scholarly journals Roux-en-Y Gastric Bypass Improves Liver Histology in Patients with Non-Alcoholic Fatty Liver Disease

2005 ◽  
Vol 13 (7) ◽  
pp. 1180-1186 ◽  
Author(s):  
Jeanne M. Clark ◽  
Amir R. A. Alkhuraishi ◽  
Steven F. Solga ◽  
Patricia Alli ◽  
Anna Mae Diehl ◽  
...  
Keyword(s):  
Gastric Bypass ◽  
Liver Disease ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Liver Histology ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease

We-P12:293 Associations between carotid artery wall thickness and liver histology in patients with non-alcoholic fatty liver disease

2006 ◽  
Vol 7 (3) ◽  
pp. 411
Author(s):  
G. Targher ◽  
L. Bertolini ◽  
R. Padovani ◽  
S. Rodella ◽  
L. Zenari ◽  
...  
Keyword(s):  
Liver Disease ◽  
Carotid Artery ◽  
Fatty Liver ◽  
Wall Thickness ◽  
Fatty Liver Disease ◽  
Liver Histology ◽  
Artery Wall ◽  
Alcoholic Fatty Liver ◽  
Carotid Artery Wall ◽  
Alcoholic Fatty Liver Disease

scholarly journals Effects of Roux-en-Y Gastric Bypass and Sleeve Gastrectomy on Non-Alcoholic Fatty Liver Disease: A 12-Month Follow-Up Study with Paired Liver Biopsies

2021 ◽  
Vol 10 (17) ◽  
pp. 3783
Author(s):  
Julie Steen Pedersen ◽  
Marte Opseth Rygg ◽  
Reza Rafiolsadat Serizawa ◽  
Viggo Bjerregaard Kristiansen ◽  
Nicolai J. Wewer Albrechtsen ◽  
...  
Keyword(s):  
Gastric Bypass ◽  
Sleeve Gastrectomy ◽  
Liver Disease ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Liver Steatosis ◽  
Plasma Lipid ◽  
Alcoholic Fatty Liver ◽  
Beneficial Effects ◽  
Alcoholic Fatty Liver Disease

Roux-en-Y gastric bypass (RYGB) improves, and can sometimes resolve, non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) but data based on histological assessment for the efficacy of sleeve gastrectomy (SG) in resolving NAFLD are sparse. Consequently, we aimed to compare the efficacy of RYGB vs. SG on NAFLD 12 months after surgery. In a prospective cohort study, 40 patients with obesity underwent bariatric surgery (16 RYGB and 24 SG). During surgery, a liver biopsy was taken and repeated 12 months later. NAFLD severity was evaluated using the NAFLD Activity Score (NAS) and Kleiner Fibrosis score. RYGB and SG patients were comparable at baseline. Mean (standard deviation, SD) NAS was 3.3 (0.9) in RYGB and 3.1 (1.4) in SG (p = 0.560) with similar degrees of steatosis, inflammation, and ballooning. Two RYGB patients, and six SG patients, had NASH (p = 0.439). Twelve months after surgery, NAS was significantly and comparably (p = 0.241) reduced in both RYGB (−3.00 (95% CI −3.79–−2.21), p < 0.001) and SG (−2.25 (95% CI −2.92–−1.59), p < 0.001) patients. RYGB patients had significantly more reduced (p = 0.007) liver steatosis (−0.91 (95% CI −1.47–−1.2) than SG patients (−0.33 (95% CI −0.54–−0.13) and greater improvement in the plasma lipid profile. Fibrosis declined non-significantly. NASH was resolved in seven of eight patients without a worsening of their fibrosis. RYGB and SG have similar beneficial effects on NAS and NASH without the worsening of fibrosis. RYGB is associated with a more pronounced reduction in liver steatosis.

P1067 : Associations between antidiabetic and statin therapy and liver histology in patients with type 2 diabetes and non-alcoholic fatty liver disease

2015 ◽  
Vol 62 ◽  
pp. S749
Author(s):  
F. Nascimbeni ◽  
J. Aron-Wisniewsky ◽  
R. Pais ◽  
J. Tordjman ◽  
F. Charlotte ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Liver Disease ◽  
Fatty Liver ◽  
Statin Therapy ◽  
Fatty Liver Disease ◽  
Liver Histology ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease

Impact of Weight Regain on the Evolution of Non-alcoholic Fatty Liver Disease After Roux-en-Y Gastric Bypass: a 3-Year Follow-up

2018 ◽  
Vol 28 (10) ◽  
pp. 3131-3135 ◽  
Author(s):  
Laísa Simakawa Jimenez ◽  
Fábio Henrique Mendonça Chaim ◽  
Felipe David Mendonça Chaim ◽  
Murillo Pimentel Utrini ◽  
Martinho Antonio Gestic ◽  
...  
Keyword(s):  
Gastric Bypass ◽  
Liver Disease ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Weight Regain ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease

scholarly journals Simulation of gastric bypass effects on glucose metabolism and non-alcoholic fatty liver disease with the Sleeveballoon device

EBioMedicine ◽  
2019 ◽  
Vol 46 ◽  
pp. 452-462 ◽  
Author(s):  
James Casella-Mariolo ◽  
Lidia Castagneto-Gissey ◽  
Giulia Angelini ◽  
Andrea Zoli ◽  
Pierluigi Marini ◽  
...  
Keyword(s):  
Gastric Bypass ◽  
Liver Disease ◽  
Glucose Metabolism ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease

Role of neuropeptide Y gene variant (rs161477) in liver histology in obese patients with non-alcoholic fatty liver disease

2019 ◽  
Vol 66 (4) ◽  
pp. 217-222 ◽  
Author(s):  
Rocio Aller ◽  
Juan Jose López-Gomez ◽  
Olatz Izaola ◽  
David Primo ◽  
Daniel de Luis
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Neuropeptide Y ◽  
Fatty Liver Disease ◽  
Liver Histology ◽  
Obese Patients ◽  
Gene Variant ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease

Role of neuropeptide Y gene variant (rs161477) in liver histology in obese patients with non-alcoholic fatty liver disease

2019 ◽  
Vol 66 (4) ◽  
pp. 217-222
Author(s):  
Rocio Aller ◽  
Juan Jose López-Gomez ◽  
Olatz Izaola ◽  
David Primo ◽  
Daniel de Luis
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Neuropeptide Y ◽  
Fatty Liver Disease ◽  
Liver Histology ◽  
Obese Patients ◽  
Gene Variant ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease

scholarly journals Association between novel MRI-estimated pancreatic fat and liver histology-determined steatosis and fibrosis in non-alcoholic fatty liver disease

2013 ◽  
Vol 37 (6) ◽  
pp. 630-639 ◽  
Author(s):  
N. S. Patel ◽  
M. R. Peterson ◽  
D. A. Brenner ◽  
E. Heba ◽  
C. Sirlin ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Liver Histology ◽  
Alcoholic Fatty Liver ◽  
Pancreatic Fat ◽  
Alcoholic Fatty Liver Disease

682 Relationship between dietary intake and liver histology in non-alcoholic fatty liver disease

2006 ◽  
Vol 44 ◽  
pp. S251-S252 ◽  
Author(s):  
A. Federico ◽  
M. Trappoliere ◽  
E. Coppola ◽  
M. D'Auria ◽  
C. Del Vecchio Blanco ◽  
...  
Keyword(s):  
Liver Disease ◽  
Dietary Intake ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Liver Histology ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease
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