Generation of a mesoporous silica MSU shell onto solid core silica nanoparticles using a simple two-step sol–gel process

2011 ◽  
Vol 47 (26) ◽  
pp. 7476 ◽  
Author(s):  
Joachim Allouche ◽  
Jean-Charles Dupin ◽  
Danielle Gonbeau
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Sol Gel ◽  
Solid Core ◽  
Sol Gel Process

Green Synthesis of AgNPs Coated Mesoporous Silica Nanoparticles Using Tyrosine as Reducing/Stabilising Agent

2018 ◽  
Vol 928 ◽  
pp. 89-93 ◽  
Author(s):  
Waranya Ratirotjanakul ◽  
Tanapon Sioloetwong ◽  
Teeraporn Suteewong ◽  
Pramuan Tangboriboonrat
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
High Speed ◽  
Mesoporous Silica Nanoparticles ◽  
Drug Carrier ◽  
Sol Gel ◽  
Visible Absorption ◽  
Sol Gel Process ◽  
Phenolic Group ◽  
Uv Visible

A novel, simple and environmental friendly approach to fabricate silver nanoparticles (AgNPs) on mesoporous silica nanoparticles (MSNs) using tyrosine (Tyr) as biological reducing agent was developed. The functionalization of Tyr with MSNs (Tyr-MSNs) (150 nm in length) by the sol-gel process was confirmed by the characteristic peaks of amino, carboxyl and silanol groups appeared in FTIR spectrum and the change of the zeta potential from 0 mV at pH 2 to-60 mV at pH 12. Then, AgNPs were formed on the surface of Tyr-MSNs (Tyr-MSN@AgNPs) via only reducibility from phenolic group of Tyr and catalytic activity from base at room temperature. TEM images and UV-Visible absorption band at 420 nm supported the obtained AgNPs (18 nm at pH 11) were tightly bound to Tyr-MSNs even after centrifugation at high speed. These Tyr-MSN@AgNPs would be potentially used as drug carrier in biomedical applications.

Delocalization of electronic states in graphene oxide stabilised mesoporous silica nanoparticles revealed using photoluminescence

RSC Advances ◽  
2014 ◽  
Vol 4 (34) ◽  
pp. 17879-17883 ◽  
Author(s):  
Naveen Chandrasekaran ◽  
Santhana Sivabalan ◽  
Aswin Prathap ◽  
S. Mohan ◽  
R. Jagannathan
Keyword(s):  
Graphene Oxide ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Silica Aerogel ◽  
Mesoporous Silica Nanoparticles ◽  
Sol Gel ◽  
Electronic States ◽  
Coordination Complexes ◽  
Sol Gel Process ◽  
Graphene Oxide Sheets

Mesoporous silica aerogel obtained through a sol–gel process when surface treated with 2-D graphene oxide sheets reveals many fascinating features particularly, leading to multiple coordination complexes based on amide linkages.

Preparation of superhydrophobic silica nanoparticles by microwave assisted sol–gel process

2011 ◽  
Vol 61 (1) ◽  
pp. 8-13 ◽  
Author(s):  
A. Santiago ◽  
A. González ◽  
J. J. Iruin ◽  
M. J. Fernández-Berridi ◽  
L. Irusta
Keyword(s):  
Silica Nanoparticles ◽  
Sol Gel ◽  
Microwave Assisted ◽  
Sol Gel Process ◽  
Superhydrophobic Silica

scholarly journals Large Pore Mesoporous Silica and Organosilica Nanoparticles for Pepstatin A Delivery in Breast Cancer Cells

Molecules ◽  
2019 ◽  
Vol 24 (2) ◽  
pp. 332 ◽  
Author(s):  
Saher Rahmani ◽  
Jelena Budimir ◽  
Mylene Sejalon ◽  
Morgane Daurat ◽  
Dina Aggad ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Cancer Cells ◽  
Cathepsin D ◽  
Breast Cancer Cells ◽  
Potent Inhibitor ◽  
Mesoporous Silica Nanoparticles ◽  
Sol Gel ◽  
Pepstatin A

(1) Background: Nanomedicine has recently emerged as a new area of research, particularly to fight cancer. In this field, we were interested in the vectorization of pepstatin A, a peptide which does not cross cell membranes, but which is a potent inhibitor of cathepsin D, an aspartic protease particularly overexpressed in breast cancer. (2) Methods: We studied two kinds of nanoparticles. For pepstatin A delivery, mesoporous silica nanoparticles with large pores (LPMSNs) and hollow organosilica nanoparticles (HOSNPs) obtained through the sol–gel procedure were used. The nanoparticles were loaded with pepstatin A, and then the nanoparticles were incubated with cancer cells. (3) Results: LPMSNs were monodisperse with 100 nm diameter. HOSNPs were more polydisperse with diameters below 100 nm. Good loading capacities were obtained for both types of nanoparticles. The nanoparticles were endocytosed in cancer cells, and HOSNPs led to the best results for cancer cell killing. (4) Conclusions: Mesoporous silica-based nanoparticles with large pores or cavities are promising for nanomedicine applications with peptides.

Preparation and Characterization of Paclitaxel Imprinted Silica Nanoparticles

2011 ◽  
Vol 399-401 ◽  
pp. 1894-1897
Author(s):  
Jian Hua Li ◽  
Zong Jian Zheng ◽  
Shao Ping Fu ◽  
Jing Bo Zhu
Keyword(s):  
Silica Nanoparticles ◽  
Dissociation Constants ◽  
Sol Gel ◽  
Scatchard Analysis ◽  
Binding Properties ◽  
Imprinted Polymers ◽  
Sol Gel Process ◽  
Equilibrium Dissociation Constants ◽  
Equilibrium Dissociation

Highly selective molecularly imprinted layer-coated silica nanoparticles for paclitaxel were synthesized by molecular imprinting technique with a sol–gel process on the supporter of silica nanoparticles. The morphology of the obtained polymers was characterized by scanning electron microscopy (SEM). The binding properties of the imprinted polymers were evaluated through the equilibrium rebinding experiments. Scatchard analysis revealed that two classes of binding sites were formed in the imprinted polymers with equilibrium dissociation constants of 0.0509 g•L-1and 0.0094 g•L-1, respectively. Paclitaxel and its analogue were employed for selectivity tests. The results indicated that the imprinted polymers exhibited good selectivity and specificity toward paclitaxel.

Characterization of Nanostructured Silica as Carrier for Insecticides Deltamethrin, Pyriproxyfen, and Chlorpyrifos and Testing the Insecticidal Efficacy Against Trogoderma granarium (Coleoptera: Dermestidae) Larvae

2019 ◽  
Vol 113 (1) ◽  
pp. 511-517
Author(s):  
Masumeh Ziaee ◽  
Asgar Babamir-Satehi
Keyword(s):  
Electron Microscopy ◽  
Silica Nanoparticles ◽  
Sol Gel ◽  
Sem Analysis ◽  
Efficient Treatment ◽  
Trogoderma Granarium ◽  
Transmission Electron ◽  
Insecticidal Efficacy ◽  
Sol Gel Process ◽  
Nanostructured Silica

Abstract Nanostructured silica can be used as a carrier of pesticides to enhance stability and controlled release of agrochemicals with an effective concentration on target pests. Silica nanoparticles (SNPs) were synthesized by sol–gel process and employed as a carrier of three different insecticides including deltamethrin, pyriproxyfen, and chlorpyrifos. The SNPs were characterized by X-ray diffraction (XRD) and scanning electron microscopy (SEM) analysis and the insecticides-loaded in SNPs were characterized by transmission electron microscopy (TEM). The toxicity of insecticides alone and loaded in SNPs was evaluated against small and large larvae of Trogoderma granarium Everts on concrete surfaces. The immediate mortality was counted after 1, 3, and 7 d of exposure, and then surviving individuals were transferred to untreated surfaces for seven more days, with delayed mortality was recorded. Small larvae were more susceptible than large ones on all insecticide treatments. In addition, insecticides loaded in silica nanoparticles were more effective when compared with application of the insecticides alone. For immediate mortality, deltamethrin loaded in SNPs was the most efficient treatment causing 70.5% mortality on small and 55.5% mortality on large larvae after 7 d of exposure to the highest concentration. Pyriproxyfen loaded in SNPs caused low immediate mortality, but the mortality increased in delayed count indicated that the insecticide could control the larvae even after they have been removed from treated surfaces. It can be concluded that loading insecticides in SNPs could significantly increase their insecticidal efficiency, but this increase was compound-dependent.

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