Magnetic collagen fibers stabilized using functional iron oxide nanoparticles in non-aqueous medium

RSC Advances ◽  
2015 ◽  
Vol 5 (27) ◽  
pp. 20939-20944 ◽  
Author(s):  
C. Alliraja ◽  
J. Raghava Rao ◽  
P. Thanikaivelan
Keyword(s):  
Iron Oxide ◽  
Environmental Protection ◽  
Aqueous Medium ◽  
Iron Oxide Nanoparticles ◽  
Collagen Fibers ◽  
Oxide Nanoparticles

Thermostable magnetic collagen fibers prepared using functional iron oxide nanoparticles in heptane medium provide avenues for applications in environmental protection and leather making.

scholarly journals Incorporation of Superparamagnetic Iron Oxide Nanoparticles into Collagen Formulation for 3D Electrospun Scaffolds

Nanomaterials ◽  
2022 ◽  
Vol 12 (2) ◽  
pp. 181
Author(s):  
Manuel Estévez ◽  
Giorgia Montalbano ◽  
Alvaro Gallo-Cordova ◽  
Jesús G. Ovejero ◽  
Isabel Izquierdo-Barba ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Type I Collagen ◽  
Superparamagnetic Iron Oxide ◽  
Collagen Fibers ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Biological Assessment ◽  
Oxide Nanoparticles ◽  
Type I ◽  
Electrospun Scaffolds

Nowadays, there is an ever-increasing interest in the development of systems able to guide and influence cell activities for bone regeneration. In this context, we have explored for the first time the combination of type-I collagen and superparamagnetic iron oxide nanoparticles (SPIONs) to design magnetic and biocompatible electrospun scaffolds. For this purpose, SPIONs with a size of 12 nm were obtained by thermal decomposition and transferred to an aqueous medium via ligand exchange with dimercaptosuccinic acid (DMSA). The SPIONs were subsequently incorporated into type-I collagen solutions to prove the processability of the resulting hybrid formulation by means of electrospinning. The optimized method led to the fabrication of nanostructured scaffolds composed of randomly oriented collagen fibers ranging between 100 and 200 nm, where SPIONs resulted distributed and embedded into the collagen fibers. The SPIONs-containing electrospun structures proved to preserve the magnetic properties of the nanoparticles alone, making these matrices excellent candidates to explore the magnetic stimuli for biomedical applications. Furthermore, the biological assessment of these collagen scaffolds confirmed high viability, adhesion, and proliferation of both pre-osteoblastic MC3T3-E1 cells and human bone marrow-derived mesenchymal stem cells (hBM-MSCs).

Graphene oxide impregnated with iron oxide nanoparticles for the removal of atrazine from the aqueous medium

2018 ◽  
Vol 54 (16) ◽  
pp. 2653-2670 ◽  
Author(s):  
Murilo B. Andrade ◽  
Tássia R. T. Santos ◽  
Marcela Fernandes Silva ◽  
Marcelo F. Vieira ◽  
Rosângela Bergamasco ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Iron Oxide ◽  
Aqueous Medium ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles

Simplified synthesis of new GO-α-γ-Fe2O3-Sh adsorbent material composed of graphene oxide decorated with iron oxide nanoparticles applied for removing diuron from aqueous medium

2020 ◽  
Vol 8 (4) ◽  
pp. 103903 ◽  
Author(s):  
Murilo Barbosa de Andrade ◽  
Ana Carolina Sestito Guerra ◽  
Tássia Rhuna Tonial dos Santos ◽  
Luís Fernando Cusioli ◽  
Rodrigo de Souza Antônio ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Iron Oxide ◽  
Aqueous Medium ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles

scholarly journals Elucidating the morphological and structural evolution of iron oxide nanoparticles formed by sodium carbonate in aqueous medium

2012 ◽  
Vol 22 (25) ◽  
pp. 12498 ◽  
Author(s):  
Cristina Blanco-Andujar ◽  
Daniel Ortega ◽  
Quentin A. Pankhurst ◽  
Nguyen Thi Kim Thanh
Keyword(s):  
Iron Oxide ◽  
Aqueous Medium ◽  
Iron Oxide Nanoparticles ◽  
Sodium Carbonate ◽  
Structural Evolution ◽  
Oxide Nanoparticles

TARGETING CYCLIN B1 WITH ANTISENSE OLIGONUCLETOTIDES- COATED SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES

2018 ◽  
Vol 6 (10) ◽  
Author(s):  
Hosam Zaghloul ◽  
Doaa A. Shahin ◽  
Ibrahim El- Dosoky ◽  
Mahmoud E. El-awady ◽  
Fardous F. El-Senduny ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Cellular Uptake ◽  
Superparamagnetic Iron Oxide ◽  
Cyclin B1 ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Mcf7 Cells ◽  
M Phase ◽  
The Impact

Antisense oligonucleotides (ASO) represent an attractive trend as specific targeting molecules but sustain poor cellular uptake meanwhile superparamagnetic iron oxide nanoparticles (SPIONs) offer stability of ASO and improved cellular uptake. In the present work we aimed to functionalize SPIONs with ASO targeting the mRNA of Cyclin B1 which represents a potential cancer target and to explore its anticancer activity. For that purpose, four different SPIONs-ASO conjugates, S-M (1–4), were designated depending on the sequence of ASO and constructed by crosslinking carboxylated SPIONs to amino labeled ASO. The impact of S-M (1–4) on the level of Cyclin B1, cell cycle, ROS and viability of the cells were assessed by flowcytometry. The results showed that S-M3 and S-M4 reduced the level of Cyclin B1 by 35 and 36%, respectively. As a consequence to downregulation of Cyclin B1, MCF7 cells were shown to be arrested at G2/M phase (60.7%). S-M (1–4) led to the induction of ROS formation in comparison to the untreated control cells. Furthermore, S-M (1–4) resulted in an increase in dead cells compared to the untreated cells and SPIONs-treated cells. In conclusion, targeting Cyclin B1 with ASO-coated SPIONs may represent a specific biocompatible anticancer strategy.

Ferrozine Assay for Simple and Cheap Iron Analysis of Silica-Coated Iron Oxide Nanoparticles

2018 ◽  
Author(s):  
Hattie Ring ◽  
Zhe Gao ◽  
Nathan D. Klein ◽  
Michael Garwood ◽  
John C. Bischof ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Hydrofluoric Acid ◽  
Inductively Coupled Plasma ◽  
Silica Shell ◽  
Oxide Nanoparticles ◽  
Inductively Coupled ◽  
Digestion Process ◽  
Plasma Methods ◽  
Iron Analysis

The Ferrozinen assay is applied as an accurate and rapid method to quantify the iron content of iron oxide nanoparticles (IONPs) and can be used in biological matrices. The addition of ascorbic aqcid accelerates the digestion process and can penetrate an IONP core within a mesoporous and solid silica shell. This new digestion protocol avoids the need for hydrofluoric acid to digest the surrounding silica shell and provides and accessible alternative to inductively coupled plasma methods. With the updated digestion protocol, the quantitative range of the Ferrozine assay is 1 - 14 ppm. <br>

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