A device architecture for three-dimensional, patterned paper immunoassays

Lab on a Chip ◽  
2014 ◽  
Vol 14 (24) ◽  
pp. 4653-4658 ◽  
Author(s):  
Jeremy E. Schonhorn ◽  
Syrena C. Fernandes ◽  
Anjali Rajaratnam ◽  
Rachel N. Deraney ◽  
Jason P. Rolland ◽  
...  
2020 ◽  
Vol 9 (11) ◽  
pp. 668
Author(s):  
Zhenwu Wang ◽  
Benting Wan ◽  
Mengjie Han

The identification of underground geohazards is always a difficult issue in the field of underground public safety. This study proposes an interactive visualization framework for underground geohazard recognition on urban roads, which constructs a whole recognition workflow by incorporating data collection, preprocessing, modeling, rendering and analyzing. In this framework, two proposed sampling point selection methods have been adopted to enhance the interpolated accuracy for the Kriging algorithm based on ground penetrating radar (GPR) technology. An improved Kriging algorithm was put forward, which applies a particle swarm optimization (PSO) algorithm to optimize the Kriging parameters and adopts in parallel the Compute Unified Device Architecture (CUDA) to run the PSO algorithm on the GPU side in order to raise the interpolated efficiency. Furthermore, a layer-constrained triangulated irregular network algorithm was proposed to construct the 3D geohazard bodies and the space geometry method was used to compute their volume information. The study also presents an implementation system to demonstrate the application of the framework and its related algorithms. This system makes a significant contribution to the demonstration and understanding of underground geohazard recognition in a three-dimensional environment.


2014 ◽  
Vol 11 (04) ◽  
pp. 1350063 ◽  
Author(s):  
IFTIKHAR AHMED ◽  
RICK SIOW MONG GOH ◽  
ENG HUAT KHOO ◽  
KIM HUAT LEE ◽  
SIAW KIAN ZHONG ◽  
...  

The Lorentz–Drude model incorporated Maxwell equations are simulated by using the three-dimensional finite difference time domain (FDTD) method and the method is parallelized on multiple graphics processing units (GPUs) for plasmonics applications. The compute unified device architecture (CUDA) is used for GPU parallelization. The Lorentz–Drude (LD) model is used to simulate the dispersive nature of materials in plasmonics domain and the auxiliary differential equation (ADE) approach is used to make it consistent with time domain Maxwell equations. Different aspects of multiple GPUs for the FDTD method are presented such as comparison of different numbers of GPUs, transfer time in between them, synchronous, and asynchronous passing. It is shown that by using multiple GPUs in parallel fashion, significant reduction in the simulation time can be achieved as compared to the single GPU.


2014 ◽  
Vol 2014 ◽  
pp. 1-13 ◽  
Author(s):  
Manob Jyoti Saikia ◽  
Rajan Kanhirodan ◽  
Ram Mohan Vasu

We have developed a graphics processor unit (GPU-) based high-speed fully 3D system for diffuse optical tomography (DOT). The reduction in execution time of 3D DOT algorithm, a severely ill-posed problem, is made possible through the use of (1) an algorithmic improvement that uses Broyden approach for updating the Jacobian matrix and thereby updating the parameter matrix and (2) the multinode multithreaded GPU and CUDA (Compute Unified Device Architecture) software architecture. Two different GPU implementations of DOT programs are developed in this study: (1) conventional C language program augmented by GPU CUDA and CULA routines (C GPU), (2) MATLAB program supported by MATLAB parallel computing toolkit for GPU (MATLAB GPU). The computation time of the algorithm on host CPU and the GPU system is presented for C and Matlab implementations. The forward computation uses finite element method (FEM) and the problem domain is discretized into 14610, 30823, and 66514 tetrahedral elements. The reconstruction time, so achieved for one iteration of the DOT reconstruction for 14610 elements, is 0.52 seconds for a C based GPU program for 2-plane measurements. The corresponding MATLAB based GPU program took 0.86 seconds. The maximum number of reconstructed frames so achieved is 2 frames per second.


2011 ◽  
Vol 1359 ◽  
Author(s):  
Zhang-Lin Zhou ◽  
Jong-Souk Yeo ◽  
Qin Liu ◽  
Mary Parent ◽  
June Yang ◽  
...  

ABSTRACTReflective display technologies aim to enable the delivery of dynamic digital content to devices that have the look and feel of ink on paper. We are presenting herein a novel device architecture design and proprietary electrically addressable inks, which enable low power, disruptive, print-like full color reflective display that can exceed the chromaticity represented by the Specifications for Newsprint Advertising Production (SNAP) standard. We are approaching the challenge of generating bright high-quality reflective color images from the perspective of printing by stacking electro-optic layers of subtractive colorants to address every available color at every location. Using in-plane optical effects, our novel media technology provides fast switching between clear and color states. Thin, flexible electronic media based on this technology has been fabricated by imprinting three-dimensional micro-scale structures with a continuous roll-to-roll (R2R) manufacturing platform. HP’s combination of novel device architecture, proprietary inks, and R2R manufacturing platform enables the required attributes for electronic media such as flexibility, robustness, low power, transparency, print-quality color, and scalability at low cost. The structure property relationship of surfactants has been carried out; their impact on performance of display devices has been studied. These results have been applied to improve the performance of electronic inks. We have demonstrated 3-layer stacked segmented reflective display prototypes, as well as pixelated stacked color reflective display prototypes. The innovations described in this paper are applicable to electronic skins for customizable electronic surfaces and are currently being developed further for electronic paper and signage markets.


2010 ◽  
Vol 03 (01) ◽  
pp. 39-43 ◽  
Author(s):  
GUOTAO QUAN ◽  
TANGYOU SUN ◽  
YONG DENG

Three-dimensional image reconstruction with Feldkamp, Davis, and Kress (FDK) algorithm is the most time consuming part in Micro-CT. The parallel algorithm based on the computer cluster is capable of accelerating image reconstruction speed; however, the hardware is very expensive. In this paper, using the most current graphics processing units (GPU), we present a method based on common unified device architecture (CUDA) for speeding up the Micro-CT image reconstruction process. The most time consuming filtering and back-projection parts of the FDK algorithm are parallelized for the CUDA architecture. The CUDA-based reconstruction speed and image qualities are compared with CPU results for the projecting data of the Micro-CT system. The results show that the 3D image reconstruction speed based on CUDA is ten times faster than the speed with CPU. In conclusion the FDK algorithm based on CUDA for Micro-CT can reconstruct the 3D image right after the end of data acquisition.


1966 ◽  
Vol 25 ◽  
pp. 227-229 ◽  
Author(s):  
D. Brouwer

The paper presents a summary of the results obtained by C. J. Cohen and E. C. Hubbard, who established by numerical integration that a resonance relation exists between the orbits of Neptune and Pluto. The problem may be explored further by approximating the motion of Pluto by that of a particle with negligible mass in the three-dimensional (circular) restricted problem. The mass of Pluto and the eccentricity of Neptune's orbit are ignored in this approximation. Significant features of the problem appear to be the presence of two critical arguments and the possibility that the orbit may be related to a periodic orbit of the third kind.


Author(s):  
M. Boublik ◽  
W. Hellmann ◽  
F. Jenkins

The present knowledge of the three-dimensional structure of ribosomes is far too limited to enable a complete understanding of the various roles which ribosomes play in protein biosynthesis. The spatial arrangement of proteins and ribonuclec acids in ribosomes can be analysed in many ways. Determination of binding sites for individual proteins on ribonuclec acid and locations of the mutual positions of proteins on the ribosome using labeling with fluorescent dyes, cross-linking reagents, neutron-diffraction or antibodies against ribosomal proteins seem to be most successful approaches. Structure and function of ribosomes can be correlated be depleting the complete ribosomes of some proteins to the functionally inactive core and by subsequent partial reconstitution in order to regain active ribosomal particles.


Author(s):  
P.L. Moore

Previous freeze fracture results on the intact giant, amoeba Chaos carolinensis indicated the presence of a fibrillar arrangement of filaments within the cytoplasm. A complete interpretation of the three dimensional ultrastructure of these structures, and their possible role in amoeboid movement was not possible, since comparable results could not be obtained with conventional fixation of intact amoebae. Progress in interpreting the freeze fracture images of amoebae required a more thorough understanding of the different types of filaments present in amoebae, and of the ways in which they could be organized while remaining functional.The recent development of a calcium sensitive, demembranated, amoeboid model of Chaos carolinensis has made it possible to achieve a better understanding of such functional arrangements of amoeboid filaments. In these models the motility of demembranated cytoplasm can be controlled in vitro, and the chemical conditions necessary for contractility, and cytoplasmic streaming can be investigated. It is clear from these studies that “fibrils” exist in amoeboid models, and that they are capable of contracting along their length under conditions similar to those which cause contraction in vertebrate muscles.


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