scholarly journals Homeostatic chemokines increase survival of B-chronic lymphocytic leukemia cells through inactivation of transcription factor FOXO3a

Oncogene ◽  
2007 ◽  
Vol 26 (50) ◽  
pp. 7081-7091 ◽  
Author(s):  
M Ticchioni ◽  
M Essafi ◽  
P Y Jeandel ◽  
F Davi ◽  
J P Cassuto ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Chronic Lymphocytic Leukemia ◽  
Lymphocytic Leukemia ◽  
Leukemia Cells

scholarly journals Autologous T cells expressing the oncogenic transcription factor KLF6-SV1 prevent apoptosis of chronic lymphocytic leukemia cells

PLoS ONE ◽  
2018 ◽  
Vol 13 (2) ◽  
pp. e0192839 ◽  
Author(s):  
Parviz Kokhaei ◽  
Mohammad Hojjat-Farsangi ◽  
Fariba Mozaffari ◽  
Ali Moshfegh ◽  
Fatemeh Pak ◽  
...  
Keyword(s):  
T Cells ◽  
Transcription Factor ◽  
Chronic Lymphocytic Leukemia ◽  
Lymphocytic Leukemia ◽  
Leukemia Cells ◽  
Oncogenic Transcription Factor

scholarly journals Targeting DNA Repair in Chronic Lymphocytic Leukemia Cells with a Novel Acyclic Nucleotide Analogue, GS-9219

2009 ◽  
Vol 15 (11) ◽  
pp. 3760-3769 ◽  
Author(s):  
Cheng-Yu Tsai ◽  
Adrian S. Ray ◽  
Daniel B. Tumas ◽  
Michael J. Keating ◽  
Hans Reiser ◽  
...  
Keyword(s):  
Dna Repair ◽  
Chronic Lymphocytic Leukemia ◽  
Lymphocytic Leukemia ◽  
Leukemia Cells ◽  
Nucleotide Analogue

scholarly journals Induction of histone H1.2 cytosolic release in chronic lymphocytic leukemia cells after genotoxic and non-genotoxic treatment

Haematologica ◽  
2008 ◽  
Vol 93 (1) ◽  
pp. 75-82 ◽  
Author(s):  
E. Gine ◽  
M. Crespo ◽  
A. Muntanola ◽  
E. Calpe ◽  
M. J. Baptista ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Lymphocytic Leukemia ◽  
Leukemia Cells

A novel monoclonal antibody recognizing human thymocytes and B-cell chronic lymphocytic leukemia cells

1994 ◽  
Vol 39 (2) ◽  
pp. 137-146 ◽  
Author(s):  
P. Tassone ◽  
P. Bonelli ◽  
F. Tuccillo ◽  
H.M. Bond ◽  
M.C. Turco ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Chronic Lymphocytic Leukemia ◽  
B Cell ◽  
Lymphocytic Leukemia ◽  
Leukemia Cells ◽  
Cell Chronic Lymphocytic Leukemia

scholarly journals Chronic lymphocytic leukemia cells induce defective LFA-1–directed T-cell motility by altering Rho GTPase signaling that is reversible with lenalidomide

Blood ◽  
2013 ◽  
Vol 121 (14) ◽  
pp. 2704-2714 ◽  
Author(s):  
Alan G. Ramsay ◽  
Rachel Evans ◽  
Shahryar Kiaii ◽  
Lena Svensson ◽  
Nancy Hogg ◽  
...  
Keyword(s):  
T Cell ◽  
Chronic Lymphocytic Leukemia ◽  
Cell Motility ◽  
Rho Gtpase ◽  
Lymphocytic Leukemia ◽  
Leukemia Cells ◽  
Key Points ◽  
Gtpase Activation ◽  
Activation Signaling

Key Points CLL cells induce defects in T-cell LFA-1–mediated migration by altering Rho GTPase activation signaling, downregulating RhoA and Rac1, and upregulating Cdc42. Lenalidomide repairs these T-cell defects by restoring normal Rho GTPase activation signaling.

The induction of p53 and WAF1/CIP1 in chronic lymphocytic leukemia cells treated with 2-chlorodeoxyadenosine

1996 ◽  
Vol 74 (3) ◽  
pp. 143-147 ◽  
Author(s):  
R. B. Gartenhaus ◽  
P. Wang ◽  
M. Hoffman ◽  
D. Janson ◽  
K. R. Rai
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Lymphocytic Leukemia ◽  
Leukemia Cells
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