scholarly journals Effects of palm oil and dietary cholesterol on plasma lipoproteins: results from a dietary crossover trial in free-living subjects

2001 ◽  
Vol 55 (9) ◽  
pp. 748-754 ◽  
Author(s):  
LE Bautista ◽  
OF Herrán ◽  
C Serrano
Keyword(s):  
Palm Oil ◽  
Crossover Trial ◽  
Dietary Cholesterol ◽  
Plasma Lipoproteins ◽  
Free Living

Dietary Cholesterol and Plasma Lipoproteins

1983 ◽  
pp. 238-241
Author(s):  
J. Nestel ◽  
T. Billington
Keyword(s):  
Dietary Cholesterol ◽  
Plasma Lipoproteins

2 month evening and night closed-loop glucose control in patients with type 1 diabetes under free-living conditions: a randomised crossover trial

2015 ◽  
Vol 3 (12) ◽  
pp. 939-947 ◽  
Author(s):  
Jort Kropff ◽  
Simone Del Favero ◽  
Jerome Place ◽  
Chiara Toffanin ◽  
Roberto Visentin ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Glucose Control ◽  
Closed Loop ◽  
Crossover Trial ◽  
Living Conditions ◽  
Free Living ◽  
Free Living Conditions

scholarly journals Home Use of Day-and-Night Hybrid Closed-Loop Insulin Delivery in Suboptimally Controlled Adolescents With Type 1 Diabetes: A 3-Week, Free-Living, Randomized Crossover Trial

Diabetes Care ◽  
2016 ◽  
Vol 39 (11) ◽  
pp. 2019-2025 ◽  
Author(s):  
Martin Tauschmann ◽  
Janet M. Allen ◽  
Malgorzata E. Wilinska ◽  
Hood Thabit ◽  
Carlo L. Acerini ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Closed Loop ◽  
Crossover Trial ◽  
Insulin Delivery ◽  
Free Living ◽  
Randomized Crossover Trial

scholarly journals Effects of dietary cholesterol on plasma lipoproteins and their subclasses in IDDM patients

Diabetologia ◽  
1998 ◽  
Vol 41 (2) ◽  
pp. 193-200 ◽  
Author(s):  
G. Romano ◽  
M. K. Tilly-Kiesi ◽  
L. Patti ◽  
M.-R. Taskinen ◽  
D. Pacioni ◽  
...  
Keyword(s):  
Dietary Cholesterol ◽  
Plasma Lipoproteins

scholarly journals Cholesterolaemic Effects of the Saturated Fatty Acids of Palm Oil

1994 ◽  
Vol 15 (2) ◽  
pp. 1-7 ◽  
Author(s):  
Pramod Khosla ◽  
K. C. Hayes
Keyword(s):  
Fatty Acids ◽  
Palmitic Acid ◽  
Palm Oil ◽  
Cholesterol Metabolism ◽  
Plasma Cholesterol ◽  
Saturated Fatty Acids ◽  
Dietary Cholesterol ◽  
Dietary Fatty Acids ◽  
Potential Health ◽  
Minimal Impact

Dietary saturated fats are implicated as a major risk factor in hypercholesterolaemia and cardiovascular disease. Palm oil is a major source of the world's supply of oils and fats, but because of its relatively high content of saturated fatty acids (principally palmitic acid), its consumption has come under intense scrutiny over the last decade owing to potential health implications. Based on studies carried out more than thirty years ago, the hypothesis was developed that lauric, myristic, and palmitic acid were the three principal cholesterol-raising saturated fatty acids. Since palmitic acid is the most abundant fatty acid in the diet, the cholesterol-raising effect of all saturated fatty acids was accordingly assigned to it. However, recent studies from both humans and experimental animals suggest that not all saturated fatty acids are cholesterol-raising. When all dietary fatty acids are equalized, with the exception of the two being tested, palmitic acid appears to have no impact on the plasma cholesterol in normocholesterolaemic subjects when dietary cholesterol intake is below a certain critical level (400 mg per day). Only when cholesterol consumption exceeds this level, or when hypercholesterolaemic subjects are studied, does palmitic acid appear to increase the plasma cholesterol. These differential effects of palmitic acid on plasma cholesterol are thought to reflect differences in LDL-receptor status. Collectively these data imply that, for most of the world's population, palm oil would be an inexpensive and readily metabolized source of dietary energy with minimal impact on cholesterol metabolism.

scholarly journals Daily Consumption of Virgin Coconut Oil Increases High-Density Lipoprotein Cholesterol Levels in Healthy Volunteers: A Randomized Crossover Trial

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Surarong Chinwong ◽  
Dujrudee Chinwong ◽  
Ampica Mangklabruks
Keyword(s):  
High Density Lipoprotein ◽  
High Density Lipoprotein Cholesterol ◽  
Crossover Trial ◽  
Density Lipoprotein ◽  
Coconut Oil ◽  
High Density ◽  
Lipoprotein Cholesterol ◽  
Plasma Lipoproteins ◽  
Daily Consumption

This open-label, randomized, controlled, crossover trial assessed the effect of daily virgin coconut oil (VCO) consumption on plasma lipoproteins levels and adverse events. The study population was 35 healthy Thai volunteers, aged 18–25. At entry, participants were randomly allocated to receive either (i) 15 mL VCO or (ii) 15 mL 2% carboxymethylcellulose (CMC) solution (as control), twice daily, for 8 weeks. After 8 weeks, participants had an 8-week washout period and then crossed over to take the alternative regimen for 8 weeks. Plasma lipoproteins levels were measured in participants at baseline, week-8, week-16, and week-24 follow-up visits.Results. Of 32 volunteers with complete follow-up (16 males and 16 females), daily VCO intake significantly increased high-density lipoprotein cholesterol by 5.72 mg/dL (p=0.001) compared to the control regimen. However, there was no difference in the change in total cholesterol, low-density lipoprotein cholesterol, and triglyceride levels between the two regimens. Mild diarrhea was reported by some volunteers when taking VCO, but no serious adverse events were reported.Conclusion. Daily consumption of 30 mL VCO in young healthy adults significantly increased high-density lipoprotein cholesterol. No major safety issues of taking VCO daily for 8 weeks were reported.

scholarly journals Plasma activities of lecithin:cholesterol acyltransferase, lipid transfer proteins and post-heparin lipases in inbred strains of rabbits hypo- or hyper-responsive to dietary cholesterol

1993 ◽  
Vol 293 (3) ◽  
pp. 729-734 ◽  
Author(s):  
G W Meijer ◽  
P N M Demacker ◽  
A Van Tol ◽  
J E M Groener ◽  
J G P Van der Palen ◽  
...  
Keyword(s):  
Plasma Cholesterol ◽  
Strain Difference ◽  
Dietary Cholesterol ◽  
Inbred Strains ◽  
Plasma Lipoproteins ◽  
High Cholesterol Diet ◽  
Lecithin:Cholesterol Acyltransferase ◽  
Triacylglycerol Lipase ◽  
Transfer Protein ◽  
Pltp Activity

Plasma lipoproteins, plasma activities of lecithin:cholesterol acyltransferase (LCAT), phospholipid transfer protein (PLTP), cholesteryl ester transfer protein (CETP) and post-heparin lipases were measured before and after cholesterol challenge in two inbred strains of rabbits with either a high (hyper-responders) or a low (hyporesponders) response of plasma cholesterol to dietary cholesterol. The purpose of this study was to provide clues about the mechanisms underlying the effect of dietary cholesterol on lipoprotein levels and composition, and particularly those underlying the strain difference of this effect. Cholesterol feeding (0.15 g of cholesterol/100 g of diet) caused increased plasma total cholesterol concentrations and an increased ratio of cholesteryl esters:triacylglycerol in all lipoprotein particles in both strains; these effects were significantly greater in hyper- than hypo-responsive rabbits. Feeding on the high-cholesterol diet lowered plasma triacylglycerols in hyper-responders, but caused increased plasma triacylglycerol levels in hyporesponders. This was accompanied by significantly greater increases in the activities of hepatic triacylglycerol lipase and lipoprotein lipase in hyper- than in hypo-responders. Both strains showed a dietary-cholesterol-induced rise in plasma CETP as well as in PLTP activity. The increase in PLTP activity was greater in the hyper-responders, but that of CETP was less. There was no effect of dietary cholesterol on LCAT activity. It is hypothesized that the lipases are involved in the removal of cholesterol-rich lipoproteins.

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