Approaches to reduce the glycemic response of gluten-free products: in vivo and in vitro studies

This article aims to discuss the current approaches used to reduce the postprandial glycemic response (GR) of starchy gluten-free products (GFP) and to provide some further prospects.

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Pigmented Corn Varieties as Functional Ingredients for Gluten-Free Products

Foods ◽

10.3390/foods10081770 ◽

2021 ◽

Vol 10 (8) ◽

pp. 1770

Author(s):

Francesca Colombo ◽

Chiara Di Lorenzo ◽

Katia Petroni ◽

Marco Silano ◽

Roberto Pilu ◽

...

Keyword(s):

Oxidative Stress ◽

Antioxidant Properties ◽

Chemical Characterization ◽

In Vivo Studies ◽

Gluten Free ◽

Cell Agglutination ◽

Free Products ◽

Phenolic Profile

Oxidative stress, one among the several factors responsible for the gluten toxicity in celiac disease, together with inflammation and duodenal mucosal injury, are only partially reduced by the gluten-free diet. Thanks to their phenolic profile, the pigmented varieties of corn could be an interesting source of dietary antioxidants for the formulation of new gluten-free ingredients. The aim of this research was: (1) to characterize the phenolic profile and the associated antioxidant properties of corn samples with different pigmentation, using spectrophotometric and chromatographic techniques and (2) to assess the stability of anthocyanins during the gastro-intestinal digestion. The pigmented varieties showed a significantly higher content of polyphenols compared to the common yellow varieties and, as a consequence, a higher antioxidant activity. Although corn is among the cereals most frequently used in gluten-free products, it can produce an inflammatory response in some celiac patients. Therefore, after the chemical characterization, the safety of the pigmented varieties for celiac patients was confirmed using different in vitro models (cell agglutination test and the measure of transepithelial electrical resistance). Although in vivo studies are necessary, the data collected in this study underline that the pigmented corn could have a role in reducing the oxidative stress at the intestinal level in celiac subjects.

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Abnormal Sensitivity of Cortisol-Producing Adrenocortical Adenomas to Serotonin: In Vivo and in Vitro Studies

Yearbook of Endocrinology ◽

10.1016/s0084-3741(08)70169-0 ◽

2007 ◽

Vol 2007 ◽

pp. 358-361

Author(s):

D.E. Schteingart

Keyword(s):

In Vitro Studies ◽

Adrenocortical Adenomas

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The Venom of the Boomslang (Dispholidus Typus): In Vivo and in Vitro Studies

Thrombosis and Haemostasis ◽

10.1055/s-0038-1653532 ◽

1969 ◽

Vol 21 (02) ◽

pp. 234-244 ◽

Cited By ~ 5

Author(s):

N Mackay ◽

J.C Ferguson ◽

Antonia Bagshawe ◽

A.T.T Forrester ◽

G.P Mcnicol

Keyword(s):

In Vitro Studies

SummaryAn account is given of the effects of boomslang venom in man. Evidence was found of a fibrinolytic state apparently secondary to the coagulant action of the venom. These features rapidly responded to the administration of specific antivenom. In vitro studies, using a homogenate of boomslang parotids, confirmed the coagulant properties of the venom and showed them to be of much greater potency than the proteolytic actions.

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The phytoestrogen biochanin a attenuates acute cardiac allograft rejection without affecting the reproductive system – In vivo and in vitro studies

The Thoracic and Cardiovascular Surgeon ◽

10.1055/s-2004-816777 ◽

2004 ◽

Vol 52 (S 1) ◽

Author(s):

S Schrepfer ◽

T Deuse ◽

F Koch-Nolte ◽

H Sch�fer ◽

H Reichenspurner

Keyword(s):

Reproductive System ◽

Allograft Rejection ◽

Cardiac Allograft ◽

In Vitro Studies ◽

Biochanin A ◽

Cardiac Allograft Rejection

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Effect of X-irradiation on gene expression of rat liver chemokines: in vivo and in vitro studies

Zeitschrift für Gastroenterologie ◽

10.1055/s-2008-1037499 ◽

2008 ◽

Vol 46 (01) ◽

Cited By ~ 1

Author(s):

F Moriconi ◽

H Christiansen ◽

N Sheikh ◽

J Dudas ◽

...

Keyword(s):

Gene Expression ◽

Rat Liver ◽

In Vitro Studies ◽

X Irradiation

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Ciamexon in low-dose streptozotocin induced diabetes mellitus. In vivo and in vitro studies

Acta Endocrinologica ◽

10.1530/acta.0.111s120 ◽

1986 ◽

Vol 113 (1_Suppl) ◽

pp. S120-S121

Author(s):

TH. LINN ◽

H. GERMANN ◽

B. HERING ◽

R. BRETZEL ◽

K. FEDERLIN

Keyword(s):

Diabetes Mellitus ◽

Low Dose ◽

In Vitro Studies ◽

Streptozotocin Induced Diabetes

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Delayed hypersensitivity to tetanus toxoid in man: in vivo and in vitro studies

Pathology ◽

10.3109/00313028309085161 ◽

1983 ◽

Vol 15 (4) ◽

pp. 369-372 ◽

Cited By ~ 15

Author(s):

Christine Johnson ◽

R.S. Walls ◽

A. Ruwoldt

Keyword(s):

Tetanus Toxoid ◽

In Vitro Studies ◽

Delayed Hypersensitivity

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Transplantation of Adipose-derived Cells for Periodontal Regeneration: A Systematic Review

Current Stem Cell Research & Therapy ◽

10.2174/1574888x13666181105144430 ◽

2019 ◽

Vol 14 (6) ◽

pp. 504-518 ◽

Cited By ~ 3

Author(s):

Dilcele Silva Moreira Dziedzic ◽

Bassam Felipe Mogharbel ◽

Priscila Elias Ferreira ◽

Ana Carolina Irioda ◽

Katherine Athayde Teixeira de Carvalho

Keyword(s):

Systematic Review ◽

Animal Models ◽

Platelet Rich Plasma ◽

Periodontal Regeneration ◽

In Vitro Studies ◽

In Vivo Studies ◽

Cell Sources ◽

Study Designs

This systematic review evaluated the transplantation of cells derived from adipose tissue for applications in dentistry. SCOPUS, PUBMED and LILACS databases were searched for in vitro studies and pre-clinical animal model studies using the keywords “ADIPOSE”, “CELLS”, and “PERIODONTAL”, with the Boolean operator “AND”. A total of 160 titles and abstracts were identified, and 29 publications met the inclusion criteria, 14 in vitro and 15 in vivo studies. In vitro studies demonstrated that adipose- derived cells stimulate neovascularization, have osteogenic and odontogenic potential; besides adhesion, proliferation and differentiation on probable cell carriers. Preclinical studies described improvement of bone and periodontal healing with the association of adipose-derived cells and the carrier materials tested: Platelet Rich Plasma, Fibrin, Collagen and Synthetic polymer. There is evidence from the current in vitro and in vivo data indicating that adipose-derived cells may contribute to bone and periodontal regeneration. The small quantity of studies and the large variation on study designs, from animal models, cell sources and defect morphology, did not favor a meta-analysis. Additional studies need to be conducted to investigate the regeneration variability and the mechanisms of cell participation in the processes. An overview of animal models, cell sources, and scaffolds, as well as new perspectives are provided for future bone and periodontal regeneration study designs.

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