scholarly journals Suggestions for health information technology trials for respiratory disorders in low- and middle-income country settings: what can we learn from trials in high-income country settings?

2015 ◽  
Vol 25 (1) ◽  
Author(s):  
Niels H Chavannes ◽  
Robert S Du Puy ◽  
Chunxue Bai
2021 ◽  
Vol 118 (36) ◽  
pp. e2106652118
Author(s):  
Afshin Nikzad ◽  
Mohammad Akbarpour ◽  
Michael A. Rees ◽  
Alvin E. Roth

Kidney failure is a worldwide scourge, made more lethal by the shortage of transplants. We propose a way to organize kidney exchange chains internationally between middle-income countries with financial barriers to transplantation and high-income countries with many hard to match patients and patient–donor pairs facing lengthy dialysis. The proposal involves chains of exchange that begin in the middle-income country and end in the high-income country. We also propose a way of financing such chains using savings to US health care payers.


Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Vaani Garg ◽  
Rajesh Vedanthan ◽  
Samantha Sartori ◽  
Mark Woodward ◽  
Sameer Bansilal ◽  
...  

Introduction: Sedentary behavior (SB) has been associated with an increased risk of cardiovascular disease (CVD) in high-income countries. However, the burden and impact of SB in low- and middle-income countries is not well known. This study examined self-reported sedentary behavior and the association with CVD risk in Grenada, a middle-income country. Methods: A modified WHO STEPS survey was administered to a random sample of the Grenadian adult population, and sedentary behavior was assessed. Participants were asked to quantify the amount of time per day spent sitting (at home or work), reclining (excluding during sleep), or traveling in a vehicle. SB was assessed in hourly intervals and also grouped into two categories: 3 hours or less (approximately two thirds of the sample) and greater than 3 hours (approximately one third). Frequency of SB was compared across gender (age-standardized), age, and education groups. The relationship between SB and log-transformed 10-year CVD risk (Framingham) was evaluated using multivariable linear regression. Statistical analyses were performed using STATA v. 10. Results: Of 2622 participants, 32.4% reported greater than 3 hours per day of SB. SB was more common among men, among the youngest (age 18-29) and oldest (age 70+) individuals, and among those with higher education ( Table ). In univariate analysis, SB was adversely associated with 10-year CVD risk (p<0.05). However, after controlling for gender, age and education, SB was not significantly associated with 10-year CVD risk. Conclusions: Sedentary behavior in Grenada is more common among men, extremes of age, and higher education levels. Increased SB is not independently associated with 10-year CVD risk when controlling for gender, age and education. This is in contrast to findings in high-income countries. These results call for further exploration of the patterns of sedentary behavior, an emerging health issue in low- and middle-income countries, and its effect on CVD risk. Table Frequency of reported sedentary behavior (figures are %; all p-values within groups<0.05) N Greater than 3 hours per day Gender Men 1129 35.2 * Women 1493 30.3 * Age (years ) ≤18-29 634 39.1 30-39 428 30.6 40-49 580 23.6 50-59 448 28.1 60-69 249 28.1 ≥70 283 48.4 Education No schooling to Primary 1532 29.0 Secondary School 639 34.7 Post Graduate 419 39.9 * Age-standardized rates


2021 ◽  
pp. 622-631
Author(s):  
Andrés Gómez-De León ◽  
Perla R. Colunga-Pedraza ◽  
Luz Tarín-Arzaga ◽  
Emmanuel Bugarín-Estrada ◽  
Lilian Sung ◽  
...  

PURPOSE: Establishing research capacity in low- and middle-income countries (LMICs) is key for improving the outcomes of patients with hematologic diseases globally. Few studies have analyzed the contributions of LMICs to global hematology. The American Society of Hematology Meeting (ASH) is the largest international academic event where peer-reviewed contributions in our field are presented. METHODS: In this cross-sectional analysis, all abstracts accepted to ASH 2018 selected for a poster or oral presentation were reviewed. Those that had a contributing author from an LMIC were identified. The proportion of LMIC abstracts across categories was analyzed. Country of origin, high-income country participation, the presence of a conflict of interest (COI), and sponsorship were determined. RESULTS: From 4,871 abstracts reviewed, 506 had a contributing author from an LMIC (10.4%), with 277 (54.7%) contributions in partnership with a high-income country. LMIC-independent contributions corresponded to 19 of 1,026 oral abstracts (1.9%) and 209 of 3,845 posters (5.4%). Most abstracts from LMICs were clinical (n = 311; 61.5%) and multicentric in nature (n = 353; 69.8%). COI statements with the pharmaceutical industry were common (n = 214; 42.3%). Collaboration between LMICs was infrequent (n = 33; 6.5%). Upper-middle–income countries had 466 participations (81.5%), in comparison with 96 (16.8%) in low-middle–income and 10 (1.7%) in low-income countries. CONCLUSION: LMICs were responsible for a small fraction of abstracts at ASH18; low-income countries were practically absent. Almost half of accepted works represented a form of international collaboration, with clinical, multicenter studies predominating and COI disclosures a frequent and unexpected feature, reflecting the instrumental nature of LMIC participation and a lack of independent, robust, locally developed hematology research.


2019 ◽  
Author(s):  
Quan-Hoang Vuong

Valian rightly made a case for better recognition of women in science during the Nobel week in October 2018 (Valian, 2018). However, it seems most published views about gender inequality in Nature focused on the West. This correspondence shifts the focus to women in the social sciences and humanities (SSH) in a low- and middle-income country (LMIC).


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