A near-infrared light-controlled system for reversible presentation of bioactive ligands using polypeptide-engineered functionalized gold nanorods

2015 ◽  
Vol 51 (13) ◽  
pp. 2569-2572 ◽  
Author(s):  
Jie Yang ◽  
Ming-Hao Yao ◽  
Ming-Shuo Du ◽  
Rui-Mei Jin ◽  
Dong-Hui Zhao ◽  
...  
Keyword(s):  
Gold Nanorods ◽  
Near Infrared ◽  
Infrared Light ◽  
Controlled System ◽  
Near Infrared Light ◽  
Bioactive Ligands ◽  
Hybrid Platform

A hybrid platform with polypeptide-engineered functionalized gold nanorods has been designed for reversible presentation of immobilized bioactive ligands by near-infrared light.

In Vivo Monitoring of Intravenously Injected Gold Nanorods Using Near‐Infrared Light

Small ◽  
2008 ◽  
Vol 4 (7) ◽  
pp. 1001-1007 ◽  
Author(s):  
Takuro Niidome ◽  
Yasuyuki Akiyama ◽  
Kohei Shimoda ◽  
Takahito Kawano ◽  
Takeshi Mori ◽  
...  
Keyword(s):  
Gold Nanorods ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
In Vivo Monitoring

Dendrimer-modified gold nanorods as efficient controlled gene delivery system under near-infrared light irradiation

2011 ◽  
Vol 152 ◽  
pp. e137-e139 ◽  
Author(s):  
Daxiang Cui ◽  
Peng Huang ◽  
Chunlei Zhang ◽  
Cengiz S. Ozkan ◽  
Bifeng Pan ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Delivery System ◽  
Gold Nanorods ◽  
Near Infrared ◽  
Light Irradiation ◽  
Infrared Light ◽  
Gene Delivery System ◽  
Near Infrared Light

scholarly journals An in vitro of radiation dose enhancement using gold nanorods and plasmonic photothermal therapy

2021 ◽  
Author(s):  
Daniel DiCenzo DiCenzo
Keyword(s):  
Radiation Dose ◽  
Ionizing Radiation ◽  
Gold Nanorods ◽  
Near Infrared ◽  
Infrared Light ◽  
Nuclear Localization Sequence ◽  
X Rays ◽  
Dose Enhancement ◽  
Near Infrared Light ◽  
Pc3 Cells

Gold nanoparticles (GNP) have been shown to highly absorb ionizing radiation compared to tissue. GNPs have also been shown to be high absorbers of non-ionizing radiation with a peak absorbance at a wavelength dependent on their shape and size. This study investigated radiation dose enhancement in PC3 cells when in the presence of gold nanorods (NR) and near infrared light (IR). The PC3 cells were incubated with either PEGylated NRs (PNR) or anti prostate stem cell antigen antibody with nuclear localization sequence peptide conjugated NRs (AbNR). They were exposed to near infrared light at a wavelength of 810 nm to achieve a temperature of 42 ºC to 43 ºC for 60 minutes. They were also exposed to 160 kVp x-rays. It was found that both targeted and non-targeted GNPs when exposed to radiation and near infrared light synergistically enhanced radiation dose. It was also found that AbNRs provide greater dose enhancement than PNRs.

Gold Nanorods Coated with Mesoporous Silica Shell as Drug Delivery System for Remote Near Infrared Light-Activated Release and Potential Phototherapy

Small ◽  
2015 ◽  
Vol 11 (19) ◽  
pp. 2323-2332 ◽  
Author(s):  
Ji Liu ◽  
Christophe Detrembleur ◽  
Marie-Claire De Pauw-Gillet ◽  
Stéphane Mornet ◽  
Christine Jérôme ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Drug Delivery System ◽  
Delivery System ◽  
Gold Nanorods ◽  
Near Infrared ◽  
Silica Shell ◽  
Infrared Light ◽  
Near Infrared Light

Gold nanorods@mSiO2 with a smart polymer shell responsive to heat/near-infrared light for chemo-photothermal therapy

2012 ◽  
Vol 22 (31) ◽  
pp. 16095 ◽  
Author(s):  
Hongyan Tang ◽  
Shun Shen ◽  
Jia Guo ◽  
Baisong Chang ◽  
Xinguo Jiang ◽  
...  
Keyword(s):  
Gold Nanorods ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Infrared Light ◽  
Polymer Shell ◽  
Near Infrared Light ◽  
Smart Polymer

Near-infrared light-responsive supramolecular nanovalve based on mesoporous silica-coated gold nanorods

2014 ◽  
Vol 5 (7) ◽  
pp. 2804 ◽  
Author(s):  
Hui Li ◽  
Li-Li Tan ◽  
Peng Jia ◽  
Qing-Lan Li ◽  
Yu-Long Sun ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Gold Nanorods ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light

Fabrication and optical stability of silanized gold nanorods as multifunctional transducers of near infrared light

2011 ◽  
Author(s):  
Fulvio Ratto ◽  
Paolo Matteini ◽  
Sonia Centi ◽  
Francesca Rossi ◽  
Franco Fusi ◽  
...  
Keyword(s):  
Gold Nanorods ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Optical Stability

scholarly journals PREPARATION AND CHARACTERIZATION OF A NEAR-INFRARED LIGHT RESPONSIVE MICROCAPSULE SYSTEM FOR CANCER THERAPY

2014 ◽  
Vol 07 (01) ◽  
pp. 1350037 ◽  
Author(s):  
YINGFENG DI ◽  
SISI CUI ◽  
YUEQING GU
Keyword(s):  
Cancer Therapy ◽  
Gold Nanorods ◽  
Self Assembly ◽  
Near Infrared ◽  
Infrared Light ◽  
Layer By Layer ◽  
Near Infrared Light ◽  
Nir Light ◽  
Alternative Material ◽  
Confocal Fluorescence Imaging

A novel near-infrared light responsive microcapsule system, gold nanorod-covered DOX-loaded hollow CaCO 3 microcapsule ( AuNR -HM-DOX) is developed for cancer therapy. The hollow CaCO 3 microcapsules were prepared based on the self-assembly between chitosan and sodium alginate on CaCO 3 particles via layer-by-layer technique, and then covered with gold nanorods to obtain the microcapsule system. Upon near-infrared (NIR) irradiation, microcapsule with gold nanorods can convert the absorbed NIR light into heat. Meanwhile, doxorubicin (DOX), a chemotherapy drug, is loaded into the microcapsule system via electrostatic adsorption for combined photothermal therapy and chemotherapy. Properties of AuNR -HM-DOX including grain diameter, optical spectra were characterized. Confocal fluorescence imaging was performed to observe the morphology of the capsules and existence of DOX in the core, confirming the successful loading of DOX. The release of DOX from the capsules under continuous NIR irradiation was investigated to evaluate the temperature responsiveness of AuNR -HM-DOX. Results indicate that AuNR -HM-DOX microcapsules possess uniform particle size and high light responsiveness. The combination of chemical and physical therapy of AuNR -HM-DOX features great potential as an adjuvant therapeutic alternative material for combined cancer therapy.

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