Mass-spectral studies of binuclear metal complexes

The thermal decomposition of twenty-five cupric carboxylates was studied by mass spectrometry. In eleven cases volatile cuprous carboxylates (many of which have not been previously reported) were detected amongst the decomposition products. The cuprous carboxylates from acetic, propionic, n-butyric, isobutyric, difluoroacetic, trifluoroacetic, benzoic, p-fluorobenzoic, p-chlorobenzoic, o-chlorobenzoic, and pentafluorobenzoic acids were all found to be dimeric in the vapor phase. Two basically different fragmentation pathways can be proposed depending upon whether the copper salt is formed from an alkyl- or aryl-carboxylic acid. For the former, the spectra are dominated by even-electron fragment ions formed by initial loss of RCO2•from the molecular ion. For the latter, a parallel fragmentation pathway initiated by loss of CO2 from the molecular ion and migration of the aryl group to the metal is also present.

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SYNTHESIS, BIOLOGICAL STUDY, DNA INTERACTION OF MANNICH BASE METAL COMPLEXES DERIVED FROM BENZAMIDE

International Journal of Current Pharmaceutical Research ◽

10.22159/ijcpr.2021v13i6.1917 ◽

2021 ◽

pp. 60-64

Author(s):

SIVAKAMI SUDHASANKAR

Keyword(s):

Metal Complexes ◽

Mannich Base ◽

Dna Interaction ◽

Mannich Bases ◽

Molar Conductance ◽

Biological Study ◽

Spectral Studies ◽

Mass Spectral ◽

Calf Thymus ◽

Uv Visible

Objective: Coordination compounds occur widely in nature and they comprise a large share of current inorganic research. The Mannich reaction is a classic method for the preparation of Mannich bases, namely, β amino compounds, which are heterocyclic. Methods: A novel Mannich base of N-((3,4-dimethoxyphenyl)(2,5-dioxopyrrolidin-1-yl) methyl)benzamide and its coordination complexes with transition metals Mn and Co have been synthesized and characterized by elemental analysis, molar conductance, magnetic susceptibility measurements, UV-Visible, IR, NMR, and Mass spectral studies. Results: Based on the magnetic moment and UV-Visible spectral data, octahedral geometries were assigned for the metal complexes. The metal complexes were screened for antifungal activity. Conclusion: the metal complexes have shown good activity than the ligand. The binding of selected metal complexes with calf thymus DNA was investigated. It is found that the cobalt (II) metal complex of the ligand showed efficient DNA binding ability.

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Synthesis, Characterization and Biological Evaluation of Schiff Base Transition Metal Complexes Derived from 4-Nitrobenzene-1,2-diamine and 5-Chloroisatin

Asian Journal of Chemistry ◽

10.14233/ajchem.2020.22724 ◽

2020 ◽

Vol 32 (9) ◽

pp. 2324-2328

Author(s):

NETRA PAL SINGH ◽

KAUSHAL KUMAR ◽

GAJENDRA KUMAR ◽

ANUROOP KUMAR

Keyword(s):

Schiff Base ◽

Transition Metal ◽

Metal Complexes ◽

Transition Metal Complexes ◽

Magnetic Moments ◽

Biological Evaluation ◽

Molar Conductance ◽

Spectral Studies ◽

Mass Spectral ◽

Bacteria And Fungi

A series of transition metal complexes of the type [MLX2], where M = Mn(II), Fe(II), Co(II), Ni(II), X = Cl–/CH3COO– and L = Schiff base derived from 4-nitrobenzene-1,2-diamine and 5-chloroisatin have been synthesized and characterized by elemental analysis, molar conductance, IR, UV-visible, magnetic moments measurement, 1H & 13C NMR and mass spectral studies. On the basis of physico-chemical studies and spectral evaluation, an octahedral geometry have been proposed for all metal(II) complexes. The antimicrobial activity of ligand and its metal complexes have been additionally screened against bacteria and fungi. Metal(II) complexes show good activity as compared to ligand towards studied microorganisms and also metal complexes checked for their catalytic properties for benzoylation of phenol.

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Magnetic and Spectroscopic Studies of the Synthesized Metal Complexes of Bis(Pyridine-2-carbo) Hydrazide and Their Antimicrobial Studies

E-Journal of Chemistry ◽

10.1155/2012/521345 ◽

2012 ◽

Vol 9 (4) ◽

pp. 1835-1842 ◽

Cited By ~ 5

Author(s):

Netra Pal Singh ◽

Anu ◽

Jagvir Singh

Keyword(s):

Staphylococcus Aureus ◽

Metal Complexes ◽

Magnetic Moments ◽

Bacterial Species ◽

Spectroscopic Studies ◽

Fungal Species ◽

Molar Conductance ◽

Spectral Studies ◽

Mass Spectral ◽

Antimicrobial Studies

Cobalt(II), Nickel(II), Copper(II) and Manganese(II) complexes, having the general composition {M(L)2X2}, have been synthesized [where L= bis(pyridine-2-carbo) hydrazide(L), and X = Cl–]. All the Metal complexes reported here have been characterized by elemental analysis, molar conductance, magnetic moments, IR, electronic and mass spectral studies. All the complexes were found to have magnetic moments corresponding to unpaired electrons. The possible geometries of the complexes were assigned on the basis of electronic and infrared spectral studies. On the basis of molar conductance values the complexes show 1:2 electrolytic nature. Newly synthesized ligand and its Metal complexes have been screened againstStaphylococcus aureus(ATCC 25923),Staphylococcus aureus(ATCC 3160) bacterial species andCandida albicans(227) and Staphylococcus cereviscae (361) fungal species.

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