Two-photon polymerization microfabrication of hydrogels: an advanced 3D printing technology for tissue engineering and drug delivery

2015 ◽  
Vol 44 (15) ◽  
pp. 5031-5039 ◽  
Author(s):  
Jin-Feng Xing ◽  
Mei-Ling Zheng ◽  
Xuan-Ming Duan
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
High Resolution ◽  
3D Printing ◽  
Printing Technology ◽  
3D Printing Technology ◽  
Two Photon ◽  
Nano Scale ◽  
Two Photon Polymerization

Arbitrary and ultraprecise 3D hydrogels with high resolution on micro/nano scale can be produced by two-photon polymerization microfabrication as an advanced 3D printing technology.

scholarly journals Nanoscale 3D printing of hydrogels for cellular tissue engineering

2018 ◽  
Vol 6 (15) ◽  
pp. 2187-2197 ◽  
Author(s):  
Shangting You ◽  
Jiawen Li ◽  
Wei Zhu ◽  
Claire Yu ◽  
Deqing Mei ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
3D Printing ◽  
Cellular Tissue ◽  
Two Photon ◽  
Two Photon Polymerization

Two-photon polymerization enables nanoscale 3D printing of hydrogels.

3D Printing Technology in Drug Delivery: Recent Progress and Application

2019 ◽  
Vol 24 (42) ◽  
pp. 5039-5048 ◽  
Author(s):  
Sabna Kotta ◽  
Anroop Nair ◽  
Nimer Alsabeelah
Keyword(s):  
Drug Delivery ◽  
3D Printing ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Pharmaceutical Manufacturing ◽  
Layer By Layer ◽  
Printing Technology ◽  
Drug Dosing ◽  
3D Printing Technology ◽  
3D Printed

Background: 3D printing technology is a new chapter in pharmaceutical manufacturing and has gained vast interest in the recent past as it offers significant advantages over traditional pharmaceutical processes. Advances in technologies can lead to the design of suitable 3D printing device capable of producing formulations with intended drug release. Methods: This review summarizes the applications of 3D printing technology in various drug delivery systems. The applications are well arranged in different sections like uses in personalized drug dosing, complex drugrelease profiles, personalized topical treatment devices, novel dosage forms and drug delivery devices and 3D printed polypills. Results: This niche technology seems to be a transformative tool with more flexibility in pharmaceutical manufacturing. Typically, 3D printing is a layer-by-layer process having the ability to fabricate 3D formulations by depositing the product components by digital control. This additive manufacturing process can provide tailored and individualized dosing for treatment of patients different backgrounds with varied customs and metabolism pattern. In addition, this printing technology has the capacity for dispensing low volumes with accuracy along with accurate spatial control for customized drug delivery. After the FDA approval of first 3D printed tablet Spritam, the 3D printing technology is extensively explored in the arena of drug delivery. Conclusion: There is enormous scope for this promising technology in designing various delivery systems and provides customized patient-compatible formulations with polypills. The future of this technology will rely on its prospective to provide 3D printing systems capable of manufacturing personalized doses. In nutshell, the 3D approach is likely to revolutionize drug delivery systems to a new level, though need time to evolve.

scholarly journals 3D-Printed Biopolymers for Tissue Engineering Application

2014 ◽  
Vol 2014 ◽  
pp. 1-13 ◽  
Author(s):  
Xiaoming Li ◽  
Rongrong Cui ◽  
Lianwen Sun ◽  
Katerina E. Aifantis ◽  
Yubo Fan ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
3D Printing ◽  
Three Dimensional ◽  
Engineering Application ◽  
Tissue Engineering Application ◽  
Printing Technology ◽  
3D Printing Technology ◽  
Potential Applications ◽  
3D Printed ◽  
Dimensional Object

3D printing technology has recently gained substantial interest for potential applications in tissue engineering due to the ability of making a three-dimensional object of virtually any shape from a digital model. 3D-printed biopolymers, which combine the 3D printing technology and biopolymers, have shown great potential in tissue engineering applications and are receiving significant attention, which has resulted in the development of numerous research programs regarding the material systems which are available for 3D printing. This review focuses on recent advances in the development of biopolymer materials, including natural biopolymer-based materials and synthetic biopolymer-based materials prepared using 3D printing technology, and some future challenges and applications of this technology are discussed.

scholarly journals 3D Printing Technology: The Impetus Concept in the Drug Delivery

2019 ◽  
Vol Volume-3 (Issue-4) ◽  
pp. 870-873
Author(s):  
Hardeep Singh Bambra ◽  
Mohd Mazhar ◽  
Keyword(s):  
Drug Delivery ◽  
3D Printing ◽  
Printing Technology ◽  
3D Printing Technology

scholarly journals 3D Printing of large-scale and highly porous biodegradable tissue engineering scaffolds from poly(trimethylene-carbonate) using two-photon-polymerization

2020 ◽  
Vol 12 (4) ◽  
pp. 045036
Author(s):  
Gregor Weisgrab ◽  
Olivier Guillaume ◽  
Zhengchao Guo ◽  
Patrick Heimel ◽  
Paul Slezak ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
3D Printing ◽  
Large Scale ◽  
Trimethylene Carbonate ◽  
Tissue Engineering Scaffolds ◽  
Two Photon ◽  
Highly Porous ◽  
Two Photon Polymerization

Pharmaceutical Product Development Exploiting 3D Printing Technology: Conventional to Novel Drug Delivery System

2019 ◽  
Vol 24 (42) ◽  
pp. 5029-5038 ◽  
Author(s):  
Md. Shoaib Alam ◽  
Ayesha Akhtar ◽  
Iftikhar Ahsan ◽  
Sheikh Shafiq-un-Nabi
Keyword(s):  
Drug Delivery ◽  
3D Printing ◽  
Personalized Medicine ◽  
Drug Delivery System ◽  
Delivery System ◽  
Printing Technology ◽  
3D Printing Technology ◽  
3D Printed ◽  
Novel Drug Delivery System ◽  
Novel Drug

Background: 3D printed pharmaceutical products are revolutionizing the pharmaceutical industry as a prospective mean to achieve a personalized method of treatments acquired to the specially designed need of each patient. It will depend upon age, weight, concomitants, pharmacogenetics and pharmacokinetic profile of the patient and thus transforming the current pharmaceutical market as a potential alternative to conventional medicine. 3D printing technology is getting more consideration in new medicine formulation development as a modern and better alternative to control many challenges associated with conventional medicinal products. There are many advantages of 3D printed medicines which create tremendous opportunities for improving the acceptance, accuracy and effectiveness of these medicines. In 2015, United State Food and Drug Administration has approved the first 3D printed tablet (Spritam®) and had shown the emerging importance of this technology. Methods: This review article summarizes as how in-depth knowledge of drugs and their manufacturing processes can assist to manage different strategies for various 3D printing methods. The principal goal of this review is to provide a brief introduction about the present techniques employed in tech -medicine evolution from conventional to a novel drug delivery system. Results: It is evidenced that through its unparalleled advantages of high-throughput, versatility, automation, precise spatial control and fabrication of hierarchical structures, the implementation of 3D printing for the expansion and delivery of controlled drugs acts as a pivotal role. Conclusion: 3D printing technology has an extraordinary ability to provide elasticity in the manufacturing and designing of composite products that can be utilized in programmable and personalized medicine. Personalized medicine helps in improving drug safety and minimizes side effects such as toxicity to individual human being which is associated with unsuitable drug dose.

Importance of 3D Printing Technology in Medical Fields

2019 ◽  
pp. 21-40
Author(s):  
Ranjit Barua ◽  
Sudipto Datta ◽  
Amit Roychowdhury ◽  
Pallab Datta
Keyword(s):  
Tissue Engineering ◽  
Additive Manufacturing ◽  
3D Printing ◽  
New Technology ◽  
Three Dimensional ◽  
Layer By Layer ◽  
Medical Field ◽  
Printing Technology ◽  
3D Printing Technology ◽  
Proper Material

Three-dimensional or 3D printing technology is a growing interest in medical fields like tissue engineering, dental, drug delivery, prosthetics, and implants. It is also known as the additive manufacturing (AM) process because the objects are done by extruding or depositing the material layer by layer, and the material may be like biomaterials, plastics, living cells, or powder ceramics. Specially in the medical field, this new technology has importance rewards in contrast with conventional technologies, such as the capability to fabricate patient-explicit difficult components, desire scaffolds for tissue engineering, and proper material consumption. In this chapter, different types of additive manufacturing (AM) techniques are described that are applied in the medical field, especially in community health and precision medicine.

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