scholarly journals Insulin and free oestradiol are independent risk factors for benign prostatic hyperplasia

2008 ◽  
Vol 12 (2) ◽  
pp. 160-165 ◽  
Author(s):  
J Hammarsten ◽  
J-E Damber ◽  
M Karlsson ◽  
T Knutson ◽  
Ö Ljunggren ◽  
...  
2021 ◽  
Author(s):  
Euxu Xie ◽  
Xuelian Gu ◽  
Chen Ma ◽  
Li Guo ◽  
Man Li ◽  
...  

Abstract Objective To develop and validate a nomogram for predicting bladder calculi risk in patients with benign prostatic hyperplasia (BPH).Methods A total of 368 patients who underwent transurethral resection of the prostate (TURP) and had histologically proven BPH from January 2018 to January 2021 were retrospectively collected. Eligible patients were randomly assigned to the training and validation datasets. Least absolute shrinkage and selection operator (LASSO) regression was used to select the optimal risk factors. A prediction model was established based on the selected characteristics. The performance of the nomogram was assessed by calibration plots and the area under the receiver operating characteristic curve (AUROC). Furthermore, decision curve analysis (DCA) was used to determine the net benefit rate of of the nomogram. Results Among 368 patients who met the inclusion criteria, older age, a history of diabetes and hyperuricemia, longer intravesical prostatic protrusion (IPP)and larger prostatic urethral angulation (PUA) were independent risk factors for bladder calculi in patients with BPH. These factors were used to develop a nomogram, which had a good identification ability in predicting the risk of bladder calculi in patients, with AUROCs of 0.911 (95% CI: 0.876–0.945) in the training set and 0.884 (95% CI: 0.820–0.948) in the validation set. The calibration plot showed that the model had good calibration. Moreover, DCA indicated that the model had a goodclinical benefit. Conclusion We developed and internally validated the first nomogram to date to help physicians assess the risk of bladder calculi in patients with BPH, which may help physicians improve individual interventions and make better clinical decisions.


2012 ◽  
Vol 38 (2) ◽  
pp. 65-69
Author(s):  
Huseyin Cihan Demirel ◽  
Cevdet Serkan Gokkaya ◽  
Cuneyt Ozden ◽  
Binhan Kagan Aktas ◽  
Suleyman Bulut ◽  
...  

2008 ◽  
Vol 179 (4S) ◽  
pp. 526-526 ◽  
Author(s):  
Esther T Kok ◽  
Boris W Schouten ◽  
Arthur M Bohnen ◽  
Frans PMW Groeneveld ◽  
Siep Thomas ◽  
...  

2014 ◽  
Vol 15 (6) ◽  
pp. 763-767 ◽  
Author(s):  
Diego Abreu ◽  
Enrique Campos ◽  
Verónica Seija ◽  
Carlos Arroyo ◽  
Ruben Suarez ◽  
...  

2020 ◽  
Author(s):  
Xin Sun ◽  
Dexin Yu ◽  
Zhangjun Cao ◽  
Dongdong Xie ◽  
Liangkuan Bi

Abstract Background: To explore the risk factors that lead to the formation of bladder calculus in patients with benign prostatic hyperplasia (BPH). Methods: Retrospective study was performed between June 2017 and October 2019, 103 patients with BPH who underwent transurethral resection of the prostate (TURP) were included. Patients with BPH were divided into two groups: 32 patients with bladder calculus in group1 and 71 patients without bladder calculus in group2. Characteristics of both groups were compared and univariate and multivariate analyses were performed to investigate the association between BPH with or without bladder calculus. Results: There was no significant difference between the two groups regarding age, duration of BPH, body mass index (BMI), total prostate volume (TPV), total prostate-specific antigen (TPSA), International prostate symptom score (IPSS), serum albumin, hemoglobin, uric acid, urinary tract infection, diabetes, and hypertension. The patients' serum creatinine and acute urinary retention (AUR) were significantly lower, while intravesical prostatic protrusion (IPP) was significantly higher in group 1 than group 2. Multivariate analyses revealed that IPP and AUR were significant risk factors for the formation of bladder calculus in patients with BPH. For IPP, the receiver operating characteristic (ROC) curve showed that the cut-off value of the highest risk of the formation of bladder calculus was 11.5 mm. Conclusions: Our study indicated that IPP and AUR were independent risk factors that were closely linked with the incidence of bladder calculus in BPH patients.


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