Rapid in situ endothelialization of a small diameter vascular graft with catalytic nitric oxide generation and promoted endothelial cell adhesion

2015 ◽  
Vol 3 (47) ◽  
pp. 9212-9222 ◽  
Author(s):  
Yuanyuan Wang ◽  
Siyuan Chen ◽  
Yiwa Pan ◽  
Jingchen Gao ◽  
Di Tang ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Cell Adhesion ◽  
Endothelial Cell ◽  
Vascular Graft ◽  
Small Diameter ◽  
Endothelial Cell Adhesion

Rapidin situendothelialization of a small diameter vascular graft with catalytic nitric oxide generation and promoted endothelial cell adhesion.

Nano-scale clustering of integrin-binding ligands regulates endothelial cell adhesion, migration, and endothelialization rate: novel materials for small diameter vascular graft applications

2017 ◽  
Vol 5 (30) ◽  
pp. 5942-5953 ◽  
Author(s):  
Fatemeh Karimi ◽  
Thomas G. McKenzie ◽  
Andrea J. O'Connor ◽  
Greg G. Qiao ◽  
Daniel E. Heath
Keyword(s):  
Cell Adhesion ◽  
Endothelial Cell ◽  
Vascular Graft ◽  
Small Diameter ◽  
Novel Materials ◽  
Nano Scale ◽  
Endothelial Cell Adhesion

Blood contacting devices are commonly used in today's medical landscape.

Modulation of oxidized low-density lipoprotein-induced microvascular dysfunction by nitric oxide

1995 ◽  
Vol 268 (4) ◽  
pp. H1643-H1650 ◽  
Author(s):  
L. Liao ◽  
D. N. Granger
Keyword(s):  
Nitric Oxide ◽  
Mast Cell ◽  
Cell Adhesion ◽  
Endothelial Cell ◽  
Microvascular Dysfunction ◽  
Mast Cell Degranulation ◽  
Low Density ◽  
No Donors ◽  
Albumin Leakage ◽  
Endothelial Cell Adhesion

The objectives of this study were to determine 1) whether the leukocyte-endothelial cell adhesion in postcapillary venules elicited by copper-oxidized low-density lipoproteins (Cu-LDL) is accompanied by enhanced vascular albumin leakage and mast cell degranulation and 2) whether nitric oxide (NO) donors attenuate the Cu-LDL-induced microvascular dysfunction. Infusion of Cu-LDL, but not normal LDL, caused significant increases in leukocyte rolling, adherence, emigration, mast cell degranulation, and an enhanced albumin leakage in rat mesenteric venules. Treatment with the NO donors sodium nitroprusside and spermine-NO or pretreatment with superoxide dismutase or L-arginine significantly reduced the Cu-LDL-induced leukocyte adherence, emigration, mast cell degranulation, and albumin leakage, whereas spermine and D-arginine had no effect. These results indicate that NO protects the microvasculature against the deleterious effects of oxidized LDL, an effect that may be related to NO's ability to reduce leukocyte-endothelial cell adhesion and/or prevent mast cell degranulation.

Laser-based in situ embedding of metal nanoparticles into bioextruded alginate hydrogel tubes enhances human endothelial cell adhesion

Nano Research ◽  
2016 ◽  
Vol 9 (11) ◽  
pp. 3407-3427 ◽  
Author(s):  
Andreas Blaeser ◽  
Nina Million ◽  
Daniela Filipa Duarte Campos ◽  
Lisa Gamrad ◽  
Marius Köpf ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Endothelial Cell ◽  
Metal Nanoparticles ◽  
Human Endothelial Cell ◽  
Alginate Hydrogel ◽  
In Situ Embedding ◽  
Endothelial Cell Adhesion
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