In situ cross-linked and highly carboxylated poly(vinyl alcohol) nanofibrous membranes for efficient adsorption of proteins

2015 ◽  
Vol 3 (36) ◽  
pp. 7281-7290 ◽  
Author(s):  
Xiaoliang Wang ◽  
Qiuxia Fu ◽  
Xueqin Wang ◽  
Yang Si ◽  
Jianyong Yu ◽  
...  

In situ cross-linked and highly carboxylated poly(vinyl alcohol) nanofibrous membranes for lysozyme adsorption were fabricated by a combination of electrospinning and graft polymerization of poly(vinyl alcohol) and maleic anhydride.

2011 ◽  
Vol 120 (6) ◽  
pp. 3291-3296 ◽  
Author(s):  
Quan Feng ◽  
Xin Xia ◽  
Anfang Wei ◽  
Xueqian Wang ◽  
Qufu Wei ◽  
...  

2019 ◽  
Vol 2019 ◽  
pp. 1-8
Author(s):  
Xiaojuan Zhang ◽  
Wenbin Cai ◽  
Lingyun Hao ◽  
Wei Zhang

This study synthesized poly(vinyl alcohol)/carboxymethyl chitosan/cyanidin (PVA/CMCS/CY) hydrogel films. First, PVA and CMCS were used to synthesize hydrogel films by ultraviolet irradiation. Meanwhile, CY was in situ combined into the hydrogel films through the electrostatic attraction between CMCS and CY. Next, the products were analyzed using Fourier-transform infrared spectroscopy, scanning electron microscopy, contact angle test, swelling analysis, and mechanical property test. The results revealed that compared with PVA/CMCS hydrogel films, the PVA/CMCS/CY hydrogel films had an interporous structure and good swelling and mechanical properties. Moreover, the drug release experiments demonstrated that the PVA/CMCS/CY hydrogel films had a CY encapsulation efficiency of 33.5% with a sustained CY release of up to 60 h. Furthermore, the examined antibacterial activities against Staphylococcus aureus and Escherichia coli showed that the porous PVA/CMCS/CY hydrogel films exhibited a certain inhibition. Cell viability experiments demonstrated that the PVA/CMCS/CY films displayed no obvious cytotoxicity to human umbilical vein endothelial cells.


Sign in / Sign up

Export Citation Format

Share Document