scholarly journals The impact of feeding interval on feeding outcomes in very low birth-weight infants

2011 ◽  
Vol 31 (7) ◽  
pp. 481-486 ◽  
Author(s):  
S B DeMauro ◽  
S Abbasi ◽  
S Lorch
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
Low Birth Weight Infants ◽  
The Impact

Neurodevelopmental Outcome in Very Low Birth Weight Infants Exposed to Donor Milk

2021 ◽  
Author(s):  
Kousiki Patra ◽  
Michelle M. Greene ◽  
Grace Tobin ◽  
Gina Casini ◽  
Anita L. Esquerra-Zwiers ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
Neurodevelopmental Outcome ◽  
Regression Analyses ◽  
Low Birth Weight Infants ◽  
Donor Milk ◽  
Preterm Formula ◽  
Before And After ◽  
The Impact

Objective This study was aimed to evaluate the impact of donor milk (DM) received in the first 28 days of life (DOL) on neurodevelopmental (ND) outcome at 20-month corrected age (CA) in very low birth weight (VLBW) infants. Study Design A total of 84 infants born in 2011 to 2012 who received only mother's own milk (MOM) and/or preterm formula (PF) was compared with 69 infants born in 2013 to 2014 who received MOM and/or DM. Daily enteral intake of MOM, DM, and PF was collected through 28 DOL. ND outcomes were assessed with the Bayley-III. Multiple regression analyses were adjusted for the effect of social and neonatal risk factors, alongside era of birth on ND outcome. Results Infants exposed to DM were born to older mothers (p < 0.01) and had higher incidence of severe brain injury (p = 0.013). Although DM group infants received first feed at earlier DOL (p < 0.001), there were no differences in MOM intake at DOL 14 or 28 between the two groups. In regression analyses, DM group did not predict 20-month ND outcome. Conclusion There were no differences in ND outcome between infants born before and after the introduction of DM. This may have been due to the similar percent of MOM at DOL 14 and 28 in the two eras. Key Points

scholarly journals Effect of Fluid Bolus on Clinical Outcomes in Very Low Birth Weight Infants

2020 ◽  
Vol 25 (5) ◽  
pp. 437-444
Author(s):  
Shubham Bakshi ◽  
Taylor Koerner ◽  
Alexander Knee ◽  
Rachana Singh ◽  
Ruben Vaidya
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Clinical Outcomes ◽  
Very Low Birth Weight ◽  
Ductus Arteriosus ◽  
Adverse Outcomes ◽  
Low Birth Weight Infants ◽  
Fluid Bolus ◽  
Vlbw Infants ◽  
The Impact

OBJECTIVE Administration of fluid bolus in very low birth weight (VLBW) infants is a common practice in the NICU, but one without clear evidence demonstrating benefits in clinical outcomes. On the contrary, recent observational studies have suggested a potential detrimental effect of empiric fluid bolus in preterm infants, especially in the absence of clear indications. The aim of this study was to assess the impact of fluid bolus on various clinical outcomes in VLBW infants. METHODS Retrospective cohort study of VLBW infants born at ≤34 weeks' gestation and/or ≤1500-g birth weight at a single level III NICU from January 1, 2008, to December 31, 2013, and who received at least one fluid bolus within the first 48 hours of life. Outcomes studied were in-hospital mortality, need for home oxygen, incidence of chronic lung disease (CLD), prevalence of patent ductus arteriosus (PDA), and intraventricular hemorrhage (IVH). RESULTS Of 516 infants, 112 (21.7%) received a fluid bolus within the first 48 hours of life for various indications. Propensity models suggested no statistical difference for CLD or mortality, but exposed infants had an increased incidence of home on oxygen (p = 0.018), PDA prevalence (p = 0.008), and IVH prevalence (p = 0.038). CONCLUSIONS Fluid bolus in the first 48 hours of life may be associated with increased incidence of need for home oxygen and higher prevalence of PDA and IVH in VLBW infants. Future studies are needed to address these important adverse outcomes.

scholarly journals Impact of Different Types of Nosocomial Infection on the Neurodevelopmental Outcome of Very Low Birth Weight Infants

Children ◽  
2021 ◽  
Vol 8 (3) ◽  
pp. 207
Author(s):  
Karin Pichler ◽  
Vito Giordano ◽  
Gereon Tropf ◽  
Renate Fuiko ◽  
Angelika Berger ◽  
...  
Keyword(s):  
Risk Factor ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
Neurodevelopmental Outcome ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Low Birth Weight Infants ◽  
Neurodevelopmental Outcomes ◽  
The Impact

Nosocomial infections (NIs) are important conditions associated with mortality and morbidity in very low birth weight infants (VLBWIs). The aim of this study was to investigate the impact of NIs and the different subtypes on neurodevelopmental outcomes in a cohort of VLBWIs. VLBWIs born with a gestational age between 23 0/7 and 31 6/7 weeks in a level III neonatal center were enrolled. Neonatal morbidities as well as the neurodevelopmental outcome at 2 years of corrected age were analyzed. Six-hundred infants completed the study successfully. Of these, 38% experienced an NI episode. NIs were associated with an increased risk of neonatal complications, such as brain injury, bronchopulmonary dysplasia (BPD) and death, and were a significant risk factor for adverse motor development at 2 years of corrected age in our cohort of VLBWIs. The negative impact of NIs on neurodevelopmental outcomes was particularly associated with necrotizing enterocolitis (NEC), suspected NIs and Gram-positive NIs. This study demonstrated that NIs are a significant risk factor for both morbidity and mortality as well as adverse neurodevelopmental outcomes in VLBWIs.

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