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Mechanism for the activation of the anaplastic lymphoma kinase receptor
Nature
◽
10.1038/s41586-021-04140-8
◽
2021
◽
Author(s):
Andrey V. Reshetnyak
◽
Paolo Rossi
◽
Alexander G. Myasnikov
◽
Munia Sowaileh
◽
Jyotidarsini Mohanty
◽
...
Keyword(s):
Anaplastic Lymphoma Kinase
◽
Anaplastic Lymphoma
Download Full-text
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Cited By
References
Regulated expression of the Anaplastic Lymphoma Kinase (ALK) in cultured rat hepatic stellate cells during transdifferentiation into myofibroblasts
Zeitschrift für Gastroenterologie
◽
10.1055/s-2005-861584
◽
2005
◽
Vol 43
(01)
◽
Author(s):
M Antoine
◽
CG Tag
◽
W Wirz
◽
M Mavituna
◽
AM Gressner
◽
...
Keyword(s):
Hepatic Stellate Cells
◽
Anaplastic Lymphoma Kinase
◽
Stellate Cells
◽
Anaplastic Lymphoma
◽
Regulated Expression
Download Full-text
Anaplastic Lymphoma Kinase in Human Cancer
Critical Reviews™ in Oncogenesis
◽
10.1615/critrevoncog.v17.i2.10
◽
2012
◽
Vol 17
(2)
◽
pp. 123-143
◽
Cited By ~ 5
Author(s):
Christina Schonherr
◽
Bengt Hallberg
◽
Ruth Palmer
Keyword(s):
Anaplastic Lymphoma Kinase
◽
Human Cancer
◽
Anaplastic Lymphoma
Download Full-text
Study of TQ-B3139 Versus Crizotinib in the First Line Treatment of Subjects With Anaplastic Lymphoma Kinase (ALK) Positive Non-Small Cell Lung Cancer (NSCLC)
Case Medical Research
◽
10.31525/ct1-nct04009317
◽
2019
◽
Author(s):
Keyword(s):
Lung Cancer
◽
Small Cell Lung Cancer
◽
Anaplastic Lymphoma Kinase
◽
Small Cell
◽
Line Treatment
◽
Small Cell Lung
◽
First Line
◽
Anaplastic Lymphoma
◽
Alk Positive
◽
First Line Treatment
Download Full-text
Faculty Opinions recommendation of Anaplastic lymphoma kinase spares organ growth during nutrient restriction in Drosophila.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
◽
10.3410/f.12593957.791402800
◽
2012
◽
Author(s):
Savraj Grewal
Keyword(s):
Anaplastic Lymphoma Kinase
◽
Nutrient Restriction
◽
Organ Growth
◽
Anaplastic Lymphoma
Download Full-text
Faculty Opinions recommendation of The anaplastic lymphoma kinase in the pathogenesis of cancer.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
◽
10.3410/f.13353985.14725086
◽
2011
◽
Author(s):
Ruth Palmer
Keyword(s):
Anaplastic Lymphoma Kinase
◽
Anaplastic Lymphoma
Download Full-text
Faculty Opinions recommendation of Structure based drug design of crizotinib (PF-02341066), a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK).
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
◽
10.3410/f.12934957.14822055
◽
2012
◽
Author(s):
John Proudfoot
Keyword(s):
Drug Design
◽
Anaplastic Lymphoma Kinase
◽
Dual Inhibitor
◽
Structure Based Drug Design
◽
Anaplastic Lymphoma
◽
Mesenchymal Epithelial Transition Factor
◽
Factor C
◽
Mesenchymal Epithelial Transition
Download Full-text
Faculty Opinions recommendation of Structure based drug design of crizotinib (PF-02341066), a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK).
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
◽
10.3410/f.12934957.14323054
◽
2011
◽
Author(s):
John Lowe
Keyword(s):
Drug Design
◽
Anaplastic Lymphoma Kinase
◽
Dual Inhibitor
◽
Structure Based Drug Design
◽
Anaplastic Lymphoma
◽
Mesenchymal Epithelial Transition Factor
◽
Factor C
◽
Mesenchymal Epithelial Transition
Download Full-text
Faculty Opinions recommendation of Design of potent and selective inhibitors to overcome clinical anaplastic lymphoma kinase mutations resistant to crizotinib.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
◽
10.3410/f.718242031.793491637
◽
2014
◽
Author(s):
Jürgen Bajorath
Keyword(s):
Anaplastic Lymphoma Kinase
◽
Selective Inhibitors
◽
Anaplastic Lymphoma
Download Full-text
Faculty Opinions recommendation of Discovery of (10R)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a macrocyclic inhibitor of anaplastic lymphoma kinase (ALK) and c-ros oncogene 1 (ROS1) with preclinical brain exposure and broad-spectrum potency against ALK-resistant mutations.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
◽
10.3410/f.718385965.793501872
◽
2014
◽
Author(s):
Miles Congreve
◽
Mark Pickworth
Keyword(s):
Broad Spectrum
◽
Anaplastic Lymphoma Kinase
◽
Anaplastic Lymphoma
◽
Brain Exposure
Download Full-text
Identification of Novel Structurally Diverse Anaplastic Lymphoma Kinase Inhibitors Based on Pharmacophore Modeling, Virtual Screening and Molecular Docking
Combinatorial Chemistry & High Throughput Screening
◽
10.2174/1386207319666160801153455
◽
2016
◽
Vol 19
(9)
◽
pp. 691-704
Author(s):
Rong You
◽
Lu Zhou
◽
Liangliang Zhong
◽
Xiaoli Li
◽
Suwen Zhou
◽
...
Keyword(s):
Molecular Docking
◽
Virtual Screening
◽
Anaplastic Lymphoma Kinase
◽
Kinase Inhibitors
◽
Pharmacophore Modeling
◽
Anaplastic Lymphoma
Download Full-text
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