Gold nanorods@mSiO2 with a smart polymer shell responsive to heat/near-infrared light for chemo-photothermal therapy

2012 ◽  
Vol 22 (31) ◽  
pp. 16095 ◽  
Author(s):  
Hongyan Tang ◽  
Shun Shen ◽  
Jia Guo ◽  
Baisong Chang ◽  
Xinguo Jiang ◽  
...  
Nanoscale ◽  
2015 ◽  
Vol 7 (36) ◽  
pp. 14854-14864 ◽  
Author(s):  
Bing Feng ◽  
Zhiai Xu ◽  
Fangyuan Zhou ◽  
Haijun Yu ◽  
Qianqian Sun ◽  
...  

Gold nanorods with cisplatin–polypeptide wrapping were developed for combinational photothermal therapy and chemotherapy of triple negative breast cancer.


Drug Delivery ◽  
2021 ◽  
Vol 28 (1) ◽  
pp. 1769-1784
Author(s):  
Zongjunlin Liu ◽  
Fang Xie ◽  
Jun Xie ◽  
Jianhao Chen ◽  
Yang Li ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Mary K. Popp ◽  
Imane Oubou ◽  
Colin Shepherd ◽  
Zachary Nager ◽  
Courtney Anderson ◽  
...  

Photothermal therapy (PTT) treatments have shown strong potential in treating tumors through their ability to target destructive heat preferentially to tumor regions. In this paper we demonstrate that PTT in a murine melanoma model using gold nanorods (GNRs) and near-infrared (NIR) light decreases tumor volume and increases animal survival to an extent that is comparable to the current generation of melanoma drugs. GNRs, in particular, have shown a strong ability to reach ablative temperatures quickly in tumors when exposed to NIR light. The current research tests the efficacy of GNRs PTT in a difficult and fast growing murine melanoma model using a NIR light-emitting diode (LED) light source. LED light sources in the NIR spectrum could provide a safer and more practical approach to photothermal therapy than lasers. We also show that the LED light source can effectively and quickly heatin vitroandin vivomodels to ablative temperatures when combined with GNRs. We anticipate that this approach could have significant implications for human cancer therapy.


Small ◽  
2008 ◽  
Vol 4 (7) ◽  
pp. 1001-1007 ◽  
Author(s):  
Takuro Niidome ◽  
Yasuyuki Akiyama ◽  
Kohei Shimoda ◽  
Takahito Kawano ◽  
Takeshi Mori ◽  
...  

2015 ◽  
Vol 51 (13) ◽  
pp. 2569-2572 ◽  
Author(s):  
Jie Yang ◽  
Ming-Hao Yao ◽  
Ming-Shuo Du ◽  
Rui-Mei Jin ◽  
Dong-Hui Zhao ◽  
...  

A hybrid platform with polypeptide-engineered functionalized gold nanorods has been designed for reversible presentation of immobilized bioactive ligands by near-infrared light.


2011 ◽  
Vol 152 ◽  
pp. e137-e139 ◽  
Author(s):  
Daxiang Cui ◽  
Peng Huang ◽  
Chunlei Zhang ◽  
Cengiz S. Ozkan ◽  
Bifeng Pan ◽  
...  

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