A ratiometric fluorescent probe for in vivo tracking of alkaline phosphatase level variation resulting from drug-induced organ damage

2015 ◽  
Vol 3 (6) ◽  
pp. 1042-1048 ◽  
Author(s):  
Xianfeng Hou ◽  
Qingxiang Yu ◽  
Fang Zeng ◽  
Junhui Ye ◽  
Shuizhu Wu
Keyword(s):  
Alkaline Phosphatase ◽  
Fluorescent Probe ◽  
Alkaline Phosphatase Level ◽  
Organ Damage ◽  
Level Variation ◽  
Serum Samples ◽  
Drug Induced ◽  
Ratiometric Fluorescent Probe

The ratiometric fluorescent probe discussed herein can detect ALP levels in clinical serum samples, and spatially map endogenous ALP level variations, which occur as a result of drug induced organ damage.

Lighting up alkaline phosphatase in drug-induced liver injury using a new chemiluminescence resonance energy transfer nanoprobe

2018 ◽  
Vol 54 (88) ◽  
pp. 12479-12482 ◽  
Author(s):  
Xueting Liu ◽  
Nannan Fan ◽  
Lijie Wu ◽  
Chuanchen Wu ◽  
Yongqing Zhou ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Energy Transfer ◽  
Liver Injury ◽  
Alkaline Phosphatase Level ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Drug Induced ◽  
Drug Induced Liver Injury

Ultra-sensitive imaging of the alkaline phosphatase levelin vivoin drug-induced liver injury with a new chemiluminescence resonance energy transfer nanoprobe.

The development of a hemicyanine-based ratiometric CO fluorescent probe with a long emission wavelength and its applications for imaging CO in vitro and in vivo

2020 ◽  
Vol 44 (28) ◽  
pp. 12107-12112 ◽  
Author(s):  
Yunyan Zhang ◽  
Xiuqi Kong ◽  
Yonghe Tang ◽  
Min Li ◽  
Yaguang Yin ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Living Cells ◽  
Emission Wavelength ◽  
Long Wavelength ◽  
Wavelength Emission ◽  
Ratiometric Fluorescent Probe

A novel ratiometric fluorescent probe, Hcy-CO, with long-wavelength emission was developed for visualizing CO in living cells and zebrafish.

Rational modulation of coumarin–hemicyanine platform based on OH substitution for higher selective detection of hypochlorite

2020 ◽  
Vol 56 (8) ◽  
pp. 1219-1222 ◽  
Author(s):  
Jin-Shuai Lan ◽  
Li Liu ◽  
Rui-Feng Zeng ◽  
Yan-Hong Qin ◽  
Yun Liu ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
High Selectivity ◽  
Selective Detection ◽  
Ratiometric Fluorescent Probe

A NIR and ratiometric fluorescent probe was developed to quantitate arthritis-dependent HOCl production in vivo with high selectivity and sensitivity.

Near-infrared mito-specific fluorescent probe for ratiometric detection and imaging of alkaline phosphatase activity with high sensitivity

2019 ◽  
Vol 7 (3) ◽  
pp. 443-450 ◽  
Author(s):  
Qian Zhang ◽  
Shasha Li ◽  
Caixia Fu ◽  
Yuzhe Xiao ◽  
Peng Zhang ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Phosphatase Activity ◽  
Fluorescent Probe ◽  
Alkaline Phosphatase Activity ◽  
Near Infrared ◽  
High Sensitivity ◽  
Cyanine Dye ◽  
Intracellular Imaging ◽  
Ratiometric Detection ◽  
Ratiometric Fluorescent Probe

A NIR ratiometric fluorescent probe based on cyanine dye was developed for detecting and intracellular imaging of ALP activity with high sensitivity.

A novel ratiometric fluorescent probe based on thienocoumarin and its application for the selective detection of hypochlorite in real water samples and in vivo

2020 ◽  
Vol 44 (16) ◽  
pp. 6232-6237 ◽  
Author(s):  
Lei Shi ◽  
Huijuan Yu ◽  
Xianqing Zeng ◽  
Sheng Yang ◽  
Shengzhao Gong ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Water Samples ◽  
Selective Detection ◽  
Emission Ratio ◽  
Real Water Samples ◽  
Ratiometric Fluorescent Probe

A novel ratiometric fluorescent probe based on thieno[3,2-c]coumarin has been prepared for sensing hypochlorite, which could exhibit a large emission shift and a 338-fold emission ratio (I470/I640).

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