Synthesis, molecular modeling and biological activity of methyl and thiomethyl substituted pyrimidines as corticotropin releasing hormone type 1 antagonists

Generation of a Recombinant Herpes Simplex Virus Type 1 Expressing the Rat Corticotropin- Releasing Hormone Precursor: Endoproteolytic Processing, Intracellular Targeting and Biological Activity

Neuroendocrinology ◽

10.1159/000054506 ◽

1999 ◽

Vol 70 (6) ◽

pp. 439-450 ◽

Cited By ~ 6

Author(s):

Peter Tomasec ◽

Christopher M. Preston ◽

Elizabeth A. Linton ◽

Irshad Ahmed ◽

Pedro R. Lowenstein ◽

...

Keyword(s):

Biological Activity ◽

Herpes Simplex Virus ◽

Herpes Simplex ◽

Virus Type ◽

Herpes Simplex Virus Type ◽

Releasing Hormone ◽

Intracellular Targeting ◽

Simplex Virus

ChemInform Abstract: Synthesis and Biological Activity of Fluoro-Substituted Pyrrolo[2,3-d]pyrimidines. The Development of Potential Positron Emission Tomography Imaging Agents for the Corticotropin-Releasing Hormone Type 1 Receptor.

ChemInform ◽

10.1002/chin.200029121 ◽

2010 ◽

Vol 31 (29) ◽

pp. no-no

Author(s):

Ling-Wei Hsin ◽

Elizabeth L. Webster ◽

George P. Chrousos ◽

Philip W. Gold ◽

William C. Eckelman ◽

...

Keyword(s):

Positron Emission Tomography ◽

Biological Activity ◽

Positron Emission Tomography Imaging ◽

Emission Tomography ◽

Imaging Agents ◽

Releasing Hormone ◽

Tomography Imaging ◽

Positron Emission

Synthesis and biological activity of fluoro-substituted pyrrolo[2,3- d ]pyrimidines: The development of potential positron emission tomography imaging agents for the corticotropin-releasing hormone type 1 receptor

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(00)00071-8 ◽

2000 ◽

Vol 10 (8) ◽

pp. 707-710 ◽

Cited By ~ 18

Author(s):

Ling-Wei Hsin ◽

Elizabeth L Webster ◽

George P Chrousos ◽

Philip W Gold ◽

William C Eckelman ◽

...

Keyword(s):

Positron Emission Tomography ◽

Biological Activity ◽

Positron Emission Tomography Imaging ◽

Emission Tomography ◽

Imaging Agents ◽

Releasing Hormone ◽

Tomography Imaging ◽

Positron Emission

Dissecting the role of Corticotropin-releasing hormone receptor type 1 in Alzheimer's Disease

Pharmacopsychiatry ◽

10.1055/s-0031-1292513 ◽

2011 ◽

Vol 44 (06) ◽

Author(s):

K Lerche ◽

M Willem ◽

K Kleinknecht ◽

C Romberg ◽

U Konietzko ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Hormone Receptor ◽

Receptor Type ◽

Corticotropin-releasing hormone receptor type 1-deficiency enhances hippocampal serotonergic neurotransmission: an in vivo microdialysis study in mutant mice

Neuroscience ◽

10.1016/s0306-4522(01)00475-4 ◽

2002 ◽

Vol 109 (2) ◽

pp. 253-266 ◽

Cited By ~ 51

Author(s):

R.G Peñalva ◽

C Flachskamm ◽

S Zimmermann ◽

W Wurst ◽

F Holsboer ◽

...

Keyword(s):

Hormone Receptor ◽

In Vivo Microdialysis ◽

Mutant Mice ◽

Receptor Type ◽

Releasing Hormone ◽

Serotonergic Neurotransmission ◽

Microdialysis Study

Corticotropin-releasing hormone modulates airway vagal preganglionic neurons of Sprague–Dawley rats at multiple synaptic sites via activation of its type 1 receptors: Implications for stress-associated airway vagal excitation

Neuroscience ◽

10.1016/j.neuroscience.2017.04.049 ◽

2017 ◽

Vol 355 ◽

pp. 101-112 ◽

Cited By ~ 2

Author(s):

Yuhong Guo ◽

Xianxia Yan ◽

Xingxin Chen ◽

Ding He ◽

Ming Zeng ◽

...

Keyword(s):

Sprague Dawley ◽

Releasing Hormone ◽

Preganglionic Neurons ◽

Sprague Dawley Rats

Central Deficiency of Corticotropin-Releasing Hormone Receptor Type 1 (CRH-R1) Abolishes Effects of CRH on NREM But Not on REM Sleep in Mice

SLEEP ◽

10.1093/sleep/33.4.427 ◽

2010 ◽

Vol 33 (4) ◽

pp. 427-436 ◽

Cited By ~ 29

Author(s):

Christoph PN Romanowski ◽

Thomas Fenzl ◽

Cornelia Flachskamm ◽

Wolfgang Wurst ◽

Florian Holsboer ◽

...

Keyword(s):

Rem Sleep ◽

Hormone Receptor ◽

Receptor Type ◽

Divergent effects of corticotropin releasing hormone on endothelial cell nitric oxide synthase are associated with different expression of CRH type 1 and 2 receptors

British Journal of Pharmacology ◽

10.1038/sj.bjp.0704322 ◽

2001 ◽

Vol 134 (4) ◽

pp. 837-844 ◽

Cited By ~ 21

Author(s):

Giuseppina Cantarella ◽

Laurence Lempereur ◽

Gabriella Lombardo ◽

Andrea Chiarenza ◽

Carlo Pafumi ◽

...

Keyword(s):

Nitric Oxide ◽

Endothelial Cell ◽

Nitric Oxide Synthase ◽

Releasing Hormone ◽

Oxide Synthase

Letter to editor: Failure to replicate the association of glucocorticoid and type 1 corticotropin-releasing hormone receptors gene variants with risk of depression during pregnancy and post-partum reported by Engineer et al. (2013)

Journal of Psychiatric Research ◽

10.1016/j.jpsychires.2014.04.016 ◽

2014 ◽

Vol 56 ◽

pp. 168-170 ◽

Cited By ~ 11

Author(s):

Evie Stergiakouli ◽

Jonathan A.C. Sterne ◽

George Davey Smith

Keyword(s):

Hormone Receptors ◽

Post Partum ◽

Gene Variants ◽

Visualizing corticotropin-releasing hormone receptor type 1 expression and neuronal connectivities in the mouse using a novel multifunctional allele

The Journal of Comparative Neurology ◽

10.1002/cne.23082 ◽

2012 ◽

Vol 520 (14) ◽

pp. 3150-3180 ◽

Cited By ~ 33

Author(s):

Claudia Kühne ◽

Oliver Puk ◽

Jochen Graw ◽

Martin Hrabě de Angelis ◽

Günther Schütz ◽

...

Keyword(s):

Hormone Receptor ◽

Receptor Type ◽