Acid/redox dual-activated liposomes for tumor-targeted drug delivery and enhanced therapeutic efficacy

RSC Advances ◽  
2015 ◽  
Vol 5 (83) ◽  
pp. 67803-67808 ◽  
Author(s):  
Xuefan Xu ◽  
Lei Zhang ◽  
Assogba G. Assanhou ◽  
Lu Wang ◽  
Yidi Zhang ◽  
...  

Acid/redox dual-activated liposomes support enhanced therapeutic efficacy by overcoming multiple barriers to the intravenous delivery of an anticancer drug.

2020 ◽  
Vol 11 (27) ◽  
pp. 4469-4476 ◽  
Author(s):  
Lu Sun ◽  
Hua Wei ◽  
Xianshuo Zhang ◽  
Chao Meng ◽  
Guiying Kang ◽  
...  

We reported the synthesis of polymeric micelles with a dual-functional sheddable mPEG stealth to realize simultaneously tumor-triggered targeting and intracellular micelle destabilization for enhanced anticancer drug delivery.


RSC Advances ◽  
2015 ◽  
Vol 5 (50) ◽  
pp. 40258-40268 ◽  
Author(s):  
Jing Wang ◽  
Qingqing Tian ◽  
Fang Ding ◽  
Yanyan Yu ◽  
Fanhong Wu

Functionalized graphene oxide (CGO–cRGDyK/POLO) nanosheets were designed and developed for targeted drug delivery to integrin expression.


2015 ◽  
Vol 39 (11) ◽  
pp. 8840-8847 ◽  
Author(s):  
Xifeng Liu ◽  
A. Lee Miller II ◽  
Brian E. Waletzki ◽  
Tewodros K. Mamo ◽  
Michael J. Yaszemski ◽  
...  

An extracellular stable micelle with a folate conjugated surface, a crosslinked core and pH-sensitive hydrolysable bonds was developed for cancer targeted drug delivery.


2019 ◽  
Vol 7 (4) ◽  
pp. 576-585 ◽  
Author(s):  
Yandan Yao ◽  
Phei Er Saw ◽  
Yan Nie ◽  
Ping-Pui Wong ◽  
Linjia Jiang ◽  
...  

A new multifunctional pH-responsive NP platform was developed for targeted anticancer drug delivery and effective breast cancer therapy.


RSC Advances ◽  
2021 ◽  
Vol 11 (31) ◽  
pp. 18809-18817
Author(s):  
Ali Bina ◽  
Heidar Raissi ◽  
Hassan Hashemzadeh ◽  
Farzaneh Farzad

Polymeric nanoparticles have emerged as efficient carriers for anticancer drug delivery because they can improve the solubility of hydrophobic drugs and also can increase the bio-distribution of drugs throughout the bloodstream.


Carbon ◽  
2012 ◽  
Vol 50 (2) ◽  
pp. 622-632 ◽  
Author(s):  
Elena Heister ◽  
Vera Neves ◽  
Constanze Lamprecht ◽  
S.Ravi P. Silva ◽  
Helen M. Coley ◽  
...  

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