scholarly journals Large-scale spatiotemporal spike patterning consistent with wave propagation in motor cortex

2015 ◽  
Vol 6 (1) ◽  
Author(s):  
Kazutaka Takahashi ◽  
Sanggyun Kim ◽  
Todd P. Coleman ◽  
Kevin A. Brown ◽  
Aaron J. Suminski ◽  
...  

Author(s):  
Carlos Ortiz-Aleman ◽  
Ronald Martin ◽  
Jaime Urrutia-Fucugauchi ◽  
Mauricio Orozco del Castillo ◽  
Mauricio Nava-Flores


Author(s):  
Mitchell Tong Harris ◽  
M. Harper Langston ◽  
Pierre-David Letourneau ◽  
George Papanicolaou ◽  
James Ezick ◽  
...  


2015 ◽  
Vol 51 (3) ◽  
pp. 1-4 ◽  
Author(s):  
Dimitra A. Ketzaki ◽  
Ioannis T. Rekanos ◽  
Theodoros I. Kosmanis ◽  
Traianos V. Yioultsis




2021 ◽  
pp. 1-8
Author(s):  
Yixin Zhu ◽  
Lihua Gu

<b><i>Background:</i></b> Past research has indicated that repetitive transcranial magnetic stimulation (rTMS) on the pharyngeal motor cortex may be beneficial to poststroke dysphagic patients. In addition, some studies have supported that transcranial direct current stimulation (tDCS) over the pharyngeal motor cortex can improve swallowing function in poststroke dysphagia. However, some studies showed that rTMS and tDCS show no effect on poststroke dysphagia. This study aims to make a meta-analysis to investigate the therapy effect of rTMS and tDCS on poststroke dysphagia in randomized controlled trials (RCTs). <b><i>Methods:</i></b> We searched for studies published before March 2021 in databases (PubMed, Web of Science, MEDLINE, EMBASE, and Google Scholar). Meta-analysis was made to compute the results of included studies using STATA 12.0 software. <b><i>Results:</i></b> The present study shows a significant increase in the swallowing function in poststroke dysphagia given rTMS compared to those given sham rTMS (standardized mean difference [SMD] = 1.08, 95% confidence interval [CI] = 0.37–1.80, <i>I</i><sup>2</sup> = 81.2%, <i>p</i> &#x3c; 0.001). In addition, the study shows a significant increase in the swallowing function in poststroke dysphagia given tDCS (combined or not combined with conventional swallowing therapy), compared to those given sham tDCS (combined or not combined with conventional swallowing therapy) (SMD = 1.43, 95% CI = 0.73–2.13, <i>I</i><sup>2</sup> = 77.6%, <i>p</i> &#x3c; 0.001). <b><i>Conclusions:</i></b> The study demonstrates that rTMS and tDCS over the pharyngeal motor cortex show therapy effects on poststroke dysphagia. Many more large-scale, blinded RCTs are essential to investigate the effect of rTMS and tDCS on poststroke dysphagia.



2013 ◽  
Vol 110 (5) ◽  
pp. 1180-1189 ◽  
Author(s):  
Gustaf M. Van Acker ◽  
Sommer L. Amundsen ◽  
William G. Messamore ◽  
Hongyu Y. Zhang ◽  
Carl W. Luchies ◽  
...  

High-frequency, long-duration intracortical microstimulation (HFLD-ICMS) applied to motor cortex is recognized as a useful and informative method for corticomotor mapping by evoking natural-appearing movements of the limb to consistent stable end-point positions. An important feature of these movements is that stimulation of a specific site in motor cortex evokes movement to the same spatial end point regardless of the starting position of the limb. The goal of this study was to delineate effective stimulus parameters for evoking forelimb movements to stable spatial end points from HFLD-ICMS applied to primary motor cortex (M1) in awake monkeys. We investigated stimulation of M1 as combinations of frequency (30–400 Hz), amplitude (30–200 μA), and duration (0.5–2 s) while concurrently recording electromyographic (EMG) activity from 24 forelimb muscles and movement kinematics with a motion capture system. Our results suggest a range of parameters (80–140 Hz, 80–140 μA, and 1,000-ms train duration) that are effective and safe for evoking forelimb translocation with subsequent stabilization at a spatial end point. The mean time for stimulation to elicit successful movement of the forelimb to a stable spatial end point was 475.8 ± 170.9 ms. Median successful frequency and amplitude were 110 Hz and 110 μA, respectively. Attenuated parameters resulted in inconsistent, truncated, or undetectable movements, while intensified parameters yielded no change to movement end points and increased potential for large-scale physiological spread and adverse focal motor effects. Establishing cortical stimulation parameters yielding consistent forelimb movements to stable spatial end points forms the basis for a systematic and comprehensive mapping of M1 in terms of evoked movements and associated muscle synergies. Additionally, the results increase our understanding of how the central nervous system may encode movement.



2021 ◽  
Author(s):  
Chun-Man Liao ◽  
Franziska Mehrkens ◽  
Celine Hadziioannou ◽  
Ernst Niederleithinger

&lt;p&gt;The aim of this work is to investigate the application of seismological noise-based monitoring for bridge structures. A large-scale two-span concrete bridge model with a build-in post-tensioning system, which is exposed to environmental conditions, is chosen as our experimental test structure. Ambient seismic noise measurements were carried out under different pre-stressed conditions. Using the seismic interferometry technique, which is applied to the measurement data in the frequency domain, we reconstruct waveforms that relate to wave propagation in the structure. The coda wave interferometry technique is then implemented by comparing two waveforms recorded in two pre-stress states. Any relative seismic velocity changes are identified by determining the correlation coefficients and reveal the influence of the pre-stressing force. The decrease of the wave propagation velocity indicates the loss of the pre-stress and weakening stiffness due to opening or event extension of cracks. We conclude that the seismological methods used to estimate velocity change can be a promising tool for structural health monitoring of civil structures.&lt;/p&gt;







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