Phenylboronic acid-modified magnetic nanoparticles as a platform for carbon dot conjugation and doxorubicin delivery

2015 ◽  
Vol 3 (27) ◽  
pp. 5532-5543 ◽  
Author(s):  
Mochamad Zakki Fahmi ◽  
Jem-Kun Chen ◽  
Chih-Ching Huang ◽  
Yong-Chien Ling ◽  
Jia-Yaw Chang

This paper reports the development of multifunctional nanoparticles as effective dual-modality molecular imaging probes and drug delivery agents for simultaneous cancer diagnosis and chemotherapy.

RSC Advances ◽  
2016 ◽  
Vol 6 (29) ◽  
pp. 24104-24110 ◽  
Author(s):  
Wei Lu ◽  
Ning Wang ◽  
YanYan Chu ◽  
Linzhu Zhou ◽  
Maolan Li ◽  
...  

CLIC1 antibody-conjugated nano-scale contrast agents exhibit a fast and sensitive detection of gallbladder tumors and may be used in the future as powerful targeted molecular imaging probes for gallbladder cancer diagnosis.


Author(s):  
Rajasekharreddy Pala ◽  
Subhaswaraj Pattnaik ◽  
Yun Zeng ◽  
Siddhardha Busi ◽  
Surya M. Nauli ◽  
...  

2011 ◽  
Vol 10 (6) ◽  
pp. 7290.2011.00003 ◽  
Author(s):  
Fred Reynolds ◽  
Kimberly A. Kelly

Molecular imaging allows clinicians to visualize disease-specific molecules, thereby providing relevant information in the diagnosis and treatment of patients. With advances in genomics and proteomics and underlying mechanisms of disease pathology, the number of targets identified has significantly outpaced the number of developed molecular imaging probes. There has been a concerted effort to bridge this gap with multidisciplinary efforts in chemistry, proteomics, physics, material science, and biology—all essential to progress in molecular imaging probe development. In this review, we discuss target selection, screening techniques, and probe optimization with the aim of developing clinically relevant molecularly targeted imaging agents.


2018 ◽  
Vol 61 (2) ◽  
pp. 68-76 ◽  
Author(s):  
Kusum Vats ◽  
Drishty Satpati ◽  
Rohit Sharma ◽  
Chandan Kumar ◽  
Haladhar Dev Sarma ◽  
...  

2012 ◽  
Vol 40 (10) ◽  
pp. 1607-1615 ◽  
Author(s):  
Jun-Peng ZHENG ◽  
Ming-Ming ZHEN ◽  
Chun-Ru WANG ◽  
Chun-Ying SHU

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