scholarly journals Protective role of tumor necrosis factor (TNF) receptors in chronic intestinal inflammation: TNFR1 ablation boosts systemic inflammatory response

2013 ◽  
Vol 93 (9) ◽  
pp. 1024-1035 ◽  
Author(s):  
Yi Wang ◽  
Gencheng Han ◽  
Yu Chen ◽  
Ke Wang ◽  
Guijun Liu ◽  
...  
Keyword(s):  
Tumor Necrosis Factor ◽  
Inflammatory Response ◽  
Tumor Necrosis ◽  
Intestinal Inflammation ◽  
Protective Role ◽  
Systemic Inflammatory Response ◽  
Tnf Receptors ◽  
Chronic Intestinal Inflammation ◽  
Necrosis Factor

Role of tumor necrosis factor receptor 2 (TNFR2) in colonic epithelial hyperplasia and chronic intestinal inflammation in mice

2002 ◽  
Vol 122 (1) ◽  
pp. 134-144 ◽  
Author(s):  
Emiko Mizoguchi ◽  
Atsushi Mizoguchi ◽  
Hidetoshi Takedatsu ◽  
Elke Cario ◽  
Ype P. De Jong ◽  
...  
Keyword(s):  
Tumor Necrosis Factor ◽  
Tumor Necrosis ◽  
Intestinal Inflammation ◽  
Tumor Necrosis Factor Receptor ◽  
Epithelial Hyperplasia ◽  
Chronic Intestinal Inflammation ◽  
Necrosis Factor

scholarly journals Inactive Rhomboid Protein 2 Mediates Intestinal Inflammation by Releasing Tumor Necrosis Factor–α

2019 ◽  
Vol 26 (2) ◽  
pp. 242-253
Author(s):  
Jee Hyun Kim ◽  
Sung Wook Hwang ◽  
Jaemoon Koh ◽  
Jaeyoung Chun ◽  
Changhyun Lee ◽  
...  
Keyword(s):  
Tumor Necrosis Factor ◽  
Immune Cells ◽  
Tumor Necrosis ◽  
Tumor Necrosis Factor Α ◽  
Intestinal Inflammation ◽  
Converting Enzyme ◽  
Tnf Α ◽  
Factor Α ◽  
Necrosis Factor

Inactive rhomboid 2 (iRhom2) is an essential molecule required for the maturation of tumor necrosis factor–α–converting enzyme in immune cells, which regulates TNF-α release. The aim of this study was to investigate the role of iRhom2 in intestinal inflammation.

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