scholarly journals Metal-catalyzed oxidation of Aβ and the resulting reorganization of Cu binding sites promote ROS production

Metallomics ◽  
2016 ◽  
Vol 8 (10) ◽  
pp. 1081-1089 ◽  
Author(s):  
Clémence Cheignon ◽  
Peter Faller ◽  
Denis Testemale ◽  
Christelle Hureau ◽  
Fabrice Collin
Keyword(s):  
Binding Sites ◽  
The Self ◽  
Ros Production ◽  
Copper Coordination ◽  
Metal Catalyzed Oxidation ◽  
Metal Catalyzed ◽  
Catalyzed Oxidation

Aβ oxidation due to HO˙ production by Cu–Aβ/ascorbate changes copper coordination and leads to the self-enhancement of HO˙ production and release.

scholarly journals Metal-catalyzed oxidation of human serum albumin does not alter the interactive binding to the two principal drug binding sites

2018 ◽  
Vol 14 ◽  
pp. 155-160 ◽  
Author(s):  
Keishi Yamasaki ◽  
Koji Nishi ◽  
Makoto Anraku ◽  
Kazuaki Taguchi ◽  
Toru Maruyama ◽  
...  
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Binding Sites ◽  
Drug Binding ◽  
Drug Binding Sites ◽  
Metal Catalyzed Oxidation ◽  
Metal Catalyzed ◽  
Catalyzed Oxidation

Ambivalent role of ascorbic acid in the metal-catalyzed oxidation of oligopeptides

2021 ◽  
pp. 111510
Author(s):  
Nikolett Bodnár ◽  
Katalin Várnagy ◽  
Lajos Nagy ◽  
Gizella Csire ◽  
Csilla Kállay
Keyword(s):  
Ascorbic Acid ◽  
Metal Catalyzed Oxidation ◽  
Metal Catalyzed ◽  
Catalyzed Oxidation

scholarly journals Metal-catalyzed oxidation renders silver intensification selective. Applications for the histochemistry of diaminobenzidine and neurofibrillary changes.

1986 ◽  
Vol 34 (12) ◽  
pp. 1667-1672 ◽  
Author(s):  
F Gallyas ◽  
J R Wolff
Keyword(s):  
Hydrogen Peroxide ◽  
Oxidative Polymerization ◽  
Silver Coating ◽  
Neurofibrillary Changes ◽  
Iodide Ions ◽  
Tissue Sections ◽  
Metal Catalyzed Oxidation ◽  
Pre Treatment ◽  
Metal Catalyzed ◽  
Catalyzed Oxidation

Physical developers can increase the visibility of end products of certain histochemical reactions, such as oxidative polymerization of diaminobenzidine and selective binding of complex silver iodide ions to Alzheimer's neurofibrillary changes. Unfortunately, this intensification by silver coating is generally superimposed on a nonspecific staining originating from the argyrophil III reaction, which also takes place when tissue sections are treated with physical developers. The present study reveals that the argyrophil III reaction can be suppressed when tissue sections are treated with certain metal ions and hydrogen peroxide before they are transferred to the physical developer. The selective intensification of Alzheimer's neurofibrillary changes requires a pre-treatment with lanthanum nitrate (10 mM/liter) and 3% hydrogen peroxide for 1 hr. The diaminobenzidine reaction can be selectively intensified when physical development is preceded by consecutive treatments with copper sulfate (10 mM/liter, pH 5, 10 min) and hydrogen peroxide (3%, pH 7, 10 min). In peroxidase histochemistry, this high-grade intensification may help to increase specificity and reduce the threshold of detectability in tracing neurons with horseradish peroxidase or in immunohistochemistry when the peroxidase-antiperoxidase method is used.

scholarly journals Identification of the Copper(II) Coordinating Residues in the Prion Protein by Metal-Catalyzed Oxidation Mass Spectrometry: Evidence for Multiple Isomers at Low Copper(II) Loadings†

Biochemistry ◽  
2008 ◽  
Vol 47 (35) ◽  
pp. 9258-9268 ◽  
Author(s):  
Rapole Srikanth ◽  
Jonathan Wilson ◽  
Colin S. Burns ◽  
Richard W. Vachet
Keyword(s):  
Mass Spectrometry ◽  
Prion Protein ◽  
Metal Catalyzed Oxidation ◽  
Metal Catalyzed ◽  
Catalyzed Oxidation

ChemInform Abstract: Metal-Catalyzed Oxidation of C-X (X: S, O) in Ionic Liquids

ChemInform ◽  
2016 ◽  
Vol 47 (39) ◽  
Author(s):  
Andreia A. Rosatella ◽  
Carlos A. M. Afonso
Keyword(s):  
Ionic Liquids ◽  
Metal Catalyzed Oxidation ◽  
Metal Catalyzed ◽  
Catalyzed Oxidation
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