A TICT based NIR-fluorescent probe for human serum albumin: a pre-clinical diagnosis in blood serum

2016 ◽  
Vol 52 (6) ◽  
pp. 1182-1185 ◽  
Author(s):  
Shahi Imam Reja ◽  
Imran A. Khan ◽  
Vandana Bhalla ◽  
Manoj Kumar
Keyword(s):  
Detection Limit ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Blood Serum ◽  
Blood Plasma ◽  
Human Serum ◽  
Fluorescent Probe ◽  
Clinical Diagnosis ◽  
Fluorescence Enhancement ◽  
In Blood Plasma

A TICT based NIR-fluorescent probe3has been designed and synthesized which selectively detects HSA with fluorescence enhancement in blood plasma with a detection limit of 11 nM among the various proteins, nucleotides and thiols tested.

Insights into graphene oxide interaction with human serum albumin in isolated state and in blood plasma

2021 ◽  
Vol 175 ◽  
pp. 19-29
Author(s):  
Stefka G. Taneva ◽  
Sashka Krumova ◽  
Ferenc Bogár ◽  
András Kincses ◽  
Svetozar Stoichev ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Blood Plasma ◽  
Human Serum ◽  
In Blood Plasma

THE PENETRATION OF IODINE-LABELLED FOLLICLE-STIMULATING HORMONE AND ALBUMIN INTO THE SEMINIFEROUS TUBULES OF SHEEP AND RATS

1972 ◽  
Vol 54 (1) ◽  
pp. 67-77 ◽  
Author(s):  
B. P. SETCHELL ◽  
A. L. C. WALLACE
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Blood Plasma ◽  
Human Serum ◽  
Total Protein ◽  
Follicle Stimulating Hormone ◽  
Volume Of Distribution ◽  
Rete Testis ◽  
Seminiferous Tubules ◽  
In Blood Plasma

SUMMARY The entry of 125I-labelled ovine follicle-stimulating hormone (FSH) and human serum albumin into the seminiferous tubules of rams has been studied by measuring radioactivity in blood plasma and rete testis fluid after an intravenous injection of the labelled protein. After the injection of FSH, radioactivity/mg total protein in rete testis fluid exceeded that in blood plasma from the first day onwards, but after the injection of human serum albumin, radioactivity/mg total protein in rete testis fluid only reached that in plasma after 4–5 days and never exceeded it. Protein-bound radioactivity disappeared from the blood more quickly after an injection of FSH than after an injection of albumin. The volume of distribution for ovine FSH in the testes of rats was greater than that for human serum albumin. The volume of distribution for FSH was greater, in absolute terms, in the testes with the efferent ducts ligated 24 h previously than in the contralateral control testes when the FSH was injected at the time of efferent duct ligation. The volume of distribution for albumin was slightly less in the ligated testes than in the control testes. This suggests that FSH but not albumin had penetrated into the fluid trapped inside the testis. The liver and kidney had much higher concentrations of protein-bound radioactivity per unit weight than did the testis after the injection of FSH, so it does not seem that FSH is selectively taken up by the testis.

Interaction between a novel intramolecular charge transfer fluorescent probe PFEP and human serum albumin

2010 ◽  
Vol 21 (4) ◽  
pp. 480-483 ◽  
Author(s):  
Dong Ju ◽  
Sheng Mei Song ◽  
Yan Bo Wu ◽  
Shao Min Shuang ◽  
Chuan Dong
Keyword(s):  
Charge Transfer ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Fluorescent Probe ◽  
Intramolecular Charge Transfer

A fluorescent probe for butyrylcholinesterase activity in human serum based on a fluorophore with specific binding affinity for human serum albumin

2019 ◽  
Vol 55 (97) ◽  
pp. 14574-14577 ◽  
Author(s):  
Soyeon Yoo ◽  
Min Su Han
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Fluorescent Probe ◽  
Binding Affinity ◽  
Specific Binding ◽  
Turn On ◽  
High Binding ◽  
Butyrylcholinesterase Activity ◽  
High Binding Affinity

We report a novel turn-on sensing probe for the detection of butyrylcholinesterase activity in human serum using a fluorophore with high binding affinity for HSA.

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