A dual-site two-photon fluorescent probe for visualizing mitochondrial aminothiols in living cells and mouse liver tissues

2016 ◽  
Vol 40 (9) ◽  
pp. 7399-7406 ◽  
Author(s):  
Fangfang Meng ◽  
Yong Liu ◽  
Xiaoqiang Yu ◽  
Weiying Lin

In this work, we developed a dual-site two-photon (TP) fluorescent RSH probe (CA-TPP) for imaging mitochondrial RSH in living systems. In particular, probe CA-TPP was capable of using TP fluorescence to track mitochondrial RSH over a long period for the first time.

2016 ◽  
Vol 52 (43) ◽  
pp. 7016-7019 ◽  
Author(s):  
Yong Liu ◽  
Fangfang Meng ◽  
Longwei He ◽  
Keyin Liu ◽  
Weiying Lin

We have firstly developed a fluorescent probe TP-PMVC, which can monitor lysosomes and lysosomal H2S with dual signal.


2016 ◽  
Vol 52 (57) ◽  
pp. 8838-8841 ◽  
Author(s):  
Yong Liu ◽  
Fangfang Meng ◽  
Longwei He ◽  
Xiaoqiang Yu ◽  
Weiying Lin

In this work, we developed a unique fluorescent probe HVC-6 for highly sensitive detection of RNA in pure water systems and living systems by aggregation–disaggregation of the probe for the first time.


Luminescence ◽  
2018 ◽  
Vol 33 (7) ◽  
pp. 1275-1280 ◽  
Author(s):  
Chao Wang ◽  
Baoli Dong ◽  
Xiuqi Kong ◽  
Nan Zhang ◽  
Wenhui Song ◽  
...  

2019 ◽  
Vol 11 (12) ◽  
pp. 1580-1584 ◽  
Author(s):  
Li Wang ◽  
Mingguang Ren ◽  
Zihong Li ◽  
Lixuan Dai ◽  
Weiying Lin

We developed a new ratiometric two-photon fluorescent probe (CR-HA). Fluorescence imaging showed that CR-HA was suitable for the visualization of HOCl changes in living cells/tissues.


2016 ◽  
Vol 52 (67) ◽  
pp. 10289-10292 ◽  
Author(s):  
Xiaoguang Yang ◽  
Yibo Zhou ◽  
Xiufang Zhang ◽  
Sheng Yang ◽  
Yun Chen ◽  
...  

A TP-FRET-based ratiometric two-photon fluorescent probe for endogenous SO2 derivative imaging in mitochondria has been developed for the first time.


2021 ◽  
Author(s):  
Qiaomei Yang ◽  
Liyi Zhou ◽  
Longpeng Peng ◽  
Gangqiang Yuan ◽  
Haiyuan Ding ◽  
...  

Hydrogen sulfide (H2S) is one of the important gaseous signal molecules and plays key roles in various biologically crucial processes. In this work, we report a novel two-photon near-infrared (TP-NIR)...


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