scholarly journals Author Correction: Human volunteer study of the decontamination of chemically contaminated hair and the consequences for systemic exposure

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Samuel Collins ◽  
Thomas James ◽  
Felicity Southworth ◽  
Louise Davidson ◽  
Natalie Williams ◽  
...  
Keyword(s):  
Systemic Exposure ◽  
Human Volunteer ◽  
Volunteer Study

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

scholarly journals Human volunteer study of the decontamination of chemically contaminated hair and the consequences for systemic exposure

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Samuel Collins ◽  
Thomas James ◽  
Felicity Southworth ◽  
Louise Davidson ◽  
Natalie Williams ◽  
...  
Keyword(s):  
United Kingdom ◽  
Methyl Salicylate ◽  
Systemic Exposure ◽  
Mass Casualty ◽  
Human Studies ◽  
Human Volunteer ◽  
Toxic Chemicals ◽  
Systemic Bioavailability ◽  
Volunteer Study ◽  
Careful Management

AbstractThe decontamination of exposed persons is a priority following the release of toxic chemicals. Efficacious decontamination reduces the risk of harm to those directly affected and prevents the uncontrolled spread of contamination. Human studies examining the effectiveness of emergency decontamination procedures have primarily focused on decontaminating skin, with few examining the decontamination of hair and scalp. We report the outcome of two studies designed to evaluate the efficacy of current United Kingdom (UK) improvised, interim and specialist mass casualty decontamination protocols when conducted in sequence. Decontamination efficacy was evaluated using two chemical simulants, methyl salicylate (MeS) and benzyl salicylate (BeS) applied to and recovered from the hair of volunteers. Twenty-four-hour urinary MeS and BeS were measured as a surrogate for systemic bioavailability. Current UK decontamination methods performed in sequence were partially effective at removing MeS and BeS from hair and underlying scalp. BeS and MeS levels in urine indicated that decontamination had no significant effect on systemic exposure raising important considerations with respect to the speed of decontamination. The decontamination of hair may therefore be challenging for first responders, requiring careful management of exposed persons following decontamination. Further work to extend these studies is required with a broader range of chemical simulants, a larger group of volunteers and at different intervention times.

Human volunteer study on the inhalational and dermal absorption of N-methyl-2-pyrrolidone (NMP) from the vapour phase

2007 ◽  
Vol 82 (1) ◽  
pp. 13-20 ◽  
Author(s):  
Michael Bader ◽  
Renate Wrbitzky ◽  
Meinolf Blaszkewicz ◽  
Michael Schäper ◽  
Christoph van Thriel
Keyword(s):  
Vapour Phase ◽  
Dermal Absorption ◽  
Human Volunteer ◽  
Volunteer Study

scholarly journals A Human Volunteer Study to Determine the Prebiotic Effects of Lactulose Powder on Human Colonic Microbiota

2002 ◽  
Vol 14 (3) ◽  
pp. 165-173 ◽  
Author(s):  
Kieran M. Tuohy ◽  
Cherie J. Ziemer ◽  
Annett Klinder ◽  
Yvonne Knöbel ◽  
Beatrice L. Pool-Zobel ◽  
...  
Keyword(s):  
Human Volunteer ◽  
Colonic Microbiota ◽  
Volunteer Study

Impact of coffee consumption on the gut microbiota: A human volunteer study

2009 ◽  
Vol 130 (2) ◽  
pp. 117-121 ◽  
Author(s):  
Muriel Jaquet ◽  
Isabelle Rochat ◽  
Julie Moulin ◽  
Christophe Cavin ◽  
Rodrigo Bibiloni
Keyword(s):  
Gut Microbiota ◽  
Coffee Consumption ◽  
Human Volunteer ◽  
Volunteer Study

Human volunteer study with PGME: eye irritation during vapour exposure

2003 ◽  
Vol 140-141 ◽  
pp. 249-259 ◽  
Author(s):  
H.H Emmen ◽  
H Muijser ◽  
J.H.E Arts ◽  
M.K Prinsen
Keyword(s):  
Human Volunteer ◽  
Eye Irritation ◽  
Volunteer Study
Sign in / Sign up

Export Citation Format

Share Document