Synthesis of polymeric micelles with dual-functional sheddable PEG stealth for enhanced tumor-targeted drug delivery

2020 ◽  
Vol 11 (27) ◽  
pp. 4469-4476 ◽  
Author(s):  
Lu Sun ◽  
Hua Wei ◽  
Xianshuo Zhang ◽  
Chao Meng ◽  
Guiying Kang ◽  
...  

We reported the synthesis of polymeric micelles with a dual-functional sheddable mPEG stealth to realize simultaneously tumor-triggered targeting and intracellular micelle destabilization for enhanced anticancer drug delivery.

RSC Advances ◽  
2015 ◽  
Vol 5 (50) ◽  
pp. 40258-40268 ◽  
Author(s):  
Jing Wang ◽  
Qingqing Tian ◽  
Fang Ding ◽  
Yanyan Yu ◽  
Fanhong Wu

Functionalized graphene oxide (CGO–cRGDyK/POLO) nanosheets were designed and developed for targeted drug delivery to integrin expression.


2015 ◽  
Vol 39 (11) ◽  
pp. 8840-8847 ◽  
Author(s):  
Xifeng Liu ◽  
A. Lee Miller II ◽  
Brian E. Waletzki ◽  
Tewodros K. Mamo ◽  
Michael J. Yaszemski ◽  
...  

An extracellular stable micelle with a folate conjugated surface, a crosslinked core and pH-sensitive hydrolysable bonds was developed for cancer targeted drug delivery.


2019 ◽  
Vol 7 (4) ◽  
pp. 576-585 ◽  
Author(s):  
Yandan Yao ◽  
Phei Er Saw ◽  
Yan Nie ◽  
Ping-Pui Wong ◽  
Linjia Jiang ◽  
...  

A new multifunctional pH-responsive NP platform was developed for targeted anticancer drug delivery and effective breast cancer therapy.


RSC Advances ◽  
2021 ◽  
Vol 11 (31) ◽  
pp. 18809-18817
Author(s):  
Ali Bina ◽  
Heidar Raissi ◽  
Hassan Hashemzadeh ◽  
Farzaneh Farzad

Polymeric nanoparticles have emerged as efficient carriers for anticancer drug delivery because they can improve the solubility of hydrophobic drugs and also can increase the bio-distribution of drugs throughout the bloodstream.


2017 ◽  
Vol 41 (5) ◽  
pp. 2160-2168 ◽  
Author(s):  
Mahdi Rahimi ◽  
Salman Shojaei ◽  
Kazem D. Safa ◽  
Zarrin Ghasemi ◽  
Roya Salehi ◽  
...  

A smart, pH-responsive and biocompatible nanocarrier, aimed to achieve an efficient targeted drug delivery system, was facilely synthesized.


2017 ◽  
Vol 60 ◽  
pp. 244-255 ◽  
Author(s):  
Jiao Guan ◽  
Zun-Qiang Zhou ◽  
Mao-Hua Chen ◽  
Hui-Yan Li ◽  
Da-Nian Tong ◽  
...  

Nanomedicine ◽  
2011 ◽  
Vol 6 (7) ◽  
pp. 1245-1255 ◽  
Author(s):  
Marina Talelli ◽  
Wim E Hennink

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