Acetylene bridged porphyrin–monophthalocyaninato ytterbium(iii) hybrids with strong two-photon absorption and high singlet oxygen quantum yield

2012 ◽  
Vol 41 (15) ◽  
pp. 4536 ◽  
Author(s):  
Hanzhong Ke ◽  
Wenbin Li ◽  
Tao Zhang ◽  
Xunjin Zhu ◽  
Hoi-Lam Tam ◽  
...  
Keyword(s):  
Quantum Yield ◽  
Singlet Oxygen ◽  
Photon Absorption ◽  
Two Photon Absorption ◽  
Two Photon

scholarly journals Highly efficient singlet oxygen generation, two-photon photodynamic therapy and melanoma ablation by rationally designed mitochondria-specific near-infrared AIEgens

2020 ◽  
Vol 11 (9) ◽  
pp. 2494-2503 ◽  
Author(s):  
Zheng Zheng ◽  
Haixiang Liu ◽  
Shaodong Zhai ◽  
Haoke Zhang ◽  
Guogang Shan ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Singlet Oxygen ◽  
Near Infrared ◽  
Molecular Engineering ◽  
Photon Absorption ◽  
Oxygen Generation ◽  
Two Photon Absorption ◽  
Two Photon ◽  
Singlet Oxygen Generation ◽  
Highly Efficient

Mitochondria-targeted photosensitizers with highly efficient singlet oxygen generation, bright near-infrared AIE and good two-photon absorption are obtained through ingenious molecular engineering for cancer cell-selective photodynamic therapy.

Synthesis, DNA photocleavage, singlet oxygen photogeneration and two photon absorption properties of ruthenium-phenanthroline porphyrins

2015 ◽  
Vol 19 (09) ◽  
pp. 1046-1052 ◽  
Author(s):  
Ze-Bin Xu ◽  
Fa-Quan Yu ◽  
Fengshou Wu ◽  
Heng Zhang ◽  
Kai Wang ◽  
...  
Keyword(s):  
Singlet Oxygen ◽  
Cross Section ◽  
Therapeutic Agents ◽  
Photon Absorption ◽  
Quantum Yields ◽  
Absorption Properties ◽  
Dna Photocleavage ◽  
Two Photon Absorption ◽  
Two Photon ◽  
Photochemical Properties

Through a new synthetic route, three ruthenium-phenanthroline porphyrins (RPP1, RPP2 and RPP3) were prepared. Their photophysical and photochemical properties, such as DNA photocleavage activity, singlet-oxygen photogeneration and two-photon absorption (2PA) were evaluated. These porphyrins 1–3 had substantial photocleavage activities, with 71%, 74% and 38% observed at 20 μM. The porphyrins with different substituents on phenathroline group had similar singlet oxygen quantum yields, with ΦΔ values at 0.52, 0.47 and 0.41, respectively. The 2PA cross-section (σ(2)) values of RPP 1–3, measured by the Z-scan method, were calculated to be 152, 172 and 135 GM, respectively, which were around 5-fold higher than that of H2TPP . Thus, these porphyrins, with their good photocleavage activities, 1 O 2 quantum yields and high 2PA cross section, suggest great potential as photodynamic therapeutic agents.

Designing two-photon fluorescent probes based on the target-induced enhancement of the absorption cross-section

2014 ◽  
Vol 50 (76) ◽  
pp. 11139-11142 ◽  
Author(s):  
Lingyu Zeng ◽  
Shiyu Chen ◽  
Tian Xia ◽  
Cheng Zhong ◽  
Zhihong Liu
Keyword(s):  
Quantum Yield ◽  
Cross Section ◽  
Fluorescent Probes ◽  
Absorption Cross Section ◽  
Photon Absorption ◽  
Probe Design ◽  
Absorption Cross ◽  
Two Photon Absorption ◽  
Two Photon ◽  
New Strategy

We have reported a new strategy for two-photon probe design for the simultaneous target-induced enhancement of the two-photon absorption cross-section and quantum yield.

Diketopyrrolopyrrole-Porphyrin Conjugates with High Two-Photon Absorption and Singlet Oxygen Generation for Two-Photon Photodynamic Therapy

2014 ◽  
Vol 127 (1) ◽  
pp. 171-175 ◽  
Author(s):  
Julie Schmitt ◽  
Valérie Heitz ◽  
Angélique Sour ◽  
Frédéric Bolze ◽  
Hussein Ftouni ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Singlet Oxygen ◽  
Photon Absorption ◽  
Oxygen Generation ◽  
Two Photon Absorption ◽  
Two Photon ◽  
Singlet Oxygen Generation

Two-Photon Absorption Properties of New Fluorene-Based Singlet Oxygen Photosensitizers

2009 ◽  
Vol 113 (11) ◽  
pp. 4706-4711 ◽  
Author(s):  
Kevin D. Belfield ◽  
Mykhailo V. Bondar ◽  
Florencio E. Hernandez ◽  
Artëm E. Masunov ◽  
Ivan A. Mikhailov ◽  
...  
Keyword(s):  
Singlet Oxygen ◽  
Photon Absorption ◽  
Absorption Properties ◽  
Two Photon Absorption ◽  
Two Photon

scholarly journals Laser Induced Synthesis: Condensation of Acrylonitrile on Carvone

1988 ◽  
Vol 8 (2-4) ◽  
pp. 303-313
Author(s):  
R. Stringat ◽  
F. Lemaire ◽  
R. Fellous ◽  
A. M. Loiseau
Keyword(s):  
Quantum Yield ◽  
Absorption Band ◽  
Laser Irradiation ◽  
Quantum Efficiency ◽  
Photon Absorption ◽  
High Quantum Efficiency ◽  
Two Photon Absorption ◽  
Two Photon ◽  
Intermolecular Reaction ◽  
Absorption Channel

Laser irradiation of R(–) carvone in solution in acrylonitrile within the absorption band of its n−π* transition (≃350 nm) leads to the formation of cyclobutanic adducts, together with traces of camphocarvone.The carvone transformation is complete and appears with high quantum efficiency. The quantum yield for intermolecular reaction is intensity dependent (13–30%). This is ascribed to the fact that the reaction takes place via both a one and a two-photon absorption channel, the second being even more efficient.

scholarly journals Two-Photon Photodynamic Therapy by Water-Soluble Self-Assembled Conjugated Porphyrins

2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Kazuya Ogawa ◽  
Yoshiaki Kobuke
Keyword(s):  
Photodynamic Therapy ◽  
Singlet Oxygen ◽  
Cross Section ◽  
Water Soluble ◽  
Photon Absorption ◽  
Time Resolved ◽  
Two Photon Absorption ◽  
Two Photon ◽  
Luminescence Measurement ◽  
Water Soluble Porphyrin

Studies on two-photon absorption (2PA) photodynamic therapy (PDT) by using three water-soluble porphyrin self-assemblies consisting of ethynylene-linked conjugatedbis(imidazolylporphyrin) are reviewed. 2PA cross-section values in water were obtained by an open aperture Z-scan measurement, and values were extremely large compared with those of monomeric porphyrins such as hematoporphyrin. These compounds were found to generate singlet oxygen efficiently upon one- as well as two-photon absorption as demonstrated by the time-resolved luminescence measurement at the characteristic band of singlet oxygen at 1270 nm and by using its scavenger. Photocytotoxicities for HeLa cancer cells were examined and found to be as high as those of hematoporphyrin, demonstrating that these compounds are potential candidates for 2PA-photodynamic therapy agents.

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