scholarly journals Relationship between obesity and development of erosive reflux disease: A mediation analysis of the role of cardiometabolic risk factors

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Hyuk Lee ◽  
Yaeji Lim ◽  
Sangah Chi ◽  
Yang Won Min ◽  
Byung-Hoon Min ◽  
...  
2016 ◽  
Vol 223 ◽  
pp. 352-359 ◽  
Author(s):  
Alberto Soriano-Maldonado ◽  
Virginia A. Aparicio ◽  
Francisco J. Félix-Redondo ◽  
Daniel Fernández-Bergés

Author(s):  
Caroline Brand ◽  
Clarice Maria de Lucena Martins ◽  
Arieli Fernandes Dias ◽  
Camila Felin Fochesatto ◽  
Antonio García-Hermoso ◽  
...  

Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 4176
Author(s):  
Dorota Drozdz ◽  
Julio Alvarez-Pitti ◽  
Małgorzata Wójcik ◽  
Claudio Borghi ◽  
Rosita Gabbianelli ◽  
...  

Obesity has become a major epidemic in the 21st century. It increases the risk of dyslipidemia, hypertension, and type 2 diabetes, which are known cardiometabolic risk factors and components of the metabolic syndrome. Although overt cardiovascular (CV) diseases such as stroke or myocardial infarction are the domain of adulthood, it is evident that the CV continuum begins very early in life. Recognition of risk factors and early stages of CV damage, at a time when these processes are still reversible, and the development of prevention strategies are major pillars in reducing CV morbidity and mortality in the general population. In this review, we will discuss the role of well-known but also novel risk factors linking obesity and increased CV risk from prenatal age to adulthood, including the role of perinatal factors, diet, nutrigenomics, and nutri-epigenetics, hyperuricemia, dyslipidemia, hypertension, and cardiorespiratory fitness. The importance of ‘tracking’ of these risk factors on adult CV health is highlighted and the economic impact of childhood obesity as well as preventive strategies are discussed.


BMC Medicine ◽  
2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Aurore Fayosse ◽  
Dinh-Phong Nguyen ◽  
Aline Dugravot ◽  
Julien Dumurgier ◽  
Adam G. Tabak ◽  
...  

Nutrients ◽  
2018 ◽  
Vol 10 (8) ◽  
pp. 1066 ◽  
Author(s):  
Lide Arenaza ◽  
Victoria Muñoz-Hernández ◽  
María Medrano ◽  
Maddi Oses ◽  
Maria Amasene ◽  
...  

There is a general belief that having breakfast is an important healthy lifestyle factor; however, there is scarce evidence on the influence of breakfast quality and energy density on cardiometabolic risk in children, as well as on the role of physical activity in this association. The aims of this paper were (i) to examine the associations of breakfast quality and energy density from both solids and beverages with cardiometabolic risk factors, and (ii) to explore whether physical activity levels may attenuate these relationships in children with overweight/obesity from two projects carried out in the north and south of Spain. Breakfast consumption, breakfast quality index (BQI) score, BEDs/BEDb (24 h-recalls and the KIDMED questionnaire), and physical activity (PA; accelerometry) were assessed, in 203 children aged 8–12 years who were overweight or obese. We measured body composition (Dual X-ray Absorptiometry), uric acid, blood pressure, lipid profile, gamma-glutamyl-transferase (GGT), glucose, and insulin, and calculated the HOMA and metabolic syndrome z-score. The BQI score was inversely associated with serum uric acid independently of a set of relevant confounders (β = −0.172, p = 0.028), but the relationship was attenuated after further controlling for total PA (p < 0.07). BEDs was positively associated with total and HDL cholesterol, and systolic blood pressure regardless of confounders (all p < 0.05), while BEDb was positively associated with HOMA in either active/inactive children (all p < 0.03). In conclusion, higher breakfast quality and lower breakfast energy density should be promoted in overweight/obesity children to improve their cardiometabolic health.


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