Nemcsik ◽

Z.K. Németh ◽

P. Studinger ◽

I. Kiss ◽

T.E.H. Othmane ◽

...

Keyword(s):

Pulse Wave Velocity ◽

Wave Velocity ◽

Cardiovascular Mortality ◽

Pulse Wave ◽

Distance Measurement ◽

Relationship Of ◽

The Relationship

Download Full-text

GW26-e4375 The relationship of fasting glucose, blood pressure and homocysteine levels with brachial-ankle pulse wave velocity (baPWV) in Chinese hypertensive adults - CSPPT

Journal of the American College of Cardiology ◽

10.1016/j.jacc.2015.06.741 ◽

2015 ◽

Vol 66 (16) ◽

pp. C194

Author(s):

Ningling Sun

Keyword(s):

Blood Pressure ◽

Pulse Wave Velocity ◽

Wave Velocity ◽

Pulse Wave ◽

Fasting Glucose ◽

Relationship Of ◽

The Relationship

Download Full-text

Plasma expression of microRNA-425-5p and microRNA-451a as biomarkers of cardiovascular disease in rheumatoid arthritis patients

Scientific Reports ◽

10.1038/s41598-021-95234-w ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Delia Taverner ◽

Dídac Llop ◽

Roser Rosales ◽

Raimon Ferré ◽

Luis Masana ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Cardiovascular Disease ◽

Pulse Wave Velocity ◽

Wave Velocity ◽

Pulse Wave ◽

Disease Risk ◽

Intima Media Thickness ◽

Carotid Intima Media Thickness ◽

Media Thickness ◽

Epigenetic Biomarkers

AbstractTo validate in a cohort of 214 rheumatoid arthritis patients a panel of 10 plasmatic microRNAs, which we previously identified and that can facilitate earlier diagnosis of cardiovascular disease in rheumatoid arthritis patients. We identified 10 plasma miRs that were downregulated in male rheumatoid arthritis patients and in patients with acute myocardial infarction compared to controls suggesting that these microRNAs could be epigenetic biomarkers for cardiovascular disease in rheumatoid arthritis patients. Six of those microRNAs were validated in independent plasma samples from 214 rheumatoid arthritis patients and levels of expression were associated with surrogate markers of cardiovascular disease (carotid intima-media thickness, plaque formation, pulse wave velocity and distensibility) and with prior cardiovascular disease. Multivariate analyses adjusted for traditional confounders and treatments showed that decreased expression of microRNA-425-5p in men and decreased expression of microRNA-451 in women were significantly associated with increased (β = 0.072; p = 0.017) and decreased carotid intima-media thickness (β = −0.05; p = 0.013), respectively. MicroRNA-425-5p and microRNA-451 also increased the accuracy to discriminate patients with pathological carotid intima-media thickness by 1.8% (p = 0.036) in men and 3.5% (p = 0.027) in women, respectively. In addition, microRNA-425-5p increased the accuracy to discriminate male patients with prior cardiovascular disease by 3% (p = 0.008). Additionally, decreased expression of microRNA-451 was significantly associated with decreased pulse wave velocity (β = −0.72; p = 0.035) in overall rheumatoid arthritis population. Distensibility showed no significant association with expression levels of the microRNAs studied. We provide evidence of a possible role of microRNA-425-5p and microRNA-451 as useful epigenetic biomarkers to assess cardiovascular disease risk in patients with rheumatoid arthritis.

Download Full-text