Exploration and application of a highly sensitive bis(salamo)-based fluorescent sensor for B4O72− in water-containing systems and living cells

A highly sensitive and selective fluorescent probe (FS) is based on a fluoride-specific desilylation reaction to yield a significant green fluorescence enhancement.

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Simple naphthalimide-based fluorescent sensor for highly sensitive and selective detection of Cd2+and Cu2+in aqueous solution and living cells

Dalton Transactions ◽

10.1039/c2dt32279j ◽

2013 ◽

Vol 42 (5) ◽

pp. 1827-1833 ◽

Cited By ~ 68

Author(s):

Wei Wang ◽

Qian Wen ◽

Yue Zhang ◽

Xiaoliang Fei ◽

Yaoxian Li ◽

...

Keyword(s):

Aqueous Solution ◽

Fluorescent Sensor ◽

Living Cells ◽

Selective Detection ◽

Highly Sensitive

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A Novel Highly Sensitive and Selective Fluorescent Sensor for Imaging Copper (II) in Living Cells

Journal of Fluorescence ◽

10.1007/s10895-014-1419-7 ◽

2014 ◽

Vol 24 (4) ◽

pp. 1331-1336 ◽

Cited By ~ 12

Author(s):

Chen Zhou ◽

Yan Song ◽

Ning Xiao ◽

Yapeng Li ◽

Jiayuan Xu

Keyword(s):

Fluorescent Sensor ◽

Living Cells ◽

Highly Sensitive

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A highly sensitive and selective turn-on fluorescent sensor for dihydrogen phosphate in living cells

Sensors and Actuators B Chemical ◽

10.1016/j.snb.2017.03.052 ◽

2017 ◽

Vol 247 ◽

pp. 791-796 ◽

Cited By ~ 16

Author(s):

Kun-Peng Wang ◽

Si-Jie Zhang ◽

Cheng-Dong Lv ◽

Hui-Shi Shang ◽

Zhi-Hui Jin ◽

...

Keyword(s):

Fluorescent Sensor ◽

Living Cells ◽

Dihydrogen Phosphate ◽

Turn On ◽

Highly Sensitive

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A novel highly sensitive and selective fluorescent sensor for imaging mercury(ii) in living cells

RSC Advances ◽

10.1039/c4ra03908d ◽

2014 ◽

Vol 4 (63) ◽

pp. 33614 ◽

Cited By ~ 14

Author(s):

Chen Zhou ◽

Yan Song ◽

Yapeng Li

Keyword(s):

Fluorescent Sensor ◽

Living Cells ◽

Highly Sensitive

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A Simple and Highly Sensitive Turn-on Schiff Base Type Naked-eye Fluorescent Sensor for Aluminum Ion in Living Cells

Acta Chimica Slovenica ◽

10.17344/acsi.2018.4755 ◽

2019 ◽

pp. 792-801

Author(s):

Sedat Keskin ◽

Mevlut Bayrakci

Keyword(s):

Schiff Base ◽

Fluorescent Sensor ◽

Living Cells ◽

Aluminum Ion ◽

Naked Eye ◽

Turn On ◽

Highly Sensitive

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Fluorescence ratio imaging of dynamic intracellular ionic signals

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100102298 ◽

1988 ◽

Vol 46 ◽

pp. 42-43

Author(s):

R. Y. Tsien ◽

A. Minta ◽

M. Poenie ◽

J.P.Y. Kao ◽

A. Harootunian

Keyword(s):

Binding Sites ◽

Living Cells ◽

Molecular Engineering ◽

Ph Indicators ◽

Highly Sensitive ◽

Fluorescence Ratio Imaging ◽

Ratio Imaging ◽

Technical Advances ◽

Indicator Dyes ◽

Fluorescein Dyes

Recent technical advances now enable the continuous imaging of important ionic signals inside individual living cells with micron spatial resolution and subsecond time resolution. This methodology relies on the molecular engineering of indicator dyes whose fluorescence is strong and highly sensitive to ions such as Ca2+, H+, or Na+, or Mg2+. The Ca2+ indicators, exemplified by fura-2 and indo-1, derive their high affinity (Kd near 200 nM) and selectivity for Ca2+ to a versatile tetracarboxylate binding site3 modeled on and isosteric with the well known chelator EGTA. The most commonly used pH indicators are fluorescein dyes (such as BCECF) modified to adjust their pKa's and improve their retention inside cells. Na+ indicators are crown ethers with cavity sizes chosen to select Na+ over K+: Mg2+ indicators use tricarboxylate binding sites truncated from those of the Ca2+ chelators, resulting in a more compact arrangement of carboxylates to suit the smaller ion.

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