scholarly journals In Situ Preparation and Properties of Poly(vinyl alcohol)/Carboxymethyl Chitosan/Cyanidin Hydrogel Films

2019 ◽  
Vol 2019 ◽  
pp. 1-8
Author(s):  
Xiaojuan Zhang ◽  
Wenbin Cai ◽  
Lingyun Hao ◽  
Wei Zhang

This study synthesized poly(vinyl alcohol)/carboxymethyl chitosan/cyanidin (PVA/CMCS/CY) hydrogel films. First, PVA and CMCS were used to synthesize hydrogel films by ultraviolet irradiation. Meanwhile, CY was in situ combined into the hydrogel films through the electrostatic attraction between CMCS and CY. Next, the products were analyzed using Fourier-transform infrared spectroscopy, scanning electron microscopy, contact angle test, swelling analysis, and mechanical property test. The results revealed that compared with PVA/CMCS hydrogel films, the PVA/CMCS/CY hydrogel films had an interporous structure and good swelling and mechanical properties. Moreover, the drug release experiments demonstrated that the PVA/CMCS/CY hydrogel films had a CY encapsulation efficiency of 33.5% with a sustained CY release of up to 60 h. Furthermore, the examined antibacterial activities against Staphylococcus aureus and Escherichia coli showed that the porous PVA/CMCS/CY hydrogel films exhibited a certain inhibition. Cell viability experiments demonstrated that the PVA/CMCS/CY films displayed no obvious cytotoxicity to human umbilical vein endothelial cells.

1999 ◽  
Vol 1 (11) ◽  
pp. 2749-2753 ◽  
Author(s):  
Masahiro Suzuki ◽  
Takahide Yoshida ◽  
Satoshi Kobayashi ◽  
Toshiki Koyama ◽  
Mutsumi Kimura ◽  
...  

2019 ◽  
Vol 27 (6) ◽  
pp. 523-525
Author(s):  
Vu Khac Hoang Bui ◽  
Duckshin Park ◽  
Minh Kim Nguyen ◽  
Ju-Young Moon ◽  
Young-Chul Lee

2020 ◽  
pp. 152808372091334 ◽  
Author(s):  
Wen-Cheng Chen ◽  
Chia-Ying Ko ◽  
Kai-Chi Chang ◽  
Chih-Hua Chen ◽  
Dan-Jae Lin

Silver ions (Ag+) and silver nanoparticles (AgNPs) are effective antimicrobial agents that act against a broad spectrum of bacteria. The releasing quantitation of free Ag+ is exclusively responsible for the biological toxicity, while limiting the free Ag+ in AgNPs or in polymers would largely ease the conditions. In this study, the different concentrations of silver nitrate (AgNO3) in poly(vinyl alcohol) (PVA) and an optional preheat treatment on the spinning solution before electrospinning to form the Ag+/AgNPs/PVA fibrous membranes through electrospinning technology were investigated. The morphologies, AgNPs dispersity within the PVA matrix, and the sterilizations (UV irradiation and autoclave) for Ag+/AgNPs/PVA fibrous membranes were characterized. The antibacterial activities of Ag/PVA composite membranes combined with the in-house prepared light-cured resin were also investigated. Results showed that the AgNPs/PVA fibrous membranes with antibacterial capability can be produced with the addition of at least 5 wt.% of AgNO3 to PVA. The antibacterial activities of Ag content in the PVA matrix were increased in the high presence of Ag. Noteworthy, the antibacterial enhancing effect was observed for the spinning solution groups after preheating treatment at 100°C for 1 h. The result suggests that Ag/PVA fibrous membranes sterilized by autoclave hindered antibacterial effectiveness due to the significant particle size changes in the generation of large-sized AgNPs. Nevertheless, the direct application of UV light irradiation to Ag/PVA fibrous membranes preserves their active antibacterial profile against Staphylococcus aureus and Escherichia coli. We also demonstrated that these designed AgNPs/PVA composite membranes can equip the resin with an active antibacterial capability, could benefit from the prevented bacteria breeding in microleakages and thus further reduce the possibility for secondary caries.


2020 ◽  
Vol 3 (3) ◽  
pp. 1681-1689 ◽  
Author(s):  
John H. Thurston ◽  
Andrew J. Clifford ◽  
Bradley S. Henderson ◽  
Tyler R. Smith ◽  
Dylan Quintana ◽  
...  

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