scholarly journals Comparison of heads up three dimensional visualization system to conventional microscope in retinopathy of prematurity related tractional retinal detachment

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Abdulrahman AlZaid ◽  
Wael A. Alsakran ◽  
Sulaiman M. Alsulaiman ◽  
Marco Mura
Keyword(s):  
Retinal Detachment ◽  
Success Rate ◽  
Retinopathy Of Prematurity ◽  
3D Visualization ◽  
Three Dimensional ◽  
Conventional Group ◽  
Tractional Retinal Detachment ◽  
Visualization System ◽  
Advantages And Disadvantages ◽  
Conventional Microscope

AbstractTo report the outcomes, advantages and disadvantages of a heads-up three-dimensional (3D) visualization system compared to the conventional microscope in pediatric tractional retinal detachment (TRD) surgery secondary to advanced stage retinopathy of prematurity (ROP). Medical records of patients with ROP stage 4 or 5 who underwent surgery for tractional retinal detachment at King Khaled Eye Specialist Hospital between September 2017 and July 2019 were identified and reviewed. Eyes were divided into 2 groups, eyes that underwent surgery with a 3D heads-up platform (3D group) and eyes that underwent surgery with a conventional microscope (conventional group). Data were collected on neonatal history, visual acuity, intraoperative complications and success rates between groups.Eighteen eyes of 14 patients who underwent surgical repair of TRD related to ROP. Postoperative outcomes were compared between 10 eyes (7 patients) in the 3D group and 8 eyes (7 patients) in the conventional group There was no statistically significant difference in success rate between both groups (75% conventional group vs 70% 3D group). Partial or complete reattachment was achieved in 7 eyes in 3D group compared to 6 eyes in conventional group. Lower postmenstrual age at the time of the first surgery and presence of retinal breaks were associated with poorer surgical outcome. Heads up 3D visualization system is feasible in tractional retinal detachment related to ROP with similar success rate and no increased risk of complications when compared to conventional microscope. This system may be advantageous in advanced pediatric tractional retinal detachment surgeries.

A novel three-dimensional visualization system revealed an essential adaptive angiogenic response during the early phase of pulmonary hypertension

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
T Fujiwara ◽  
N Takeda ◽  
M Hatano ◽  
S Nishimura ◽  
I Komuro
Keyword(s):  
Pulmonary Hypertension ◽  
Early Phase ◽  
3D Visualization ◽  
Hypoxia Inducible Factor ◽  
Three Dimensional ◽  
Right Heart Failure ◽  
Wall Thickening ◽  
Funding Source ◽  
Vegf Expression ◽  
Visualization System

Abstract Background Pulmonary hypertension (PH) is characterized by increased pulmonary vascular resistance and right heart failure with progressive narrowing or occlusion of the pulmonary artery. However, the assessment of vascular remodeling is mostly limited to averaged increases in wall thickening, and even the role of vascular endothelial growth factor (VEGF), remains incompletely understood; Although abundantly expressed VEGF is expected to elicit angio-obliteration and the knockout of hypoxia inducible factor (HIF) prevents PH in mice, VEGF inhibitor Sugen exacerbates hypoxia (Hx)-induced PH model, which is referred to as VEGF paradox. Purpose To analyze three-dimensional (3D) spatiotemporal changes of pulmonary microstructure and function, which reflect the disease activity and lead to resolve the paradox. Methods and results We developed a novel 3D visualization system of microstructural networks in whole mouse organ with single-cell resolution, using combined tissue clearing technique called CUBIC and multiphoton excitation microscope. The system enabled the simultaneous 3D evaluation of microvascular structure, invaded macrophages and fibrosis with effective penetration of several mm (whole organ). Three-dimensional observations of PH mice models including Hx, Sugen/Hx, and human-like Alk1+/− hereditary PH models, revealed that not only inward (negative) microvessel remodeling with stenosis, but also marked elongation of microvascular ECs, was evident except Sugen/Hx model at the early phase, which had not been detected by 2D histological sections. Comparable transcriptome analysis revealed that PGC1α, which regulates HIF-independent VEGF expression and angiogenesis, plays an important role in the characteristic response for mitochondrial and microvascular maintenance. PGC1α was up-regulated in the early phage in Hx and Alk1+/− PH models with microvascular angiogenetic change, whereas Sugen/Hx-model did not increase PGC1α expression and did not show microvascular remodeling. Furthermore pulmonary ECs-specific PGC1α-deficient mice exacerbated Hx-PH model with decreased VEGF expression and microvessel density, and administration of Baicalin, a flavonoid enhancing PGC1α expression, ameliorated Hx-PH model with increased VEGF expression. Conclusions The 3D visualization system disclosed an unexpected change of angiogenic microvascular structure in the early phage of PH, which is regulated by EC PGC1α. Microvascular angiogenesis which is induced by up-regulation in PGC1α -VEGF pathway is a crucial factor for compensation of PH in the early phase, which provides a potential novel therapeutic target for PH. Figure 1 Funding Acknowledgement Type of funding source: Public grant(s) – National budget only. Main funding source(s): JSJP

Cognitive workload, complications and visual outcomes of phacoemulsification cataract surgery: Three-dimensional versus conventional microscope

2021 ◽  
pp. 112067212110620
Author(s):  
Aditya Kelkar ◽  
Jai Kelkar ◽  
Yogesh Chougule ◽  
Mounika Bolisetty ◽  
Priyanka Singhvi
Keyword(s):  
Cataract Surgery ◽  
Three Dimensional ◽  
Posterior Chamber ◽  
Dimensional System ◽  
Cognitive Workload ◽  
Visualization System ◽  
Visual Outcomes ◽  
Conventional Microscope ◽  
Three Dimensional System ◽  
Phacoemulsification Cataract Surgery

Purpose To compare the surgical workload, complications, and visual outcomes using the three-dimensional visualization system with the conventional microscope in phacoemulsification cataract surgery. Design Prospective, non-randomized, open-label interventional study. Methods All patients underwent phacoemulsification cataract surgery using the three-dimensional visualization system or conventional microscope. Results Of the 203 eyes, 80 underwent surgery with the three-dimensional system while 123 underwent with the conventional microscope. No difference was noted in the total surgical duration, complication rates, and visual outcomes between the two groups. However, capsulorhexis was significantly faster using the conventional microscope while posterior chamber intraocular lens insertion was quicker using the three-dimensional system. In terms of cognitive workload comparison, no difference was seen in the surgeons’ heart rate, oxygen saturation levels, and surgery task load index total workload score and workload score for all six dimensions of the questionnaire, between the three-dimensional system and conventional microscope groups. As compared to baseline, the heart rate increased significantly during all surgical steps and at the end in both groups. When compared to baseline, the oxygen saturation levels were significantly raised during capsulorhexis, irrigation, and aspiration and posterior chamber intraocular lens insertion and at the end of the surgery in the three-dimensional group and during incision and at the end of the surgery in the conventional microscope group. Conclusions The duration of surgery, complications, and visual acuity outcomes remain unaffected while performing phacoemulsification cataract surgeries with the three-dimensional viewing system when compared to the conventional microscopes. Moreover, the surgeons’ cognitive workload too remains unaffected while utilizing this revolutionary three-dimensional surgical technology.

Information Visualization with Text Data Mining for Knowledge Discovery Tools in Bioinformatics

2005 ◽  
Vol 277-279 ◽  
pp. 259-265
Author(s):  
Jin Ah Park ◽  
Chang Su Lee ◽  
Jong C. Park
Keyword(s):  
Data Mining ◽  
3D Visualization ◽  
Three Dimensional ◽  
Mitogen Activated Protein Kinase ◽  
Text Data ◽  
Text Data Mining ◽  
Visualization System ◽  
Source Data ◽  
Mitogen Activated Protein ◽  
Available Information

An abundant amount of information is produced in the digital domain, and an effective information extraction (IE) system is required to surf through this sea of information. In this paper, we show that an interactive visualization system works effectively to complement an IE system. In particular, three-dimensional (3D) visualization can turn a data-centric system into a user-centric one by facilitating the human visual system as a powerful pattern recognizer to become a part of the IE cycle. Because information as data is multidimensional in nature, 2D visualization has been the preferred mode. However, we argue that the extra dimension available for us in a 3D mode provides a valuable space where we can pack an orthogonal aspect of the available information. As for candidates of this orthogonal information, we have considered the following two aspects: 1) abstraction of the unstructured source data, and 2) the history line of the discovery process. We have applied our proposal to text data mining in bioinformatics. Through case studies of data mining for molecular interaction in the yeast and mitogen-activated protein kinase pathways, we demonstrate the possibility of interpreting the extracted results with a 3D visualization system.

A Research on Digital City Three-Dimensional Visualization System Based on Skyline

2014 ◽  
Vol 580-583 ◽  
pp. 2745-2748 ◽  
Author(s):  
Hong Bao Dai ◽  
Xiang Jun Yue ◽  
Ji Ying Xu
Keyword(s):  
3D Visualization ◽  
System Development ◽  
Three Dimensional ◽  
Basic Operation ◽  
Digital City ◽  
Landscape Model ◽  
Human Beings ◽  
Visualization System ◽  
Aerial Photos ◽  
Terrain Model

As an important living place for human beings, city is regarded as a main place for the birth, spread and development of human civilization. This paper, based on the principle of system development and combining with the need of building “Digital City”, makes an overall design of the “Digital City” 3D visualization system. Firstly, a 3D ground objects model, i.e. .x files, is made through inputting the ground objects of the experimental area into 3DSMAX, then, the .x files are converted to .xpc files in order to achieve a better displaying effect in producing a 3D landscape. Secondly, the author makes corresponding pre-processing to the aerial photos, satellite images, topographic data, digital elevation models and a variety of vector geographic data, and then superimposes and loads these data into Terra Builder module of Skyline software, which generates 3D topography landscape, that is, .MPT files and forms the terrain database required in Terra Explorer Pro software. Next, a 3D landscape is preliminarily established by inputting the 3D terrain model and the 3D ground objects model, i.e. .MPT files and .xpl files, in Terra Explorer Pro, and by editing a real and accurate 3D geographic model and a real Digital City 3D landscape model, that is, FLY files, are respectively formed. Finally, on the basis of the 3D landscape model, the system is developed by using Visual Basic + TerraDeveloper and the basic operation of 3D, spatial analysis, visible analysis and other basic functions are preliminarily achieved

scholarly journals Use of the heads-up NGENUITY 3D Visualization System for vitreoretinal surgery: a retrospective evaluation of outcomes in a French tertiary center

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Pierre Kantor ◽  
Frédéric Matonti ◽  
Fanny Varenne ◽  
Vanessa Sentis ◽  
Véronique Pagot-Mathis ◽  
...  
Keyword(s):  
3D Visualization ◽  
Three Dimensional ◽  
Vitreoretinal Surgery ◽  
Retrospective Evaluation ◽  
Visualization System ◽  
Surgical Microscope ◽  
Tertiary Center ◽  
Visualization Systems ◽  
Conventional Microscopy ◽  
Anatomical Outcomes

AbstractHeads-up three-dimensional (3D) surgical visualization systems allow ophthalmic surgeons to replace surgical microscope eyepieces with high-resolution stereoscopic cameras transmitting an image to a screen. We investigated the effectiveness and safety of the heads-up NGENUITY 3D Visualization System in a retrospective evaluation of 241 consecutive vitreoretinal surgeries performed by the same surgeon using conventional microscopy (CM group) over a 1-year period versus the NGENUITY System (3D group) over a consecutive 1-year period. We included for study vitreoretinal surgeries for treatment of retinal detachment (RD) (98 surgeries), macular hole (MH) (48 surgeries), or epiretinal membrane (ERM) (95 surgeries). A total of 138 and 103 eyes were divided into 3D and CM groups, respectively. We found no differences in 3-month postoperative rates of recurrence of RD (10% versus 18%, p = 0.42), MH closure (82% versus 88%, p = 0.69), or decrease in central macular thickness of ERMs (134 ± 188 µm versus 115 ± 105 µm, p = 0.57) between the 3D and CM groups, respectively. Surgery durations and visual prognosis were also similar between both groups. We consolidate that the NGENUITY System is comparable in terms of visual and anatomical outcomes, giving it perspectives for integration into future robotized intervention.

Cost-Effective 3D Stereo Visualization for Creative Learning

2019 ◽  
pp. 239-251
Author(s):  
R. S. Kamath ◽  
R. K. Kamat
Keyword(s):  
3D Visualization ◽  
Learning Experience ◽  
Three Dimensional ◽  
Cost Effective ◽  
Visualization Tool ◽  
Visualization System ◽  
Creative Learning ◽  
Technological Platform ◽  
Artificial World

Using a pedagogic case study of development of three dimensional (3D) stereo visualization suite, in this chapter, the authors exemplify the emerging paradigm shift of educational technology progressively from simulation to virtual reality (VR). The authors present the transformation of higher education archetypes using VR, which is poised to create a whole new meaning for the young learners. It mainly personifies the computer-generated three-dimensional environments that give the viewer an intense feeling of being immersed in an artificial world. The authors clearly demonstrate exploiting a 3D stereo visualization system in learning environment for bringing in an experiential learning experience of real industrial scenario in the classroom itself. They present the design and development of 3D visualization tool that embodies complex datasets in virtual environment. Thus, the chapter epitomizes the significance of VR in edification that impacts creative learning without using real tools on a less sophisticated technological platform.

scholarly journals 3D Interactive Visualization Method of Urban Waterlogging Based on Cesium

2019 ◽  
Vol 1 ◽  
pp. 1-1
Author(s):  
Xu Zhang ◽  
Wei Zhou ◽  
Jie Shen ◽  
Lukáš Herman ◽  
Yixian Du
Keyword(s):  
3D Visualization ◽  
Three Dimensional ◽  
Interactive Visualization ◽  
Model Parameters ◽  
Visualization Method ◽  
Process Data ◽  
Visualization System ◽  
Simulation Based ◽  
Simulation Results ◽  
3D Scene

<p><strong>Abstract.</strong> Urban waterlogging, as a common natural disaster in China, seriously restricted the development of society. Nowadays, while the computer technology is developing continuously, the urban waterlogging model is also constantly improved. These models can simulate the process of urban waterlogging, but the simulation results are not intuitive. So it is difficult for users to understand how the model works. Therefore, it is important to find a way to show the simulation results so that people can see the waterlogging simulation intuitively. Cesium, as a three-dimensional visualization platform, can reproduce the process of the urban waterlogging. It will make sense if we could show the simulation results on the Cesium platform. Nowadays, many studies focus on both urban waterlogging and visualization methods. However, there are fewer studies on the combination of the two, especially the interactive visualization of urban waterlogging under parameter adjustment. Therefore, this paper mainly focuses on urban three-dimensional interactive visualization method based on Cesium.</p><p>On the one hand, the three-dimensional visualization of the urban waterlogging simulation facilitates the intuitive expression of the simulation results. Without visualization, the results of the simulation are only some complicated and unintuitive figures for most non-experts. On the other hand, visualization based on the Cesium platform can better adapt to the cross-platform application. It can better meet the needs of different terminal devices of different users for the visualization platform, so that users can obtain the disaster information more accurately, consistently and intuitively. It is conducive for management departments to respond to sudden disasters more quickly and efficiently.</p><p>This research aims to propose a three-dimensional dynamic interactive visualization method for urban waterlogging. Particularly, we hope to find out how to integrate urban waterlogging model and 3D visualization platform. With this 3D visualization platform, we can combine the advantages of the SWMM (Storm Water Management Model) and Cesium platform. Using this platform, it will be easier and more effective to respond to disasters for the masses and management departments.</p><p>The following two issues are resolved in this study: i) How do model parameters affect the urban waterlogging simulation and visualization results? ii) How to integrate SWMM and Cesium 3D visualization platform?</p><p>In order to address the above research objectives, we will apply the following methodologies: i) We will analyse the parameters of the SWMM for the urban waterlogging visualization. Under the premise of understanding the development process of the urban waterlogging, we will analyse the modelling principle of the urban waterlogging, the mechanism of each part of the model separately. Then, we will find out the method of determining the model parameters of urban waterlogging and its influence on the simulation visualization results. ii) We will study integration methods of urban waterlogging model and 3D visualization platform. We will analyse the mechanism and process of urban waterlogging. We will also calculate the urban waterlogging process data by the SWMM, and establish a three-dimensional visualization platform by the node.js and Cesium, which can dynamically show the process of urban waterlogging. iii) We will complete the design and implementation of the interactive visualization platform of urban waterlogging. According to the above research, taking the Xianlin Campus of Nanjing Normal University as an example, we will build a dynamic interactive visualization system of urban waterlogging simulation based on Cesium. We will also verify the effectiveness of the system by comparing it with actual flood situation.</p><p>With this study, we expect to answer how model parameters affect the urban waterlogging simulation and visualization results. As expected results, we plan to build an interactive visualization system of urban waterlogging simulation based on Cesium, publish the flood calculation results into the 3D scene. This will make urban waterlogging process shown in the 3D scene. This visualization system is designed for different users, including specialists, government and individual. It means that you can use the system easily even if you are non-cartographers or non-IT-specialists.</p>

scholarly journals Anatomical Study of the Hepatic Veins in Segment 4 of the Liver Using Three-Dimensional Visualization

2021 ◽  
Vol 8 ◽  
Author(s):  
Jun Zhang ◽  
Xiaochao Guo ◽  
Qilu Qiao ◽  
Jianxun Zhao ◽  
Xin Wang
Keyword(s):  
Hepatic Vein ◽  
3D Visualization ◽  
Venous Blood ◽  
Three Dimensional ◽  
Morphological Characteristics ◽  
Hepatic Veins ◽  
Hepatic Surgery ◽  
Visualization System ◽  
Vein System ◽  
Visualization Technology

Objective: The current study aimed to examine the anatomical structure of the hepatic vein of segment IV liver (S4) of the liver using three-dimensional (3D) visualization technology in order to explore the surgical value of the middle hepatic vein (MHV) manipulation and highlight the importance of current research in hepatic surgery.Methods: Between January 2014 and December 2019, 52 patients with abdominal diseases(not including hepatic disease) were selected for multiphasic computed tomography-enhanced scans of the upper abdomen. A 3D visualization system was utilized to display the structural details of the hepatic veins in S4 of their livers. Couinaud's eight-segment classification system was used to denote the liver' sections.Results: The constructed 3D model clearly displayed vascular morphological characteristics and their location in the liver, hepatic artery and vein system, and portal vein system. Of the 52 patients, 43 had an umbilical fissure vein (UFV) (82.7%), 19 had an accessory S4 liver vein (36.5%), 16 had both a UFV (30.8%) and an accessory S4 liver vein, and 6 had neither (11.5%). A total of 79% of the patients with a UFV and 74.2% of those with an accessory S4 liver vein had venous blood returning into the left hepatic vein.Conclusion: 3D visualization technology was used to determine hepatic venous return of S4 hepatic veins and was found to improve the safety of evaluation in hepatic surgery.

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