scholarly journals Metastatic squamous cell carcinoma cells that overexpress c-Met exhibit enhanced angiogenesis factor expression, scattering and metastasis in response to hepatocyte growth factor

Oncogene ◽  
2004 ◽  
Vol 23 (37) ◽  
pp. 6199-6208 ◽  
Author(s):  
Gang Dong ◽  
Tin Lap Lee ◽  
Ning T Yeh ◽  
Joel Geoghegan ◽  
Carter Van Waes ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Growth Factor ◽  
Hepatocyte Growth Factor ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Carcinoma Cells ◽  
Angiogenesis Factor ◽  
Metastatic Squamous Cell Carcinoma ◽  
Factor Expression ◽  
Hepatocyte Growth

Expression of hepatocyte growth factor and c-Met in hypopharyngeal squamous cell carcinoma

2006 ◽  
Vol 126 (1) ◽  
pp. 88-94 ◽  
Author(s):  
Chul-Ho Kim ◽  
Sung-Kyun Moon ◽  
Joon-Ho Bae ◽  
Jae Ho Lee ◽  
Jae Ho Han ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Growth Factor ◽  
Hepatocyte Growth Factor ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Hypopharyngeal Squamous Cell Carcinoma ◽  
Hepatocyte Growth

Hepatocyte Growth Factor/Scatter Factor Stimulates Mitogenesis and Migration of a Head and Neck Squamous Cell Carcinoma Cell Line

2002 ◽  
Vol 127 (4) ◽  
pp. 271-278 ◽  
Author(s):  
Jeffery Fleigel ◽  
Jack Sedwick ◽  
Lori J. Kornberg
Keyword(s):  
Squamous Cell Carcinoma ◽  
Growth Factor ◽  
Hepatocyte Growth Factor ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Cell Line ◽  
Squamous Cell ◽  
Cultured Cells ◽  
Scatter Factor ◽  
Hepatocyte Growth

OBJECTIVE: We sought to assess the effect of extracellular matrix and hepatocyte growth factor/scatter factor (HGF/SF) on the growth and motility of cultured squamous cell carcinoma of the head and neck (SCCHN) cells. METHODS: Cultured cells were incubated in the presence of HGF/SF. The effect of HFG/SF on cell growth, motility, and phosphorylation of the signaling proteins FAK and Erk was determined. RESULTS: HGF/SF is both mitogenic and motogenic to the human SCCHN cell line FaDu. Incubation of FaDu cells in the presence of HGF/SF led to a rapid increase in phosphorylation of both FAK and the growth-promoting kinase Erk. HGF/SF-induced phosphorylation of FAK and Erk was observed in both detached and attached SCCHN cells. However, phosphorylation was much greater in attached cells. CONCLUSIONS AND SIGNIFICANCE: The mitogenic and motogenic activities of HGF/SF may contribute to the pathogenesis of SCCHN in vivo.

Cytoplasmic hepatocyte growth factor immunoreactivity predicting lymph node metastasis in esophageal squamous cell carcinoma

Esophagus ◽  
2014 ◽  
Vol 11 (4) ◽  
pp. 223-230 ◽  
Author(s):  
Yohei Ozawa ◽  
Yasuhiro Nakamura ◽  
Fumiyoshi Fujishima ◽  
Saulo J. A. Felizola ◽  
Kenichiro Takeda ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Growth Factor ◽  
Lymph Node Metastasis ◽  
Esophageal Squamous Cell Carcinoma ◽  
Hepatocyte Growth Factor ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Node Metastasis ◽  
Hepatocyte Growth

scholarly journals Regulation of microRNA expression by hepatocyte growth factor in human head and neck squamous cell carcinoma

2011 ◽  
Vol 102 (12) ◽  
pp. 2164-2171 ◽  
Author(s):  
Dai Susuki ◽  
Sotai Kimura ◽  
Seiji Naganuma ◽  
Katsuki Tsuchiyama ◽  
Toshiaki Tanaka ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Growth Factor ◽  
Hepatocyte Growth Factor ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Human Head ◽  
Microrna Expression ◽  
Neck Squamous Cell Carcinoma ◽  
Hepatocyte Growth
Sign in / Sign up

Export Citation Format

Share Document