scholarly journals The Tri-ponderal Mass Index is associated with adiposity in adolescent type 2 diabetes mellitus: a cross-sectional analysis

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Haifa Alfaraidi ◽  
Brandy Wicklow ◽  
Allison B. Dart ◽  
Elizabeth Sellers ◽  
Jonathan McGavock ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Type 2 Diabetes Mellitus ◽  
Secondary Data ◽  
P Value ◽  
Z Score ◽  
Cross Sectional ◽  
The Metabolic Syndrome

AbstractPediatric type 2 diabetes mellitus (T2DM) patients are often overweight or obese, yet there are no validated clinical measures of adiposity to stratify cardiometabolic risk in this population. The tri-ponderal mass index (TMI, kg/m3) has recently been reported as a measure of adiposity in children, but there has been no validation of the association of TMI with adiposity in pediatric T2DM. We hypothesized that in children with T2DM, the TMI can serve as a more accurate measure of adiposity when compared to BMI z-score, and that it is associated with components of the metabolic syndrome. This is a cross-sectional secondary data analysis from the Improving Renal Complications in Adolescents with Type 2 Diabetes Through REsearch (iCARE) study (n = 116, age 10.20–17.90 years). Spearman’s correlations and multivariable regression were used in the analyses. When compared to DXA, TMI demonstrated significant correlation with total adiposity versus BMI z-score (TMI r = 0.74, p-value < 0.0001; BMI z-score r = − 0.08, p-value 0.403). In regression analyses, TMI was associated with WHtR (B = 35.54, 95% CI 28.81, 42.27, p-value < 0.0001), MAP dipping (B = 1.73, 95% CI 0.12, 3.33, p-value = 0.035), and HDL (B = − 5.83, 95% CI − 10.13, − 1.54, p-value = 0.008). In conclusion, TMI is associated with adiposity and components of the metabolic syndrome in pediatric T2DM patients.

scholarly journals Prevalence of metabolic syndrome in non-obese newly detected Type-2 diabetes Mellitus

2016 ◽  
Vol 9 (1) ◽  
pp. 26
Author(s):  
Mahbooba Akhter ◽  
Afsana Ahmed ◽  
Mahbubor Rahman ◽  
Roksana Malek ◽  
Azmeri Alam ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Type 2 Diabetes Mellitus ◽  
Preventive Strategy ◽  
Cross Sectional ◽  
The Metabolic Syndrome ◽  
Type 2 Dm ◽  
Medical University

<p><strong>B</strong><strong>ackground</strong><strong>: </strong>The metabolic syndrome is driving twin global epidemics; type 2 diabetes mellitus and cardiovascular disease. There is an overwhelming moral, medical, and economic imperative to identify those individuals with metabolic syndrome. Regarding this issue, non obese individuals are given less attention and ultimately situation becomes grievous therefore.</p><p><strong>Ob</strong><strong>j</strong><strong>ective</strong><strong>: </strong>To assess the prevalence of metabolic syndrome in non–obese newly detected type 2 DM patient. Method: This cross sectional analytical study was carried out in the department of Biochemistry, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. Total 209 cases (165 male &amp; 44 female) were selected from BIRDEM. Statistical analysis and data management were carried out using the SPSS (Version 12.0).</p><p><strong>R</strong><strong>esult</strong><strong>: </strong>In this study, prevalence rates of metabolic syndrome were 60.3% (53.3% male, 86.4% female), 58.9% (57.0% male, 65.9% female) and 26.3% (15.8% male, 65.9% female) according to modified National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP III), modified WHO &amp; IDF criteria respectively.</p><p><strong>Conclusion</strong><strong>: </strong>Prevalence of metabolic syndrome in non-obese newly detected Type 2 DM is very high &amp; Prevalence of metabolic syndrome in non-obese newly detected Type 2 DM found significantly higher in female than male. Adequate realistic steps of preventive strategy are of urgent need to combat this high prevalence of metabolic syndrome in non-obese diabetic people.</p>

PREVALENCE OF HYPERTENSION AMID PATIENTS WITH TYPE-2 DIABETES MELLITUS- AT A TERTIARY LEVEL HOSPITAL IN CENTRAL INDIA

2021 ◽  
pp. 57-59
Author(s):  
Hakimuddin Malvi ◽  
Syed Maqsood Husain
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Central India ◽  
P Value ◽  
Tertiary Level ◽  
Cross Sectional ◽  
Study Results ◽  
Level Hospital

Background: India has been recognized as the diabetes capital of the world by the year of 2025 Hypertension is a signicant danger factor for cardiovascular infection, stroke and ischemic coronary illness. Objective: The aim of this paper is prevalence of hypertension amid patients with type 2 diabetes mellitus- at a tertiary level hospital in central India. Methods: Present work is hospital based cross-sectional study was conduct in Chirayu Medical College & Hospital, Bhopal. The study population consisted of total 300 subjects. Data obtained directly from patients and patients medical les, and the following data were included in the study . Results: The results showed that the after using chi-square test we found that hypertension was signicantly higher p value(<0.05) among female patients (69%),patients with long duration diabetes (77%)10 years and more, also it was signicantly higher among patients with current smokers (69%). Conclusion: In this study the prevalence of hypertension is increasing in patient with T2DM. Hypertension was the most danger factor for micro vascular and macro vascular confusion of T2DM.

scholarly journals Advantages of therapy with sodium glucose cotransporter type 2 inhibitors in patients with type 2 diabetes mellitus in combination with hyperuricemia and gout

2020 ◽  
Vol 92 (5) ◽  
pp. 110-118 ◽  
Author(s):  
T. S. Panevin ◽  
M. S. Eliseev ◽  
M. V. Shestakova ◽  
E. L. Nasonov
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Type 2 Diabetes Mellitus ◽  
New Drugs ◽  
Positive Effects ◽  
The Metabolic Syndrome ◽  
Sodium Glucose Cotransporter ◽  
The Russian Federation

Currently, only two drugs for reducing uric acid (UA), allopurinol and febuxostat, are registered in the Russian Federation, but their use does not allow to achieve the target level of UA in all cases. According to the results of numerous randomized trials, hyperuricemia and gout are associated with the corresponding components of the metabolic syndrome, including diabetes mellitus. The influence of factors is due to the need to search for new drugs that have a complex effect on several components of metabolic syndrome at once. Potentially attractive in this regard is a new group of drugs for the treatment of type 2 diabetes mellitus inhibitors of the sodium-glucose cotransporter of type 2, which, in addition to the main hypoglycemic actions, showed positive effects on the cardiovascular system, kidneys, as well as lowering UA.

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