Ultrasensitive electrochemical immunosensor for CA 15-3 using thionine-nanoporous gold–graphene as a platform and horseradish peroxidase-encapsulated liposomes as signal amplification

The Analyst ◽

10.1039/c2an35751h ◽

2012 ◽

Vol 137 (19) ◽

pp. 4440 ◽

Author(s):

Shenguang Ge ◽

Xiuling Jiao ◽

Dairong Chen

Keyword(s):

Horseradish Peroxidase ◽

Signal Amplification ◽

Electrochemical Immunosensor ◽

Nanoporous Gold

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Electrochemical immunosensor for HBe antigen detection based on a signal amplification strategy: The co-catalysis of horseradish peroxidase and nanoporous gold

Sensors and Actuators B Chemical ◽

10.1016/j.snb.2018.12.157 ◽

2019 ◽

Vol 284 ◽

pp. 296-304 ◽

Author(s):

Yachao Zhang ◽

Yan Gao ◽

Xueli Zhang ◽

Huiming Wang ◽

Tian Xia ◽

...

Keyword(s):

Horseradish Peroxidase ◽

Signal Amplification ◽

Electrochemical Immunosensor ◽

Antigen Detection ◽

Nanoporous Gold ◽

Hbe Antigen ◽

Amplification Strategy

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A novel electrochemical immunosensor based on Au nanoparticles and horseradish peroxidase signal amplification for ultrasensitive detection of α-fetoprotein

Biomedical Microdevices ◽

10.1007/s10544-018-0291-7 ◽

2018 ◽

Vol 20 (2) ◽

Author(s):

Dingqiang Lu ◽

Qiuda Xu ◽

Guangchang Pang ◽

Fuping Lu

Keyword(s):

Horseradish Peroxidase ◽

Signal Amplification ◽

Au Nanoparticles ◽

Electrochemical Immunosensor ◽

Ultrasensitive Detection

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Electrochemical immunosensor for human chorionic gonadotropin based on horseradish peroxidase–functionalized Prussian blue–carbon nanotubes/gold nanocomposites as labels for signal amplification

Electrochimica Acta ◽

10.1016/j.electacta.2010.12.003 ◽

2011 ◽

Vol 56 (5) ◽

pp. 1973-1980 ◽

Author(s):

Hongchuan Yang ◽

Ruo Yuan ◽

Yaqin Chai ◽

Huilan Su ◽

Ying Zhuo ◽

...

Keyword(s):

Carbon Nanotubes ◽

Horseradish Peroxidase ◽

Prussian Blue ◽

Chorionic Gonadotropin ◽

Human Chorionic Gonadotropin ◽

Signal Amplification ◽

Electrochemical Immunosensor ◽

Blue Carbon ◽

Gold Nanocomposites

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Electrochemical immunosensor for α-fetoprotein detection using ferroferric oxide and horseradish peroxidase as signal amplification labels

Analytical Biochemistry ◽

10.1016/j.ab.2014.08.016 ◽

2014 ◽

Vol 465 ◽

pp. 121-126 ◽

Author(s):

Huan Wang ◽

Xiaojian Li ◽

Kexia Mao ◽

Yan Li ◽

Bin Du ◽

...

Keyword(s):

Horseradish Peroxidase ◽

Signal Amplification ◽

Electrochemical Immunosensor ◽

Ferroferric Oxide

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A highly sensitive electrochemical immunosensor for hepatitis B virus surface antigen detection based on Hemin/G-quadruplex horseradish peroxidase-mimicking DNAzyme-signal amplification

Biosensors and Bioelectronics ◽

10.1016/j.bios.2017.02.039 ◽

2017 ◽

Vol 94 ◽

pp. 184-192 ◽

Author(s):

Negar Alizadeh ◽

Rahman Hallaj ◽

Abdollah Salimi

Keyword(s):

Hepatitis B Virus ◽

Hepatitis B ◽

Horseradish Peroxidase ◽

Surface Antigen ◽

Signal Amplification ◽

Electrochemical Immunosensor ◽

Virus Surface ◽

Highly Sensitive ◽

B Virus ◽

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Ultrasensitive electrochemical immunosensor for carbohydrate antigen 72-4 based on dual signal amplification strategy of nanoporous gold and polyaniline–Au asymmetric multicomponent nanoparticles

Biosensors and Bioelectronics ◽

10.1016/j.bios.2014.08.043 ◽

2015 ◽

Vol 64 ◽

pp. 51-56 ◽

Author(s):

Haixia Fan ◽

Zhankui Guo ◽

Liang Gao ◽

Yong Zhang ◽

Dawei Fan ◽

...

Keyword(s):

Signal Amplification ◽

Carbohydrate Antigen ◽

Electrochemical Immunosensor ◽

Nanoporous Gold ◽

Amplification Strategy ◽

Dual Signal Amplification

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Ultrasensitive electrochemical immunosensor for zeranol detection based on signal amplification strategy of nanoporous gold films and nano-montmorillonite as labels

Analytica Chimica Acta ◽

10.1016/j.aca.2012.11.009 ◽

2013 ◽

Vol 758 ◽

pp. 72-79 ◽

Author(s):

Rui Feng ◽

Yong Zhang ◽

He Li ◽

Dan Wu ◽

Xiaodong Xin ◽

...

Keyword(s):

Signal Amplification ◽

Electrochemical Immunosensor ◽

Nanoporous Gold ◽

Amplification Strategy

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Fabrication of Electrochemical Immunosensor Using Gold Nanoclusters as Signal Amplification Labels

CHINESE JOURNAL OF ANALYTICAL CHEMISTRY (CHINESE VERSION) ◽

10.3724/sp.j.1096.2013.30122 ◽

2013 ◽

Vol 41 (5) ◽

pp. 658

Author(s):

Hong-Ying LIU ◽

Jun-Jie ZHU

Keyword(s):

Signal Amplification ◽

Gold Nanoclusters ◽

Electrochemical Immunosensor

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Highly sensitive electrochemical immunosensor for the simultaneous detection of multiple tumor markers for signal amplification

Talanta ◽

10.1016/j.talanta.2021.122133 ◽

2021 ◽

Vol 226 ◽

pp. 122133

Author(s):

Na Wang ◽

Jing Wang ◽

Xiaoqing Zhao ◽

Hou Chen ◽

Hui Xu ◽

...

Keyword(s):

Tumor Markers ◽

Signal Amplification ◽

Simultaneous Detection ◽

Electrochemical Immunosensor ◽

Multiple Tumor ◽

Highly Sensitive

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Metal Nanoparticle and Quantum Dot Tags for Signal Amplification in Electrochemical Immunosensors for Biomarker Detection

Chemosensors ◽

10.3390/chemosensors9040085 ◽

2021 ◽

Vol 9 (4) ◽

pp. 85

Author(s):

Anton Popov ◽

Benediktas Brasiunas ◽

Asta Kausaite-Minkstimiene ◽

Almira Ramanaviciene

Keyword(s):

Signal Amplification ◽

Electrochemical Immunosensor ◽

Metal Nanoparticle ◽

Biomarker Detection ◽

Analytical Instruments ◽

Electrochemical Immunosensors ◽

Highly Sensitive ◽

Recent Developments ◽

Electrochemical Signal ◽

Detection Of Biomarkers

With the increasing importance of healthcare and clinical diagnosis, as well as the growing demand for highly sensitive analytical instruments, immunosensors have received considerable attention. In this review, electrochemical immunosensor signal amplification strategies using metal nanoparticles (MNPs) and quantum dots (Qdots) as tags are overviewed, focusing on recent developments in the ultrasensitive detection of biomarkers. MNPs and Qdots can be used separately or in combination with other nanostructures, while performing the function of nanocarriers, electroactive labels, or catalysts. Thus, different functions of MNPs and Qdots as well as recent advances in electrochemical signal amplification are discussed. Additionally, the methods most often used for antibody immobilization on nanoparticles, immunoassay formats, and electrochemical methods for indirect biomarker detection are overviewed.

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