Reduced graphene oxide gated mesoporous silica nanoparticles as a versatile chemo-photothermal therapy system through pH controllable release

2015 ◽  
Vol 3 (30) ◽  
pp. 6377-6384 ◽  
Author(s):  
Ting Ting Wang ◽  
Jing Lan ◽  
Yue Zhang ◽  
Zhu Lian Wu ◽  
Chun Mei Li ◽  
...  

A multifunctional drug delivery system involving coupling photothermal therapy and chemotherapy together was developed, which based on the combination of rGO and MSNs, wherein the cargo molecules could be released in acidic environments due to the cleavage of the CN bond of Schiff bases.

2017 ◽  
Vol 53 (62) ◽  
pp. 8755-8758 ◽  
Author(s):  
Song Wang ◽  
Fei Liu ◽  
Xiang-Ling Li

We constructed a versatile drug delivery system using dual internal stimulus, achieving controllable release and monitoring simultaneously.


Nanoscale ◽  
2015 ◽  
Vol 7 (14) ◽  
pp. 6304-6310 ◽  
Author(s):  
Yuxia Tang ◽  
Hao Hu ◽  
Molly Gu Zhang ◽  
Jibin Song ◽  
Liming Nie ◽  
...  

A photoresponsive drug delivery system was developed for light-mediated drug release and aptamer-targeted cancer therapy.


2017 ◽  
Vol 9 (2) ◽  
pp. 1226-1236 ◽  
Author(s):  
Leihou Shao ◽  
Ruirui Zhang ◽  
Jianqing Lu ◽  
Caiyan Zhao ◽  
Xiongwei Deng ◽  
...  

Mesoporous silica nanoparticles (MSNs) have been attracting great attention for the potential biomedical applications in the last decades. Due to the unique properties, such as tunable mesoporous structure, huge surface area, large pore volume, as well as the functional ability of surface, MSNs exhibit high loading capacity for therapeutic active pharmaceutical ingredients (APIs) and controllable release behavior. In this review, the applications of MSNs in pharmaceutics improving the bioavailability, reducing toxicity of loaded drugs, increasing cellular targeted delivery ability and recent advances in drug delivery are summarized.


2020 ◽  
Vol 3 (5) ◽  
pp. 2577-2587 ◽  
Author(s):  
Xiao Liu ◽  
Xu Wu ◽  
Yuqian Xing ◽  
Ying Zhang ◽  
Xuefei Zhang ◽  
...  

2019 ◽  
Vol 96 ◽  
pp. 138-145 ◽  
Author(s):  
Rong Liu ◽  
Huicong Zhang ◽  
Fangrong Zhang ◽  
Xuandong Wang ◽  
Xiaolong Liu ◽  
...  

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