scholarly journals Copper/reduced graphene oxide film modified electrode for non-enzymatic glucose sensing application

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sopit Phetsang ◽  
Pinit Kidkhunthod ◽  
Narong Chanlek ◽  
Jaroon Jakmunee ◽  
Pitchaya Mungkornasawakul ◽  
...  

AbstractNumerous studies suggest that modification with functional nanomaterials can enhance the electrode electrocatalytic activity, sensitivity, and selectivity of the electrochemical sensors. Here, a highly sensitive and cost-effective disposable non-enzymatic glucose sensor based on copper(II)/reduced graphene oxide modified screen-printed carbon electrode is demonstrated. Facile fabrication of the developed sensing electrodes is carried out by the adsorption of copper(II) onto graphene oxide modified electrode, then following the electrochemical reduction. The proposed sensor illustrates good electrocatalytic activity toward glucose oxidation with a wide linear detection range from 0.10 mM to 12.5 mM, low detection limit of 65 µM, and high sensitivity of 172 μA mM–1 cm–2 along with satisfactory anti-interference ability, reproducibility, stability, and the acceptable recoveries for the detection of glucose in a human serum sample (95.6–106.4%). The copper(II)/reduced graphene oxide based sensor with the superior performances is a great potential for the quantitation of glucose in real samples.

2021 ◽  
Author(s):  
Sopit Phetsang ◽  
Pinit Kidkhunthod ◽  
Narong Chanlek ◽  
Jaroon Jakmunee ◽  
Pitchaya Mungkornasawakul ◽  
...  

Abstract Numerous studies suggest that modification with functional nanomaterials can enhance the electrode electrocatalytic activity, sensitivity, and selectivity of the electrochemical sensors. Here, a highly sensitive and cost-effective disposable non-enzymatic glucose sensor based on copper(II)/reduced graphene oxide modified screen-printed carbon electrode is demonstrated. Facile fabrication of the developed sensing electrodes is carried out by the adsorption of copper(II) onto graphene oxide modified electrode, then following the electrochemical reduction. The proposed sensor illustrates good electrocatalytic activity toward glucose oxidation with a wide linear detection range from 0.10 mM to 12.5 mM, low detection limit of 65 µM, and high sensitivity of 172 µA mM− 1 cm− 2 along with satisfactory anti-interference ability, reproducibility, stability, and the acceptable recoveries for the detection of glucose in a human serum sample (95.6–106.4%). The copper(II)/reduced graphene oxide based sensor with the superior performances is a great potential for the quantitation of glucose in real samples.


RSC Advances ◽  
2018 ◽  
Vol 8 (57) ◽  
pp. 32565-32573 ◽  
Author(s):  
Shaojun Yang ◽  
Daliang Liu ◽  
Qing Bo Meng ◽  
Shuyao Wu ◽  
Xi-Ming Song

A novel electrochemical glucose sensor based on methylene blue-reduced graphene oxide nanocomposite was constructed, and the sensor exhibited good glucose oxidase-mimetic electrocatalytic activity towards glucose and practical applicability.


2018 ◽  
Vol 10 (3) ◽  
pp. 381-388 ◽  
Author(s):  
Xiaoyi Yan ◽  
Yue Gu ◽  
Cong Li ◽  
Bo Zheng ◽  
Yaru Li ◽  
...  

A CuS nanoflakes–reduced graphene oxide nanocomposite was synthesized successfully for non-enzymatic glucose sensing.


2018 ◽  
Vol 6 (29) ◽  
pp. 14367-14379 ◽  
Author(s):  
A. T. Ezhil Vilian ◽  
Bose Dinesh ◽  
Muruganantham Rethinasabapathy ◽  
Seung-Kyu Hwang ◽  
Chang-Soo Jin ◽  
...  

Reduced graphene oxide (RGO) incorporated onto metal–organic framework (MOF)-derived Co3O4 hexagons is prepared via a hydrothermal route for supercapacitor and glucose sensor applications.


2019 ◽  
Vol 9 (4) ◽  
pp. 622 ◽  
Author(s):  
Cheng-You Liu ◽  
Yi-Chieh Chou ◽  
Jui-Hsuan Tsai ◽  
Tzu-Ming Huang ◽  
Jian-Zhang Chen ◽  
...  

Tyrosinase, chitosan, and reduced graphene oxide (rGO) are sequentially used to modify a screen-printed carbon electrode (SPCE) for the detection of dopamine (DA), without interference from uric acid (UA) or ascorbic acid (AA). The use of tyrosinase significantly improves the detection’s specificity. Cyclic voltammetry (CV) measurements demonstrate the high sensitivity and selectivity of the proposed electrochemical sensors, with detection limits of 22 nM and broad linear ranges of 0.4–8 μM and 40–500 μM. The fabricated tyrosinase/chitosan/rGO/SPCE electrodes achieve satisfactory results when applied to human urine samples, thereby demonstrating their feasibility for analyzing DA in physiological samples.


2015 ◽  
Vol 3 (2) ◽  
pp. 608-616 ◽  
Author(s):  
Li Wang ◽  
Xingping Lu ◽  
Cunjin Wen ◽  
Yingzhen Xie ◽  
Longfei Miao ◽  
...  

A novel nonenzymatic glucose sensor was constructed based on rGO supported Pt–NiO nanoplate arrays through a simple one-step synthesis.


Nanomaterials ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 115 ◽  
Author(s):  
Quanguo He ◽  
Yiyong Wu ◽  
Yaling Tian ◽  
Guangli Li ◽  
Jun Liu ◽  
...  

A new electrochemical sensor for nanomolar rutin detection based on amine-functionalized Fe3O4 nanoparticles and electrochemically reduced graphene oxide nanocomposite modified glassy carbon electrode (NH2-Fe3O4 NPs-ErGO/GCE) was fabricated through a simple method, and the X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscope (SEM), transmission electron microscope (TEM), vibrating sample magnetometer (VSM) and electrochemical technique were used to characterize the modified electrode. The electrochemical behavior of rutin on the Fe3O4 NPs-ErGO/GCE was studied in detail. The electrochemical response of rutin at this modified electrode was remarkably higher than that of the bare GCE or other modified GCE (GO/GCE, Fe3O4 NPs-GO/GCE, and ErGO/GCE). Under the optimum determination conditions, Fe3O4 NPs-ErGO/GCE provided rutin with a broader detection range of 6.0 nM–0.1 µM; 0.1–8.0 µM and 8.0–80 µM, a minimum detectable concentration of 4.0 nM was obtained after 210 s accumulation. This novel method was applied in determination of rutin in pharmaceutical tablets and urine samples with satisfactory results.


2021 ◽  
Vol 20 (02) ◽  
pp. 2150020
Author(s):  
Vijay Kumar Anand ◽  
Kapil Bhatt ◽  
Sandeep Kumar ◽  
B. Archana ◽  
Sandeep Sharma ◽  
...  

In this paper, we report the preparation and characterization of a sensitive and reusable nonenzymatic glucose (NEG) sensor based on copper nanowires (CuNWs)/polyaniline (PANI)/reduced graphene oxide (rGO) nanocomposite ink. The CuNWs/PANI/rGO nanocomposite ink was prepared by solvothermal mixing of CuNWs, PANI, rGO and binders. The X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), Fourier Transform Infra-Red (FT-IR) spectroscopy techniques were used to assess the structural and morphological parameters of prepared nanocomposite ink. The cyclic voltammetry (CV) technique was used to estimate the electrochemical behavior of prepared NEG sensor. The structural, morphological and spectroscopy results confirmed the change in morphological and oxidation state of CuNWs to CuO nanostructures as a constituent of nanocomposite ink. The CuO nanostructures supported on PANI/rGO demonstrated good electrochemical stability and great electrocatalytic activity toward glucose oxidation. At a glucose oxidation potential of 0.64V, the prepared NEG sensor exhibited great electrocatalytic ability by offering a high sensitivity of 843.06[Formula: see text]AmM[Formula: see text]cm[Formula: see text] in the linear glucose range 0–4mM with a lower detection limit of 1.6mM. In addition to these outstanding performance characteristics, CuNWs/PANI/rGO nanocomposite ink-based NEG sensor has the advantages of ease of fabrication, low cost and reusability.


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