Antimicrobial surfaces and their potential in reducing the role of the inanimate environment in the incidence of hospital-acquired infections

2009 ◽  
Vol 19 (23) ◽  
pp. 3819 ◽  
Author(s):  
Kristopher Page ◽  
Michael Wilson ◽  
Ivan P. Parkin
Stroke ◽  
2019 ◽  
Vol 50 (Suppl_1) ◽  
Author(s):  
Amelia K Boehme ◽  
Maitreyi Oka ◽  
Bevin Cohen ◽  
Barun Mathema ◽  
Elaine Larson

2017 ◽  
Vol 61 (1) ◽  
pp. 1-10 ◽  
Author(s):  
Henrietta Venter ◽  
Michael L. Henningsen ◽  
Stephanie L. Begg

The crisis of antimicrobial resistance (AMR) is one of the most serious issues facing us today. The scale of the problem is illustrated by the recent commitment of Heads of State at the UN to coordinate efforts to curb the spread of AMR infections. In this review, we explore the biochemistry behind the headlines of a few stories that were recently published in the public media. We focus on examples from three different issues related to AMR: (i) hospital-acquired infections, (ii) the spread of resistance through animals and/or the environment and (iii) the role of antimicrobial soaps and other products containing disinfectants in the dissemination of AMR. Although these stories stem from three very different settings, the underlying message in all of them is the same: there is a direct relationship between the use of antimicrobials and the development of resistance. In addition, one type of antimicrobial could select for cross-resistance to another type and/or for multidrug resistance. Therefore, we argue the case for increased stewardship to not only cover clinical use of antibiotics, but also the use of antimicrobials in agriculture and stewardship of our crucially important biocides such as chlorhexidine.


Atmosphere ◽  
2021 ◽  
Vol 12 (9) ◽  
pp. 1174
Author(s):  
Daniela D’Alessandro ◽  
Massimo Fabiani ◽  
Letizia Appolloni

Intensive care units (ICUs) are special areas in hospitals for patients with severe and life-threatening diseases. ICUs are of several categories, such as neonatal ICUs, cardiac ICUs, neurological ICUs, surgical ICUs, etc. The ICUs’ patients may show a high susceptibility for hospital-acquired infections (HAIs) depending on underlying disease, duration of stay and treatment. ICUs are considered potential reservoirs for (opportunistic) pathogenic microbial strains and the risk of acquiring infection in these hospital environments is higher than in others. Several studies show the role of inanimate surface and equipment contamination in the transmission of pathogens to ICU patients. The aim of this study is to describe the results of 124 sampling campaigns performed during 12 years of microbiological surveillance of five ICUs of different categories, for an overall number of 714 samples (232 from air and 482 from surface), to analyze their trends and to elaborate suggestions to improve ICUs’ environmental quality and patients’ safety.


2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Zihe Yan ◽  
Junjun Yang ◽  
Renjing Hu ◽  
Xichi Hu ◽  
Kong Chen

Acinetobacter baumanniiis a significant cause of severe hospital-acquired infections with a recent rise in multidrug-resistant infections involving traumatic wounds of military personnel. The interleukin-17 (IL-17) pathway is essential for neutrophil recruitment in response to a variety of pathogens, while the control ofA. baumanniiinfection is known to be dependent on neutrophils. This suggests that IL-17 may play an important role inA. baumanniiinfection; however, this has yet to be studied. Here, we summarize the recent advances in understanding the host-pathogen interaction ofA. baumanniiand propose a potential role of the IL-17 pathway in generating a protective immune response.


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