The Role of PIK3CA Mutations among Lung Adenocarcinoma Patients with Primary and Acquired Resistance to EGFR Tyrosine Kinase Inhibition

Scientific Reports ◽

10.1038/srep35249 ◽

2016 ◽

Vol 6 (1) ◽

Author(s):

Shang-Gin Wu ◽

Yih-Leong Chang ◽

Chong-Jen Yu ◽

Pan-Chyr Yang ◽

Jin-Yuan Shih

Keyword(s):

Tyrosine Kinase ◽

Lung Adenocarcinoma ◽

Acquired Resistance ◽

Kinase Inhibition ◽

Pik3ca Mutations ◽

Tyrosine Kinase Inhibition ◽

Egfr Tyrosine Kinase

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Blockade of AXL activation overcomes acquired resistance to EGFR tyrosine kinase inhibition in non-small cell lung cancer

Translational Cancer Research ◽

10.21037/tcr.2019.09.61 ◽

2019 ◽

Vol 8 (6) ◽

pp. 2425-2438 ◽

Author(s):

Feng Wang ◽

Xuewen Liu ◽

Boris A. Bartholdy ◽

Haiying Cheng ◽

Balazs Halmos

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Acquired Resistance ◽

Small Cell Lung ◽

Kinase Inhibition ◽

Tyrosine Kinase Inhibition ◽

Egfr Tyrosine Kinase

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P1.01-60 Prognostic Impact of PD-L1 Expression on EGFR Tyrosine Kinase Inhibition in Lung Adenocarcinoma

Journal of Thoracic Oncology ◽

10.1016/j.jtho.2019.08.775 ◽

2019 ◽

Vol 14 (10) ◽

pp. S381-S382

Author(s):

M. Kang ◽

S.H. Kim ◽

S.W. Yoon ◽

K.J. Suh ◽

Y.J. Kim ◽

...

Keyword(s):

Tyrosine Kinase ◽

Lung Adenocarcinoma ◽

Prognostic Impact ◽

Kinase Inhibition ◽

Tyrosine Kinase Inhibition ◽

Egfr Tyrosine Kinase

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Impact of Concurrent PIK3CA Mutations on Response to EGFR Tyrosine Kinase Inhibition in EGFR-Mutant Lung Cancers and on Prognosis in Oncogene-Driven Lung Adenocarcinomas

Journal of Thoracic Oncology ◽

10.1097/jto.0000000000000671 ◽

2015 ◽

Vol 10 (12) ◽

pp. 1713-1719 ◽

Author(s):

Juliana Eng ◽

Kaitlin M. Woo ◽

Camelia S. Sima ◽

Andrew Plodkowski ◽

Matthew D. Hellmann ◽

...

Keyword(s):

Tyrosine Kinase ◽

Kinase Inhibition ◽

Lung Cancers ◽

Pik3ca Mutations ◽

Tyrosine Kinase Inhibition ◽

Egfr Tyrosine Kinase ◽

Egfr Mutant ◽

Lung Adenocarcinomas

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Antiproliferative effects of EGFR tyrosine kinase inhibition and radiation-induced genotoxic injury are attenuated by adhesion to fibronectin

Radiotherapy and Oncology ◽

10.1016/j.radonc.2006.07.028 ◽

2006 ◽

Vol 80 (2) ◽

pp. 178-184 ◽

Author(s):

Iris Eke ◽

Veit Sandfort ◽

Antje Mischkus ◽

Michael Baumann ◽

Nils Cordes

Keyword(s):

Tyrosine Kinase ◽

Kinase Inhibition ◽

Antiproliferative Effects ◽

Tyrosine Kinase Inhibition ◽

Egfr Tyrosine Kinase ◽

Radiation Induced

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HER Kinase Axis Receptor Dimer Partner Switching Occurs in Response to EGFR Tyrosine Kinase Inhibition despite Failure to Block Cellular Proliferation

Cancer Research ◽

10.1158/0008-5472.can-09-3326 ◽

2010 ◽

Vol 70 (5) ◽

pp. 1989-1999 ◽

Author(s):

Anjali Jain ◽

Elicia Penuel ◽

Sheldon Mink ◽

Joanna Schmidt ◽

Amanda Hodge ◽

...

Keyword(s):

Tyrosine Kinase ◽

Cellular Proliferation ◽

Kinase Inhibition ◽

Tyrosine Kinase Inhibition ◽

Egfr Tyrosine Kinase ◽

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Abstract 742: Effect of Hsp90 inhibitor NVP-AUY922 with radiation on lung adenocarcinoma cell lines with acquired resistance to EGFR-tyrosine kinase inhibitors

10.1158/1538-7445.am2015-742 ◽

2015 ◽

Author(s):

Yuho Maki ◽

Shinsuke Hashida ◽

Hiromasa Yamamoto ◽

Kazuhiko Shien ◽

Tomoaki Ohtsuka ◽

...

Keyword(s):

Tyrosine Kinase ◽

Lung Adenocarcinoma ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Acquired Resistance ◽

Hsp90 Inhibitor ◽

Adenocarcinoma Cell ◽

Egfr Tyrosine Kinase ◽

Egfr Tyrosine Kinase Inhibitors

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An activation of LC3A-mediated autophagy contributes tode novoand acquired resistance to EGFR tyrosine kinase inhibitors in lung adenocarcinoma

The Journal of Pathology ◽

10.1002/path.4354 ◽

2014 ◽

pp. n/a-n/a ◽

Author(s):

Kaito Nihira ◽

Yasuhiro Miki ◽

Shinya Iida ◽

Sodai Narumi ◽

Katsuhiko Ono ◽

...

Keyword(s):

Tyrosine Kinase ◽

Lung Adenocarcinoma ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Acquired Resistance ◽

Egfr Tyrosine Kinase ◽

Egfr Tyrosine Kinase Inhibitors

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Acquired Resistance to EGFR Tyrosine Kinase Inhibitors is Associated With Low Efficacy of Radiation Therapy for Brain Metastases From EGFR-mutant Lung Adenocarcinoma

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2012.07.166 ◽

2012 ◽

Vol 84 (3) ◽

pp. S102

Author(s):

H. Hirata ◽

K. Nakamura ◽

N. Kunitake ◽

Y. Shioyama ◽

T. Sasaki ◽

...

Keyword(s):

Radiation Therapy ◽

Brain Metastases ◽

Tyrosine Kinase ◽

Lung Adenocarcinoma ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Acquired Resistance ◽

Egfr Tyrosine Kinase ◽

Egfr Tyrosine Kinase Inhibitors ◽

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The mechanism of acquired resistance to irreversible EGFR tyrosine kinase inhibitor-afatinib in lung adenocarcinoma patients

10.18632/oncotarget.7189 ◽

2016 ◽

Vol 7 (11) ◽

pp. 12404-12413 ◽

Author(s):

Shang-Gin Wu ◽

Yi-Nan Liu ◽

Meng-Feng Tsai ◽

Yih-Leong Chang ◽

Chong-Jen Yu ◽

...

Keyword(s):

Tyrosine Kinase ◽

Lung Adenocarcinoma ◽

Tyrosine Kinase Inhibitor ◽

Kinase Inhibitor ◽

Acquired Resistance ◽

Egfr Tyrosine Kinase Inhibitor ◽

Egfr Tyrosine Kinase

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Unusual Presentation of Lung Adenocarcinoma With Paraneoplastic Stiff Person Syndrome: Role of EGFR Tyrosine Kinase Inhibitors

Journal of Thoracic Oncology ◽

10.1016/j.jtho.2019.03.025 ◽

2019 ◽

Vol 14 (8) ◽

pp. e179-e180

Author(s):

Nawid Sarwari ◽

Yehuda Galili ◽

Ariel Perez ◽

Nicholas Avgeropoulos ◽

Jennifer Tseng

Keyword(s):

Tyrosine Kinase ◽

Lung Adenocarcinoma ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Unusual Presentation ◽

Stiff Person Syndrome ◽

Egfr Tyrosine Kinase ◽

Egfr Tyrosine Kinase Inhibitors

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