A highly selective turn-on fluorescent sensor for fluoride and its application in imaging of living cells

2014 ◽  
Vol 38 (12) ◽  
pp. 6198-6204 ◽  
Author(s):  
Jiun-Ting Yeh ◽  
Parthiban Venkatesan ◽  
Shu-Pao Wu

A highly sensitive and selective fluorescent probe (FS) is based on a fluoride-specific desilylation reaction to yield a significant green fluorescence enhancement.

Talanta ◽  
2020 ◽  
Vol 209 ◽  
pp. 120548 ◽  
Author(s):  
Yilin Zhu ◽  
Kangnan Wang ◽  
Xiangwen Wu ◽  
Yanan Sun ◽  
Xiangshuo Gong ◽  
...  

RSC Advances ◽  
2015 ◽  
Vol 5 (129) ◽  
pp. 107012-107019 ◽  
Author(s):  
Jianfei Tian ◽  
Xiaxia Yan ◽  
Hui Yang ◽  
Fuli Tian

Quinoline Schiff base L exhibits a more than 38-fold fluorescence enhancement after addition of Al3+ ions at an excitation wavelength of 373 nm, and shows a high selectivity for Al3+ over other metal ions.


RSC Advances ◽  
2019 ◽  
Vol 9 (51) ◽  
pp. 29856-29863 ◽  
Author(s):  
Suman Srivastava ◽  
Neha Thakur ◽  
Ashutosh Singh ◽  
Poonam Shukla ◽  
Vipin Kumar Maikhuri ◽  
...  

A new fluorescent sensor 5 having fused imidazopyridine scaffold has been synthesized via cascade cyclization. It exhibits highly sensitive and selective detection of Fe3+ (‘turn-on’) and Hg2+ (‘turn-off’) in vitro and in HeLa cells.


2016 ◽  
Vol 8 (11) ◽  
pp. 2420-2426 ◽  
Author(s):  
Youming Shen ◽  
Xiangyang Zhang ◽  
Youyu Zhang ◽  
Chunxiang Zhang ◽  
Junling Jin ◽  
...  

A novel and simple turn-on fluorescent probe bearing NBD and benzaldehyde fragments for the rapid optical sensing of biothiols has been designed and synthesized.


2017 ◽  
Vol 9 (5) ◽  
pp. 864-870 ◽  
Author(s):  
Jing Guo ◽  
Zhixiang Zhang ◽  
Ziyu Kuai ◽  
Rui Wang ◽  
Qingbiao Yang ◽  
...  

A novel turn-on fluorescent sensor PIPH based on changes in the internal conformation between the ground and first excited state.


Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3352
Author(s):  
Yingying Zuo ◽  
Yang Jiao ◽  
Chunming Ma ◽  
Chunying Duan

Hydrogen peroxide (H2O2) plays an important role in the human body and monitoring its level is meaningful due to the relationship between its level and diseases. A fluorescent sensor (CMB) based on coumarin was designed and its ability for detecting hydrogen peroxide by fluorescence signals was also studied. The CMB showed an approximate 25-fold fluorescence enhancement after adding H2O2 due to the interaction between the CMB and H2O2 and had the potential for detecting physiological H2O2. It also showed good biocompatibility and permeability, allowing it to penetrate cell membranes and zebrafish tissues, thus it can perform fluorescence imaging of H2O2 in living cells and zebrafish. This probe is a promising tool for monitoring the level of H2O2 in related physiological and pathological research.


2017 ◽  
Vol 247 ◽  
pp. 791-796 ◽  
Author(s):  
Kun-Peng Wang ◽  
Si-Jie Zhang ◽  
Cheng-Dong Lv ◽  
Hui-Shi Shang ◽  
Zhi-Hui Jin ◽  
...  

Molecules ◽  
2019 ◽  
Vol 24 (3) ◽  
pp. 411 ◽  
Author(s):  
Xiaohua Ma ◽  
Yuanqiang Hao ◽  
Jiaxiang Liu ◽  
Guoguang Wu ◽  
Lin Liu

A new green-emitting fluorescent probe 1 was developed for biothiol detection. The sensing mechanism was considered to be biothiol-induced cleavage of the 2,4-dinitrobenzene- sulfonate group in probe 1 and resulting inhibition of the probe’s photoinduced electron transfer (PET) process. Probe 1 exhibited favorable properties such as excellent selectivity, highly sensitive (0.12 µM), large Stokes shift (117 nm) and a remarkable turn-on fluorescence signal (148-fold). Furthermore, confocal fluorescence imaging indicated that probe 1 was membrane-permeable and suitable for visualization of biothiols in living A549 cells.


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