Microwave assisted novel and regioselective functionalization of imidazopyridines with chromene acetals and β-nitrostyrenes

RSC Advances ◽  
2015 ◽  
Vol 5 (87) ◽  
pp. 70949-70957 ◽  
Author(s):  
L. Chandrasekhara Rao ◽  
N. Satish Kumar ◽  
H. M. Meshram
Keyword(s):  
Catalytic Amount ◽  
Facile Synthesis ◽  
Microwave Assisted ◽  
Regioselective Functionalization

A facile synthesis of novel functionalized imidazopyridines has been accomplished through the condensation of imidazopyridines with chromene hemiacetals or β-nitro styrenes with high regioselectivity and excellent yields in the presence of a catalytic amount of PTSA or InCl3.

Microwave assisted synthesis of novel Pyrazole derivatives and their biological evaluation as anti-bacterial agents

2020 ◽  
Vol 23 ◽  
Author(s):  
Hadis Khodadad ◽  
Farhad Hatamjafari ◽  
Khalil Pourshamsian ◽  
Babak Sadeghi
Keyword(s):  
Antibacterial Activity ◽  
Aromatic Aldehydes ◽  
Catalytic Amount ◽  
Antibacterial Activities ◽  
Structural Features ◽  
Biological Evaluation ◽  
Aureus Strain ◽  
Microwave Assisted Synthesis ◽  
Pyrazole Derivatives ◽  
Microwave Assisted

Aim and Objective: Microwave-assisted condensation of acetophenone 1 and aromatic aldehydes 2 gave chalcone analogs 3, which were cyclized to pyrazole derivatives 6a-f via the reaction with hydrazine hydrate and oxalic acid in the presence of the catalytic amount of acetic acid in ethanol. Materials and Methods: The structural features of the synthesized compounds were characterized by melting point, FT-IR, 1H, 13C NMR and elemental analysis. Results: The antibacterial activities of the synthesized pyrazoles was evaluated against three gram-positive bacteria such as Enterococcus durans, Staphylococcus aureus, Bacillus subtilis and two gram-negative bacteria such as Escherichia coli and Salmonella typhimurium. Conclusion: All the synthesized pyrazoles showed relatively high antibacterial activity against S. aureus strain and none of them demonstrated antibacterial activity against E. coli.

scholarly journals Facile synthesis of bis(indolyl)methanes using iron(III) phosphate

2012 ◽  
Vol 77 (9) ◽  
pp. 1157-1163 ◽  
Author(s):  
Kargar Behbahani ◽  
Masoumeh Sasani
Keyword(s):  
Substitution Reaction ◽  
Electrophilic Substitution ◽  
Catalytic Amount ◽  
Reusable Catalyst ◽  
Electrophilic Substitution Reaction ◽  
Facile Synthesis

A new, convenient and high yielding procedure for the preparation of bis(indolyl)methanes in glycerol by electrophilic substitution reaction of indole with aldehydes in the presence of catalytic amount of FePO4 (5.0 mol%) as a highly stable and reusable catalyst is described.

scholarly journals Microwave-Assisted Facile Synthesis and Crystal Structure of cis-9,10,11,15-Tetrahydro-9,10[3′,4′]-furanoanthracene-12,14-dione.

ChemInform ◽  
2006 ◽  
Vol 37 (34) ◽  
Author(s):  
Weerachai Phutdhawong ◽  
Duang Buddhasukh ◽  
Stephen G. Pyne ◽  
Apinpus Rujiwatra ◽  
Chaveng Pakawatchai
Keyword(s):  
Crystal Structure ◽  
Facile Synthesis ◽  
Synthesis And Crystal Structure ◽  
Microwave Assisted
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