Hospitalization risk factors for children’s lower respiratory tract infection: A population-based, cross-sectional study in Mongolia

Background: Prescription audit is an important tool to analyse rational use of drug at different health sectors. The aim of the study was to evaluate the prescribing pattern using World Health Organization prescribing indicators for lower respiratory tract infection in children below five years of age.Methods: A cross-sectional study was conducted in the outpatient department of Paediatrics at Central Referral Hospital, Gangtok, Sikkim, India for a period of 18 months. Study involved children between 1-5 years of age with fever/cough with or without respiratory distress. The data were collected from the out patient department prescription slips as well as interviewing the parents/guardians after finishing the physician consultation. The data were processed using statistical software SPSS 20.Results: The study was conducted with 57 prescriptions comprising 210 drugs from both male (54.38%) and female (45.61%) patients. The average number of drugs per prescription was found to be 3.68. negligible (0.013%) prescription containing generic name of drug was found, 96.66% of medicines were prescribed from National Essential List of Medicine (NELM). No prescriptions were found to have injectables, 8.57% of the prescriptions were found to contain fixed dose combination. Amongst the drug categories, salbutamol accounted for 23.33% in total prescription followed by paracetamol (22.85%) and amoxicillin (7.14%). While accounting for the formulations used, the maximum prescriptions were containing syrup followed by nebulization.Conclusions: The use of generic names was minimal, only few of the prescriptions had vitamins and tonics with no use of injectable preparations. Maximum numbers of drugs were prescribed from NELM.

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Bacteriology of Sputum Samples: A Descriptive Cross-sectional Study in a Tertiary Care Hospital

Journal of Nepal Medical Association ◽

10.31729/jnma.4807 ◽

2020 ◽

Vol 58 (221) ◽

Author(s):

Bijendra Raj Raghubanshi ◽

Bal Man Singh Karki

Keyword(s):

Tract Infection ◽

Respiratory Tract ◽

Respiratory Tract Infection ◽

Lower Respiratory Tract Infection ◽

Lower Respiratory Tract ◽

Sputum Sample ◽

Cross Sectional Study ◽

Care Hospital ◽

Sectional Study ◽

Cross Sectional

Introduction: Lower respiratory tract infection is a common infection and accounts for a greaterburden of disease worldwide. It is a great challenge to the clinician and still more, with increasingantimicrobial resistance. Its empirical treatment may vary according to the type of causativeorganisms. The objective of this study is to identify the pathogenic microorganisms and theirantimicrobial susceptibility pattern from sputum sample. Methods: This descriptive cross-sectional study was conducted in KIST Medical College andTeaching Hospital from February 2015 to January 2016. Ethical approval was taken from institutionalreview committee prior to the study with reference no. 0051/2014/15. Data on culture and sensitivityof isolates from sputum samples were collected from the records of the hospital. Sample collection,processing, identification of microorganisms and antimicrobial susceptibility tests were performedaccording to the Clinical and Laboratory Standards Institute guidelines. All the data were tabulatedin an Excel sheet and analyzed using SPSS version 20. Results: Out of 2318 samples, 694 (29.93%) sputum samples at 95% confidence interval (737.21-650.79) were reported as culture positive. Klebsiella was the most common isolate followedby Pseudomonas, Escherichia coli, Acinetobacter, Staphylococcus aureus, Candida albicans,Streptococcus pneumoniae, Streptococcus pyogenes, and others. Imipenem and vancomycin showedthe most sensitivity towards gram-negative and gram-positive bacteria respectively. Conclusions: Proper diagnosis, identification of causative agents and their antimicrobial susceptibilitypattern are important steps to limit the irrational use of antimicrobials. Prescribing antimicrobialsempirically in the case of suspected lower respiratory tract infection is difficult.

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A cross sectional study on risk factors associated with acute lower respiratory tract infection among children aged 6 to 60 months

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20204415 ◽

2020 ◽

Vol 7 (11) ◽

pp. 2219

Author(s):

Tabrez Altaf Noorani ◽

Jaini S. Kothari ◽

Bhavesh Kanabar

Keyword(s):

Risk Factors ◽

Tract Infection ◽

Respiratory Tract ◽

Respiratory Tract Infection ◽

Lower Respiratory Tract Infection ◽

Lower Respiratory Tract ◽

Cross Sectional Study ◽

Age Group ◽

Cross Sectional ◽

Socio Demographic Factors

Background: Acute lower respiratory tract infection (ALRI) is leading cause of hospitalization and mortality among children under 5 years age in developing societies. Risk factors such as socioeconomic status, overcrowding, parental education, passive smoking, exposure to biomass fuels, kerosene lamps etc should also be considered in possible etiology of ALRI. Knowledge of risk factors would help prevention through proper health education efforts and other interventional community development initiatives. The objective of the study was to study various socio-demographic and nutritional risk factors associated with acute lower respiratory tract infection among 6 to 60 months aged childrenMethods: This cross-sectional study was conducted in a tertiary care institute Gujarat state of India. All the children in the age group of 6 months to 60 months admitted in paediatrics ward with ALRI were included in study. Data collection was done using a pretested questionnaire including socio-demographic factors. Data was analyzed using Statistical package for social sciences (SPSS) and excel and p<0.05 was considered as statistically significant.Results: Higher percentage (32%) of malnutrition was observed in age group of 13 months to 36 months (p<0.05). Lack of maternal education is significantly associated with malnutrition in patients of acute lower respiratory tract infection (LRTI) (p<0.05). Passive smoking was found among 38.1% of ALRI patients in urban area while it was among 25.6% of patients in rural patients (p<0.05). Difference in exposure to biomass fuel among rural and urban patients is statistically significant (p<0.05). Giving pre-lacteal feeding (63.9%), incomplete immunization (56.8%), no birth spacing (50.2%), no predominant breast feeding (47.7%) are some of the leading causes of acute LRTI.Conclusion: Socio-demographic factors and malnutrition impact ALRI among 6 to 60 months age group of children according to place of residence.

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