scholarly journals A multifunctional role of trialkylbenzenes for the preparation of aqueous colloidal mesostructured/mesoporous silica nanoparticles with controlled pore size, particle diameter, and morphology

Nanoscale ◽  
2015 ◽  
Vol 7 (46) ◽  
pp. 19557-19567 ◽  
Author(s):  
Hironori Yamada ◽  
Hiroto Ujiie ◽  
Chihiro Urata ◽  
Eisuke Yamamoto ◽  
Yusuke Yamauchi ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Pore Size ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Particle Diameter ◽  
Size Particle ◽  
Judicious Choice

A judicious choice of trialkylbenzenes is critical to control the pore size, particle diameter, and morphology of aqueous colloidal mesoporous silica nanoparticles.

Blood clot initiation by mesoporous silica nanoparticles: dependence on pore size or particle size?

2016 ◽  
Vol 4 (44) ◽  
pp. 7146-7154 ◽  
Author(s):  
Zihao Chen ◽  
Fan Li ◽  
Changjun Liu ◽  
Jing Guan ◽  
Xiao Hu ◽  
...  
Keyword(s):  
Particle Size ◽  
Mesoporous Silica ◽  
Pore Size ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Blood Clot

The hemostatic efficiency of mesoporous silica nanoparticles depends on pore size more than particle size, and biocompatibility is more related to particle size.

scholarly journals Effects of pore size on in vitro and in vivo anticancer efficacies of mesoporous silica nanoparticles

RSC Advances ◽  
2018 ◽  
Vol 8 (43) ◽  
pp. 24633-24640 ◽  
Author(s):  
Jie Li ◽  
Suqin Shen ◽  
Fei Kong ◽  
Ting Jiang ◽  
Cui Tang ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Pore Size ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Pore Sizes

MSN with suitable pore sizes achieved an outstanding performance for in vitro and in vivo antitumor efficacies.

scholarly journals Role of mesoporous silica nanoparticles for the drug delivery applications

2020 ◽  
Vol 7 (10) ◽  
pp. 102002
Author(s):  
Baranya Murugan ◽  
Suresh Sagadevan ◽  
Anita Lett J ◽  
Is Fatimah ◽  
Kamrun Nahar Fatema ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Drug Delivery Applications

On the role of the colloidal stability of mesoporous silica nanoparticles as gene delivery vectors

2011 ◽  
Vol 13 (9) ◽  
pp. 4097-4108 ◽  
Author(s):  
Virginia Cebrián ◽  
Clara Yagüe ◽  
Manuel Arruebo ◽  
Francisco M. Martín-Saavedra ◽  
Jesus Santamaría ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Colloidal Stability ◽  
Mesoporous Silica Nanoparticles ◽  
Gene Delivery Vectors

Efficient photoacoustic imaging using indocyanine green (ICG) loaded functionalized mesoporous silica nanoparticles

2019 ◽  
Vol 7 (12) ◽  
pp. 5002-5015 ◽  
Author(s):  
Zanib Chaudhary ◽  
Gul Majid Khan ◽  
Muhammad Mustafa Abeer ◽  
Naisarg Pujara ◽  
Brian Wan-Chi Tse ◽  
...  
Keyword(s):  
Surface Modification ◽  
Mesoporous Silica ◽  
Indocyanine Green ◽  
Silica Nanoparticles ◽  
Photoacoustic Imaging ◽  
Mesoporous Silica Nanoparticles ◽  
Functionalized Mesoporous Silica

Herein, we demonstrate the role of surface modification of nanocarriers on their ability to load and protect sensitive payloads.

scholarly journals Microwave-Synthesized Platinum-Embedded Mesoporous Silica Nanoparticles as Dual-Modality Contrast Agents: Computed Tomography and Optical Imaging

2019 ◽  
Vol 20 (7) ◽  
pp. 1560 ◽  
Author(s):  
Chia-Hui Chu ◽  
Shih-Hsun Cheng ◽  
Nai-Tzu Chen ◽  
Wei-Neng Liao ◽  
Leu-Wei Lo
Keyword(s):  
Computed Tomography ◽  
Mesoporous Silica ◽  
Contrast Agents ◽  
Optical Imaging ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Particle Diameter ◽  
Ct Imaging ◽  
Average Particle ◽  
Dual Modality

Nanoparticle-based imaging contrast agents have drawn tremendous attention especially in multi-modality imaging. In this study, we developed mesoporous silica nanoparticles (MSNs) for use as dual-modality contrast agents for computed tomography (CT) and near-infrared (NIR) optical imaging (OI). A microwave synthesis for preparing naked platinum nanoparticles (nPtNPs) on MSNs (MSNs-Pt) was developed and characterized with physicochemical analysis and imaging systems. The high density of nPtNPs on the surface of the MSNs could greatly enhance the CT contrast. Inductively coupled plasma mass spectrometry (ICP-MS) revealed the MSNs-Pt compositions to be ~14% Pt by weight and TEM revealed an average particle diameter of ~50 nm and covered with ~3 nm diameter nPtNPs. To enhance the OI contrast, the NIR fluorescent dye Dy800 was conjugated to the MSNs-Pt nanochannels. The fluorescence spectra of MSNs-Pt-Dy800 were very similar to unconjugated Dy800. The CT imaging demonstrated that even modest degrees of Pt labeling could result in substantial X-ray attenuation. In vivo imaging of breast tumor-bearing mice treated with PEGylated MSNs-Pt-Dy800 (PEG-MSNs-Pt-Dy800) showed significantly improved contrasts in both fluorescence and CT imaging and the signal intensity within the tumor retained for 24 h post-injection.

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